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Items: 1 to 20 of 90


Serpin-derived peptides are antiangiogenic and suppress breast tumor xenograft growth.

Koskimaki JE, Rosca EV, Rivera CG, Lee E, Chen W, Pandey NB, Popel AS.

Transl Oncol. 2012 Apr;5(2):92-7. Epub 2012 Apr 1.


Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer.

Filleur S, Volz K, Nelius T, Mirochnik Y, Huang H, Zaichuk TA, Aymerich MS, Becerra SP, Yap R, Veliceasa D, Shroff EH, Volpert OV.

Cancer Res. 2005 Jun 15;65(12):5144-52.


Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents.

Konson A, Pradeep S, Seger R.

Cancer Res. 2010 Aug 1;70(15):6247-57. doi: 10.1158/0008-5472.CAN-10-0434. Epub 2010 Jul 7.


Effects of human recombinant PEDF protein and PEDF-derived peptide 34-mer on choroidal neovascularization.

Amaral J, Becerra SP.

Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1318-26. doi: 10.1167/iovs.09-4455. Epub 2009 Oct 22.


Short pigment epithelial-derived factor-derived peptide inhibits angiogenesis and tumor growth.

Mirochnik Y, Aurora A, Schulze-Hoepfner FT, Deabes A, Shifrin V, Beckmann R, Polsky C, Volpert OV.

Clin Cancer Res. 2009 Mar 1;15(5):1655-63. doi: 10.1158/1078-0432.CCR-08-2113. Epub 2009 Feb 17.


Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model.

Koskimaki JE, Karagiannis ED, Tang BC, Hammers H, Watkins DN, Pili R, Popel AS.

BMC Cancer. 2010 Feb 1;10:29. doi: 10.1186/1471-2407-10-29.


Pigment epithelium-derived factor inhibits the growth of human esophageal squamous cell carcinoma by suppressing neovascularization.

Kadoya M, Tamoto E, Shichinohe T, Hirano S.

Hokkaido Igaku Zasshi. 2015 May;90(1):17-29.


Suppression of angiogenesis and tumor growth by adenoviral-mediated gene transfer of pigment epithelium-derived factor.

Wang L, Schmitz V, Perez-Mediavilla A, Izal I, Prieto J, Qian C.

Mol Ther. 2003 Jul;8(1):72-9.


Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest.

Konson A, Pradeep S, D'Acunto CW, Seger R.

J Biol Chem. 2011 Feb 4;286(5):3540-51. doi: 10.1074/jbc.M110.151548. Epub 2010 Nov 8.


Combination of pigment epithelium-derived factor with radiotherapy enhances the antitumor effects on nasopharyngeal carcinoma by downregulating vascular endothelial growth factor expression and angiogenesis.

Xu Z, Fang S, Zuo Y, Zhang Y, Cheng R, Wang Q, Yang Z, Cai W, Ma J, Yang X, Gao G.

Cancer Sci. 2011 Oct;102(10):1789-98. doi: 10.1111/j.1349-7006.2011.02013.x. Epub 2011 Jul 29.


PEDF and 34-mer inhibit angiogenesis in the heart by inducing tip cells apoptosis via up-regulating PPAR-γ to increase surface FasL.

Zhang H, Wei T, Jiang X, Li Z, Cui H, Pan J, Zhuang W, Sun T, Liu Z, Zhang Z, Dong H.

Apoptosis. 2016 Jan;21(1):60-8. doi: 10.1007/s10495-015-1186-1.


Gene transfer of pigment epithelium-derived factor suppresses tumor growth and angiogenesis in a hepatoblastoma xenograft model.

Browne M, Stellmach V, Cornwell M, Chung C, Doll JA, Lee EJ, Jameson JL, Reynolds M, Superina RA, Abramson LP, Crawford SE.

Pediatr Res. 2006 Sep;60(3):282-7. Epub 2006 Jul 20.


PEDF-derived synthetic peptides exhibit antitumor activity in an orthotopic model of human osteosarcoma.

Ek ET, Dass CR, Contreras KG, Choong PF.

J Orthop Res. 2007 Dec;25(12):1671-80.


Adeno-associated virus vector-mediated delivery of pigment epithelium-derived factor restricts neuroblastoma angiogenesis and growth.

Streck CJ, Zhang Y, Zhou J, Ng C, Nathwani AC, Davidoff AM.

J Pediatr Surg. 2005 Jan;40(1):236-43.


Growth suppression of cervical carcinoma by pigment epithelium-derived factor via anti-angiogenesis.

Yang J, Chen S, Huang X, Han J, Wang Q, Shi D, Cheng R, Gao G, Yang X.

Cancer Biol Ther. 2010 Jun 15;9(12):967-74. Epub 2010 Jun 8.


Inhibition of tumor cell surface ATP synthesis by pigment epithelium-derived factor: implications for antitumor activity.

Deshpande M, Notari L, Subramanian P, Notario V, Becerra SP.

Int J Oncol. 2012 Jul;41(1):219-27. doi: 10.3892/ijo.2012.1431. Epub 2012 Apr 10.


Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity.

Meyer C, Notari L, Becerra SP.

J Biol Chem. 2002 Nov 22;277(47):45400-7. Epub 2002 Sep 16.


Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor.

Bernard A, Gao-Li J, Franco CA, Bouceba T, Huet A, Li Z.

J Biol Chem. 2009 Apr 17;284(16):10480-90. doi: 10.1074/jbc.M809259200. Epub 2009 Feb 17.

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