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Items: 1 to 20 of 140

1.

Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management.

Kavlock R, Chandler K, Houck K, Hunter S, Judson R, Kleinstreuer N, Knudsen T, Martin M, Padilla S, Reif D, Richard A, Rotroff D, Sipes N, Dix D.

Chem Res Toxicol. 2012 Jul 16;25(7):1287-302. doi: 10.1021/tx3000939. Epub 2012 May 15.

PMID:
22519603
2.

Computational toxicology as implemented by the U.S. EPA: providing high throughput decision support tools for screening and assessing chemical exposure, hazard and risk.

Kavlock R, Dix D.

J Toxicol Environ Health B Crit Rev. 2010 Feb;13(2-4):197-217. doi: 10.1080/10937404.2010.483935.

PMID:
20574897
3.

The ToxCast program for prioritizing toxicity testing of environmental chemicals.

Dix DJ, Houck KA, Martin MT, Richard AM, Setzer RW, Kavlock RJ.

Toxicol Sci. 2007 Jan;95(1):5-12. Epub 2006 Sep 8.

PMID:
16963515
4.

Advancing exposure characterization for chemical evaluation and risk assessment.

Cohen Hubal EA, Richard A, Aylward L, Edwards S, Gallagher J, Goldsmith MR, Isukapalli S, Tornero-Velez R, Weber E, Kavlock R.

J Toxicol Environ Health B Crit Rev. 2010 Feb;13(2-4):299-313. doi: 10.1080/10937404.2010.483947.

PMID:
20574904
5.

Analysis of Pfizer compounds in EPA's ToxCast chemicals-assay space.

Shah F, Greene N.

Chem Res Toxicol. 2014 Jan 21;27(1):86-98. doi: 10.1021/tx400343t. Epub 2013 Dec 11.

PMID:
24328225
6.

Integrating mechanistic and polymorphism data to characterize human genetic susceptibility for environmental chemical risk assessment in the 21st century.

Mortensen HM, Euling SY.

Toxicol Appl Pharmacol. 2013 Sep 15;271(3):395-404. doi: 10.1016/j.taap.2011.01.015. Epub 2011 Feb 1.

PMID:
21291902
7.

Profiling bioactivity of the ToxCast chemical library using BioMAP primary human cell systems.

Houck KA, Dix DJ, Judson RS, Kavlock RJ, Yang J, Berg EL.

J Biomol Screen. 2009 Oct;14(9):1054-66. doi: 10.1177/1087057109345525. Epub 2009 Sep 22.

PMID:
19773588
8.

Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB.

Knudsen TB, Martin MT, Kavlock RJ, Judson RS, Dix DJ, Singh AV.

Reprod Toxicol. 2009 Sep;28(2):209-19. doi: 10.1016/j.reprotox.2009.03.016. Epub 2009 Apr 10.

PMID:
19446433
9.

Predictive model of rat reproductive toxicity from ToxCast high throughput screening.

Martin MT, Knudsen TB, Reif DM, Houck KA, Judson RS, Kavlock RJ, Dix DJ.

Biol Reprod. 2011 Aug;85(2):327-39. doi: 10.1095/biolreprod.111.090977. Epub 2011 May 12.

PMID:
21565999
10.

Activity profiles of 309 ToxCastâ„¢ chemicals evaluated across 292 biochemical targets.

Knudsen TB, Houck KA, Sipes NS, Singh AV, Judson RS, Martin MT, Weissman A, Kleinstreuer NC, Mortensen HM, Reif DM, Rabinowitz JR, Setzer RW, Richard AM, Dix DJ, Kavlock RJ.

Toxicology. 2011 Mar 28;282(1-2):1-15. doi: 10.1016/j.tox.2010.12.010. Epub 2011 Jan 18.

PMID:
21251949
11.

Behavioral toxicology in the 21st century: challenges and opportunities for behavioral scientists. Summary of a symposium presented at the annual meeting of the neurobehavioral teratology society, June, 2009.

Bushnell PJ, Kavlock RJ, Crofton KM, Weiss B, Rice DC.

Neurotoxicol Teratol. 2010 May-Jun;32(3):313-28. doi: 10.1016/j.ntt.2010.02.002. Epub 2010 Feb 17.

PMID:
20171276
12.

ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology.

Richard AM, Judson RS, Houck KA, Grulke CM, Volarath P, Thillainadarajah I, Yang C, Rathman J, Martin MT, Wambaugh JF, Knudsen TB, Kancherla J, Mansouri K, Patlewicz G, Williams AJ, Little SB, Crofton KM, Thomas RS.

Chem Res Toxicol. 2016 Aug 15;29(8):1225-51. doi: 10.1021/acs.chemrestox.6b00135. Epub 2016 Jul 20.

13.

Exposure science and the U.S. EPA National Center for Computational Toxicology.

Cohen Hubal EA, Richard AM, Shah I, Gallagher J, Kavlock R, Blancato J, Edwards SW.

J Expo Sci Environ Epidemiol. 2010 May;20(3):231-6. doi: 10.1038/jes.2008.70. Epub 2008 Nov 5. Review.

PMID:
18985077
14.

Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database.

Martin MT, Judson RS, Reif DM, Kavlock RJ, Dix DJ.

Environ Health Perspect. 2009 Mar;117(3):392-9. doi: 10.1289/ehp.0800074. Epub 2008 Oct 20.

15.

Environmental impact on vascular development predicted by high-throughput screening.

Kleinstreuer NC, Judson RS, Reif DM, Sipes NS, Singh AV, Chandler KJ, Dewoskin R, Dix DJ, Kavlock RJ, Knudsen TB.

Environ Health Perspect. 2011 Nov;119(11):1596-603. doi: 10.1289/ehp.1103412. Epub 2011 Jul 25.

16.

Hierarchical dose-response modeling for high-throughput toxicity screening of environmental chemicals.

Wilson A, Reif DM, Reich BJ.

Biometrics. 2014 Mar;70(1):237-46. doi: 10.1111/biom.12114. Epub 2014 Jan 7.

PMID:
24397816
17.

ACToR--Aggregated Computational Toxicology Resource.

Judson R, Richard A, Dix D, Houck K, Elloumi F, Martin M, Cathey T, Transue TR, Spencer R, Wolf M.

Toxicol Appl Pharmacol. 2008 Nov 15;233(1):7-13. doi: 10.1016/j.taap.2007.12.037. Epub 2008 Jul 11.

PMID:
18671997
18.

Economic benefits of using adaptive predictive models of reproductive toxicity in the context of a tiered testing program.

Martin MT, Knudsen TB, Judson RS, Kavlock RJ, Dix DJ.

Syst Biol Reprod Med. 2012 Feb;58(1):3-9. doi: 10.3109/19396368.2011.652288.

PMID:
22239076
19.

In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.

Judson R, Houck K, Martin M, Knudsen T, Thomas RS, Sipes N, Shah I, Wambaugh J, Crofton K.

Basic Clin Pharmacol Toxicol. 2014 Jul;115(1):69-76. doi: 10.1111/bcpt.12239. Epub 2014 Apr 22. Review.

20.

Chemical Safety for Sustainability (CSS): human in vivo biomonitoring data for complementing results from in vitro toxicology--a commentary.

Pleil JD, Williams MA, Sobus JR.

Toxicol Lett. 2012 Dec 17;215(3):201-7. doi: 10.1016/j.toxlet.2012.10.011. Epub 2012 Oct 30. Review.

PMID:
23116968

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