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Items: 1 to 20 of 169

1.

MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes.

Jayawardena TM, Egemnazarov B, Finch EA, Zhang L, Payne JA, Pandya K, Zhang Z, Rosenberg P, Mirotsou M, Dzau VJ.

Circ Res. 2012 May 25;110(11):1465-73. doi: 10.1161/CIRCRESAHA.112.269035. Epub 2012 Apr 26.

2.

MicroRNA induced cardiac reprogramming in vivo: evidence for mature cardiac myocytes and improved cardiac function.

Jayawardena TM, Finch EA, Zhang L, Zhang H, Hodgkinson CP, Pratt RE, Rosenberg PB, Mirotsou M, Dzau VJ.

Circ Res. 2015 Jan 30;116(3):418-24. doi: 10.1161/CIRCRESAHA.116.304510. Epub 2014 Oct 28.

3.

MicroRNAs and Cardiac Regeneration.

Hodgkinson CP, Kang MH, Dal-Pra S, Mirotsou M, Dzau VJ.

Circ Res. 2015 May 8;116(10):1700-11. doi: 10.1161/CIRCRESAHA.116.304377. Review.

4.

Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails.

Fu Y, Huang C, Xu X, Gu H, Ye Y, Jiang C, Qiu Z, Xie X.

Cell Res. 2015 Sep;25(9):1013-24. doi: 10.1038/cr.2015.99. Epub 2015 Aug 21.

5.

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes.

Qian L, Huang Y, Spencer CI, Foley A, Vedantham V, Liu L, Conway SJ, Fu JD, Srivastava D.

Nature. 2012 May 31;485(7400):593-8. doi: 10.1038/nature11044.

6.

Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells.

Lee K, Yu P, Lingampalli N, Kim HJ, Tang R, Murthy N.

Int J Nanomedicine. 2015 Mar 6;10:1841-54. doi: 10.2147/IJN.S75124. eCollection 2015.

7.

Direct reprogramming of cardiac fibroblasts to cardiomyocytes using microRNAs.

Jayawardena T, Mirotsou M, Dzau VJ.

Methods Mol Biol. 2014;1150:263-72. doi: 10.1007/978-1-4939-0512-6_18.

PMID:
24744005
8.

Single-Dose Intracardiac Injection of Pro-Regenerative MicroRNAs Improves Cardiac Function After Myocardial Infarction.

Lesizza P, Prosdocimo G, Martinelli V, Sinagra G, Zacchigna S, Giacca M.

Circ Res. 2017 Apr 14;120(8):1298-1304. doi: 10.1161/CIRCRESAHA.116.309589. Epub 2017 Jan 11.

PMID:
28077443
9.

Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5.

Chen JX, Krane M, Deutsch MA, Wang L, Rav-Acha M, Gregoire S, Engels MC, Rajarajan K, Karra R, Abel ED, Wu JC, Milan D, Wu SM.

Circ Res. 2012 Jun 22;111(1):50-5. doi: 10.1161/CIRCRESAHA.112.270264. Epub 2012 May 10.

10.

Direct cardiac reprogramming: progress and challenges in basic biology and clinical applications.

Sadahiro T, Yamanaka S, Ieda M.

Circ Res. 2015 Apr 10;116(8):1378-91. doi: 10.1161/CIRCRESAHA.116.305374. Review.

11.

MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures.

Muraoka N, Yamakawa H, Miyamoto K, Sadahiro T, Umei T, Isomi M, Nakashima H, Akiyama M, Wada R, Inagawa K, Nishiyama T, Kaneda R, Fukuda T, Takeda S, Tohyama S, Hashimoto H, Kawamura Y, Goshima N, Aeba R, Yamagishi H, Fukuda K, Ieda M.

EMBO J. 2014 Jul 17;33(14):1565-81. doi: 10.15252/embj.201387605. Epub 2014 Jun 11.

12.

Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes.

Zhou H, Dickson ME, Kim MS, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11864-9. doi: 10.1073/pnas.1516237112. Epub 2015 Sep 9.

13.

Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success.

Addis RC, Ifkovits JL, Pinto F, Kellam LD, Esteso P, Rentschler S, Christoforou N, Epstein JA, Gearhart JD.

J Mol Cell Cardiol. 2013 Jul;60:97-106. doi: 10.1016/j.yjmcc.2013.04.004. Epub 2013 Apr 13.

14.

Direct cardiomyocyte reprogramming: a new direction for cardiovascular regenerative medicine.

Yi BA, Mummery CL, Chien KR.

Cold Spring Harb Perspect Med. 2013 Sep 1;3(9):a014050. doi: 10.1101/cshperspect.a014050. Review.

15.

Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming.

Mohamed TM, Stone NR, Berry EC, Radzinsky E, Huang Y, Pratt K, Ang YS, Yu P, Wang H, Tang S, Magnitsky S, Ding S, Ivey KN, Srivastava D.

Circulation. 2017 Mar 7;135(10):978-995. doi: 10.1161/CIRCULATIONAHA.116.024692. Epub 2016 Nov 10.

PMID:
27834668
16.

Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.

Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D.

Cell. 2010 Aug 6;142(3):375-86. doi: 10.1016/j.cell.2010.07.002.

17.

Heart repair by reprogramming non-myocytes with cardiac transcription factors.

Song K, Nam YJ, Luo X, Qi X, Tan W, Huang GN, Acharya A, Smith CL, Tallquist MD, Neilson EG, Hill JA, Bassel-Duby R, Olson EN.

Nature. 2012 May 13;485(7400):599-604. doi: 10.1038/nature11139.

18.

Direct reprogramming of fibroblasts into cardiomyocytes for cardiac regenerative medicine.

Fu JD, Srivastava D.

Circ J. 2015;79(2):245-54. doi: 10.1253/circj.CJ-14-1372. Epub 2015 Jan 16. Review.

19.

Direct reprogramming of mouse fibroblasts into cardiac myocytes.

Inagawa K, Ieda M.

J Cardiovasc Transl Res. 2013 Feb;6(1):37-45. doi: 10.1007/s12265-012-9412-5. Epub 2012 Oct 3. Review.

PMID:
23054660
20.

Induction of human cardiomyocyte-like cells from fibroblasts by defined factors.

Wada R, Muraoka N, Inagawa K, Yamakawa H, Miyamoto K, Sadahiro T, Umei T, Kaneda R, Suzuki T, Kamiya K, Tohyama S, Yuasa S, Kokaji K, Aeba R, Yozu R, Yamagishi H, Kitamura T, Fukuda K, Ieda M.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12667-72. doi: 10.1073/pnas.1304053110. Epub 2013 Jul 16.

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