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Items: 1 to 20 of 113

1.

Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity.

Ozcan L, Wong CC, Li G, Xu T, Pajvani U, Park SK, Wronska A, Chen BX, Marks AR, Fukamizu A, Backs J, Singer HA, Yates JR 3rd, Accili D, Tabas I.

Cell Metab. 2012 May 2;15(5):739-51. doi: 10.1016/j.cmet.2012.03.002. Epub 2012 Apr 12.

2.

Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice.

De Souza CT, Frederico MJ, da Luz G, Cintra DE, Ropelle ER, Pauli JR, Velloso LA.

J Physiol. 2010 Jun 15;588(Pt 12):2239-53. doi: 10.1113/jphysiol.2009.183996. Epub 2010 Apr 26.

3.

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.

Wang Y, Li G, Goode J, Paz JC, Ouyang K, Screaton R, Fischer WH, Chen J, Tabas I, Montminy M.

Nature. 2012 Apr 8;485(7396):128-32. doi: 10.1038/nature10988.

4.

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

Cao W, Collins QF, Becker TC, Robidoux J, Lupo EG Jr, Xiong Y, Daniel KW, Floering L, Collins S.

J Biol Chem. 2005 Dec 30;280(52):42731-7. Epub 2005 Nov 3.

5.

Suppression of hepatic glucose production by human neutrophil alpha-defensins through a signaling pathway distinct from insulin.

Liu HY, Collins QF, Moukdar F, Zhuo D, Han J, Hong T, Collins S, Cao W.

J Biol Chem. 2008 May 2;283(18):12056-63. doi: 10.1074/jbc.M801033200. Epub 2008 Mar 17.

6.

CD38-mediated Ca(2+) signaling contributes to glucagon-induced hepatic gluconeogenesis.

Rah SY, Kim UH.

Sci Rep. 2015 Jun 3;5:10741. doi: 10.1038/srep10741.

7.

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.

Lu M, Wan M, Leavens KF, Chu Q, Monks BR, Fernandez S, Ahima RS, Ueki K, Kahn CR, Birnbaum MJ.

Nat Med. 2012 Feb 19;18(3):388-95. doi: 10.1038/nm.2686.

8.

FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression.

Zhang W, Patil S, Chauhan B, Guo S, Powell DR, Le J, Klotsas A, Matika R, Xiao X, Franks R, Heidenreich KA, Sajan MP, Farese RV, Stolz DB, Tso P, Koo SH, Montminy M, Unterman TG.

J Biol Chem. 2006 Apr 14;281(15):10105-17. Epub 2006 Feb 21.

9.

Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.

Liu TY, Shi CX, Gao R, Sun HJ, Xiong XQ, Ding L, Chen Q, Li YH, Wang JJ, Kang YM, Zhu GQ.

Clin Sci (Lond). 2015 Nov;129(10):839-50. doi: 10.1042/CS20150009. Epub 2015 Jul 13.

PMID:
26201094
10.

Regulation of glucose metabolism via hepatic forkhead transcription factor 1 (FoxO1) by Morinda citrifolia (noni) in high-fat diet-induced obese mice.

Nerurkar PV, Nishioka A, Eck PO, Johns LM, Volper E, Nerurkar VR.

Br J Nutr. 2012 Jul;108(2):218-28. doi: 10.1017/S0007114511005563. Epub 2011 Oct 20.

11.

Mapping MKP-3/FOXO1 interaction and evaluating the effect on gluconeogenesis.

Jiao P, Feng B, Xu H.

PLoS One. 2012;7(7):e41168. doi: 10.1371/journal.pone.0041168. Epub 2012 Jul 25.

12.

Inhibition of gluconeogenesis in primary hepatocytes by stromal cell-derived factor-1 (SDF-1) through a c-Src/Akt-dependent signaling pathway.

Liu HY, Wen GB, Han J, Hong T, Zhuo D, Liu Z, Cao W.

J Biol Chem. 2008 Nov 7;283(45):30642-9. doi: 10.1074/jbc.M803698200. Epub 2008 Sep 11.

13.

GdCl3 reduces hyperglycaemia through Akt/FoxO1-induced suppression of hepatic gluconeogenesis in Type 2 diabetic mice.

Wang Q, Wang N, Dong M, Chen F, Li Z, Chen Y.

Clin Sci (Lond). 2014 Jul;127(2):91-100. doi: 10.1042/CS20130670.

PMID:
24444370
14.

Protein arginine methyltransferase 1 regulates hepatic glucose production in a FoxO1-dependent manner.

Choi D, Oh KJ, Han HS, Yoon YS, Jung CY, Kim ST, Koo SH.

Hepatology. 2012 Oct;56(4):1546-56. doi: 10.1002/hep.25809.

PMID:
22532369
15.

Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes.

Naïmi M, Gautier N, Chaussade C, Valverde AM, Accili D, Van Obberghen E.

Endocrinology. 2007 May;148(5):2424-34. Epub 2007 Feb 15. Erratum in: Endocrinology. 2007 Jul;148(7):3517.

PMID:
17303659
16.

Bradykinin inhibits hepatic gluconeogenesis in obese mice.

Barros CC, Haro A, Russo FJ, Schadock I, Almeida SS, Reis FC, Moraes MR, Haidar A, Hirata AE, Mori M, Bacurau RF, Würtele M, Bader M, Pesquero JB, Araujo RC.

Lab Invest. 2012 Oct;92(10):1419-27. doi: 10.1038/labinvest.2012.105. Epub 2012 Aug 6.

17.

InsP3R-Ca(2+) signaling takes center stage in the hormonal regulation of hepatic gluconeogenesis.

Matsumoto M.

Cell Res. 2012 Nov;22(11):1530-2. doi: 10.1038/cr.2012.95. Epub 2012 Jun 19.

18.

Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver.

Matsumoto M, Pocai A, Rossetti L, Depinho RA, Accili D.

Cell Metab. 2007 Sep;6(3):208-16.

19.

TGF-β1/Smad3 Pathway Targets PP2A-AMPK-FoxO1 Signaling to Regulate Hepatic Gluconeogenesis.

Yadav H, Devalaraja S, Chung ST, Rane SG.

J Biol Chem. 2017 Feb 24;292(8):3420-3432. doi: 10.1074/jbc.M116.764910. Epub 2017 Jan 9.

PMID:
28069811
20.

USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy.

Hall JA, Tabata M, Rodgers JT, Puigserver P.

Mol Endocrinol. 2014 Jun;28(6):912-24. doi: 10.1210/me.2013-1420. Epub 2014 Apr 2.

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