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Items: 1 to 20 of 163

1.

Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics.

Bate N, Gingras AR, Bachir A, Horwitz R, Ye F, Patel B, Goult BT, Critchley DR.

PLoS One. 2012;7(4):e34461. doi: 10.1371/journal.pone.0034461. Epub 2012 Apr 4.

2.

Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.

Kopp PM, Bate N, Hansen TM, Brindle NP, Praekelt U, Debrand E, Coleman S, Mazzeo D, Goult BT, Gingras AR, Pritchard CA, Critchley DR, Monkley SJ.

Eur J Cell Biol. 2010 Sep;89(9):661-73. doi: 10.1016/j.ejcb.2010.05.003.

3.

The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton.

Moes M, Rodius S, Coleman SJ, Monkley SJ, Goormaghtigh E, Tremuth L, Kox C, van der Holst PP, Critchley DR, Kieffer N.

J Biol Chem. 2007 Jun 8;282(23):17280-8. Epub 2007 Apr 11.

4.

Localization of an integrin binding site to the C terminus of talin.

Xing B, Jedsadayanmata A, Lam SC.

J Biol Chem. 2001 Nov 30;276(48):44373-8. Epub 2001 Sep 12.

6.

Control of high affinity interactions in the talin C terminus: how talin domains coordinate protein dynamics in cell adhesions.

Himmel M, Ritter A, Rothemund S, Pauling BV, Rottner K, Gingras AR, Ziegler WH.

J Biol Chem. 2009 May 15;284(20):13832-42. doi: 10.1074/jbc.M900266200. Epub 2009 Mar 11.

7.

Characterization of an actin-binding site within the talin FERM domain.

Lee HS, Bellin RM, Walker DL, Patel B, Powers P, Liu H, Garcia-Alvarez B, de Pereda JM, Liddington RC, Volkmann N, Hanein D, Critchley DR, Robson RM.

J Mol Biol. 2004 Oct 22;343(3):771-84.

PMID:
15465061
8.

Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain.

Yan B, Calderwood DA, Yaspan B, Ginsberg MH.

J Biol Chem. 2001 Jul 27;276(30):28164-70. Epub 2001 May 29.

9.

Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation.

Goult BT, Xu XP, Gingras AR, Swift M, Patel B, Bate N, Kopp PM, Barsukov IL, Critchley DR, Volkmann N, Hanein D.

J Struct Biol. 2013 Oct;184(1):21-32. doi: 10.1016/j.jsb.2013.05.014. Epub 2013 May 30.

10.

Revealing the three dimensional architecture of focal adhesion components to explain Ca2+-mediated turnover of focal adhesions.

Chang SJ, Chen YC, Yang CH, Huang SC, Huang HK, Li CC, Harn HI, Chiu WT.

Biochim Biophys Acta. 2017 Mar;1861(3):624-635. doi: 10.1016/j.bbagen.2017.01.002. Epub 2017 Jan 5.

PMID:
28063985
11.
12.

Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling.

Srivastava J, Barreiro G, Groscurth S, Gingras AR, Goult BT, Critchley DR, Kelly MJ, Jacobson MP, Barber DL.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14436-41. doi: 10.1073/pnas.0805163105. Epub 2008 Sep 9.

13.

Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration.

Huang C, Rajfur Z, Yousefi N, Chen Z, Jacobson K, Ginsberg MH.

Nat Cell Biol. 2009 May;11(5):624-30. doi: 10.1038/ncb1868. Epub 2009 Apr 12.

14.

Distinct developmental roles for direct and indirect talin-mediated linkage to actin.

Franco-Cea A, Ellis SJ, Fairchild MJ, Yuan L, Cheung TY, Tanentzapf G.

Dev Biol. 2010 Sep 1;345(1):64-77. doi: 10.1016/j.ydbio.2010.06.027. Epub 2010 Jun 28.

15.

Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin.

Cohen DM, Chen H, Johnson RP, Choudhury B, Craig SW.

J Biol Chem. 2005 Apr 29;280(17):17109-17. Epub 2005 Feb 22.

16.

A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain.

Tremuth L, Kreis S, Melchior C, Hoebeke J, Rondé P, Plançon S, Takeda K, Kieffer N.

J Biol Chem. 2004 May 21;279(21):22258-66. Epub 2004 Mar 18.

17.

Integrin connections to the cytoskeleton through talin and vinculin.

Ziegler WH, Gingras AR, Critchley DR, Emsley J.

Biochem Soc Trans. 2008 Apr;36(Pt 2):235-9. doi: 10.1042/BST0360235. Review.

PMID:
18363566
19.

Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation.

Sun Z, Tseng HY, Tan S, Senger F, Kurzawa L, Dedden D, Mizuno N, Wasik AA, Thery M, Dunn AR, Fässler R.

Nat Cell Biol. 2016 Sep;18(9):941-53. doi: 10.1038/ncb3402. Epub 2016 Aug 22.

PMID:
27548916
20.

The conserved C-terminal I/LWEQ module targets Talin1 to focal adhesions.

Franco SJ, Senetar MA, Simonson WT, Huttenlocher A, McCann RO.

Cell Motil Cytoskeleton. 2006 Sep;63(9):563-81.

PMID:
16830345

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