Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 98

1.

Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity.

Daly J, Bebenek K, Watt DL, Richter K, Jiang C, Zhao ML, Ray M, McGregor WG, Kunkel TA, Diaz M.

J Immunol. 2012 Jun 1;188(11):5528-37. doi: 10.4049/jimmunol.1102629. Epub 2012 Apr 30.

2.

A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta.

Faili A, Stary A, Delbos F, Weller S, Aoufouchi S, Sarasin A, Weill JC, Reynaud CA.

J Immunol. 2009 May 15;182(10):6353-9. doi: 10.4049/jimmunol.0900177.

3.

DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.

Masuda K, Ouchida R, Takeuchi A, Saito T, Koseki H, Kawamura K, Tagawa M, Tokuhisa T, Azuma T, O-Wang J.

Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13986-91. Epub 2005 Sep 19.

4.

DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.

Schrader CE, Linehan EK, Ucher AJ, Bertocci B, Stavnezer J.

DNA Repair (Amst). 2013 Dec;12(12):1087-93. doi: 10.1016/j.dnarep.2013.09.002. Epub 2013 Sep 29.

5.

Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse.

Delbos F, De Smet A, Faili A, Aoufouchi S, Weill JC, Reynaud CA.

J Exp Med. 2005 Apr 18;201(8):1191-6. Epub 2005 Apr 11.

6.
7.

Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability.

Schenten D, Kracker S, Esposito G, Franco S, Klein U, Murphy M, Alt FW, Rajewsky K.

J Exp Med. 2009 Feb 16;206(2):477-90. doi: 10.1084/jem.20080669. Epub 2009 Feb 9.

8.

DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes.

Maul RW, MacCarthy T, Frank EG, Donigan KA, McLenigan MP, Yang W, Saribasak H, Huston DE, Lange SS, Woodgate R, Gearhart PJ.

J Exp Med. 2016 Aug 22;213(9):1675-83. doi: 10.1084/jem.20151227. Epub 2016 Jul 25.

9.

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

Zan H, Komori A, Li Z, Cerutti A, Schaffer A, Flajnik MF, Diaz M, Casali P.

Immunity. 2001 May;14(5):643-53.

10.

Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.

Martomo SA, Saribasak H, Yokoi M, Hanaoka F, Gearhart PJ.

DNA Repair (Amst). 2008 Sep 1;7(9):1603-8. doi: 10.1016/j.dnarep.2008.04.002. Epub 2008 May 16.

11.
13.

DNA polymerase kappa deficiency does not affect somatic hypermutation in mice.

Schenten D, Gerlach VL, Guo C, Velasco-Miguel S, Hladik CL, White CL, Friedberg EC, Rajewsky K, Esposito G.

Eur J Immunol. 2002 Nov;32(11):3152-60.

14.

Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions.

Li S, Zhao Y, Wang JY.

Mol Immunol. 2013 Mar;53(3):214-7. doi: 10.1016/j.molimm.2012.08.009. Epub 2012 Sep 4.

PMID:
22960197
15.

Cutting edge: DNA polymerases mu and lambda are dispensable for Ig gene hypermutation.

Bertocci B, De Smet A, Flatter E, Dahan A, Bories JC, Landreau C, Weill JC, Reynaud CA.

J Immunol. 2002 Apr 15;168(8):3702-6.

16.

Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes.

Masuda K, Ouchida R, Hikida M, Nakayama M, Ohara O, Kurosaki T, O-Wang J.

DNA Repair (Amst). 2006 Nov 8;5(11):1384-91. Epub 2006 Aug 4.

PMID:
16890500
17.

DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions.

Saribasak H, Maul RW, Cao Z, Yang WW, Schenten D, Kracker S, Gearhart PJ.

J Exp Med. 2012 Jun 4;209(6):1075-81. doi: 10.1084/jem.20112234. Epub 2012 May 21.

18.

Mutation frequency vs. mutation patterns: a comparison of the results in spleen and Peyer's patches.

Wang JY.

DNA Repair (Amst). 2008 Sep 1;7(9):1408-10; author reply 1411-2. doi: 10.1016/j.dnarep.2008.06.003. Epub 2008 Jul 10. No abstract available.

PMID:
18585483
20.

Normal immunoglobulin gene somatic hypermutation in Pol kappa-Pol iota double-deficient mice.

Shimizu T, Azuma T, Ishiguro M, Kanjo N, Yamada S, Ohmori H.

Immunol Lett. 2005 May 15;98(2):259-64. Epub 2004 Dec 15.

PMID:
15860226

Supplemental Content

Support Center