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Items: 1 to 20 of 84

1.

Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.

Shay KP, Michels AJ, Li W, Kong AN, Hagen TM.

Biochim Biophys Acta. 2012 Jun;1823(6):1102-9. doi: 10.1016/j.bbamcr.2012.04.002. Epub 2012 Apr 13.

2.

La autoantigen mediates oxidant induced de novo Nrf2 protein translation.

Zhang J, Dinh TN, Kappeler K, Tsaprailis G, Chen QM.

Mol Cell Proteomics. 2012 Jun;11(6):M111.015032. doi: 10.1074/mcp.M111.015032. Epub 2011 Dec 29.

3.

α-Lipoic acid protects against the cytotoxicity and oxidative stress induced by cadmium in HepG2 cells through regeneration of glutathione by glutathione reductase via Nrf2/ARE signaling pathway.

Shi C, Zhou X, Zhang J, Wang J, Xie H, Wu Z.

Environ Toxicol Pharmacol. 2016 Jul;45:274-81. doi: 10.1016/j.etap.2016.06.003. Epub 2016 Jun 5.

PMID:
27343752
4.

Translational control of nrf2 protein in activation of antioxidant response by oxidants.

Purdom-Dickinson SE, Sheveleva EV, Sun H, Chen QM.

Mol Pharmacol. 2007 Oct;72(4):1074-81. Epub 2007 Jul 25.

5.

Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes.

Valdecantos MP, Prieto-Hontoria PL, Pardo V, Módol T, Santamaría B, Weber M, Herrero L, Serra D, Muntané J, Cuadrado A, Moreno-Aliaga MJ, Alfredo Martínez J, Valverde ÁM.

Free Radic Biol Med. 2015 Jul;84:263-78. doi: 10.1016/j.freeradbiomed.2015.03.019. Epub 2015 Apr 1.

PMID:
25841776
6.

Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression.

Kaspar JW, Jaiswal AK.

FASEB J. 2011 Mar;25(3):1076-87. doi: 10.1096/fj.10-171553. Epub 2010 Nov 19.

7.

A combination of lipoic acid plus coenzyme Q10 induces PGC1α, a master switch of energy metabolism, improves stress response, and increases cellular glutathione levels in cultured C2C12 skeletal muscle cells.

Wagner AE, Ernst IM, Birringer M, Sancak O, Barella L, Rimbach G.

Oxid Med Cell Longev. 2012;2012:835970. doi: 10.1155/2012/835970. Epub 2012 May 9.

8.

An internal ribosomal entry site mediates redox-sensitive translation of Nrf2.

Li W, Thakor N, Xu EY, Huang Y, Chen C, Yu R, Holcik M, Kong AN.

Nucleic Acids Res. 2010 Jan;38(3):778-88. doi: 10.1093/nar/gkp1048. Epub 2009 Nov 24.

9.

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.

Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu RM, Hagen TM.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3381-6. Epub 2004 Feb 25.

10.

Proteasome inhibition induces both antioxidant and hb f responses in sickle cell disease via the nrf2 pathway.

Pullarkat V, Meng Z, Tahara SM, Johnson CS, Kalra VK.

Hemoglobin. 2014;38(3):188-95. doi: 10.3109/03630269.2014.898651. Epub 2014 Mar 26.

PMID:
24670032
11.

Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells.

Steele ML, Fuller S, Patel M, Kersaitis C, Ooi L, Münch G.

Redox Biol. 2013 Sep 12;1:441-5. doi: 10.1016/j.redox.2013.08.006. eCollection 2013.

13.

Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline.

Koriyama Y, Nakayama Y, Matsugo S, Kato S.

Brain Res. 2013 Mar 7;1499:145-57. doi: 10.1016/j.brainres.2012.12.041. Epub 2013 Jan 4.

PMID:
23295186
15.
16.

Bilirubin mediated oxidative stress involves antioxidant response activation via Nrf2 pathway.

Qaisiya M, Coda Zabetta CD, Bellarosa C, Tiribelli C.

Cell Signal. 2014 Mar;26(3):512-20. doi: 10.1016/j.cellsig.2013.11.029. Epub 2013 Dec 2.

PMID:
24308969
17.
18.

High basal nuclear levels of Nrf2 in acute myeloid leukemia reduces sensitivity to proteasome inhibitors.

Rushworth SA, Bowles KM, MacEwan DJ.

Cancer Res. 2011 Mar 1;71(5):1999-2009. doi: 10.1158/0008-5472.CAN-10-3018. Epub 2011 Jan 6.

19.
20.

Sulforaphane and alpha-lipoic acid upregulate the expression of the pi class of glutathione S-transferase through c-jun and Nrf2 activation.

Lii CK, Liu KL, Cheng YP, Lin AH, Chen HW, Tsai CW.

J Nutr. 2010 May;140(5):885-92. doi: 10.3945/jn.110.121418. Epub 2010 Mar 17.

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