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CD44 participates in IP-10 induction in cells in which hepatitis C virus RNA is replicating, through an interaction with Toll-like receptor 2 and hyaluronan.

Abe T, Fukuhara T, Wen X, Ninomiya A, Moriishi K, Maehara Y, Takeuchi O, Kawai T, Akira S, Matsuura Y.

J Virol. 2012 Jun;86(11):6159-70. doi: 10.1128/JVI.06872-11. Epub 2012 Apr 4.


Expression of the CXCR3 ligand I-TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation.

Helbig KJ, Ruszkiewicz A, Semendric L, Harley HA, McColl SR, Beard MR.

Hepatology. 2004 May;39(5):1220-9.


Expression of the chemokine IP-10 (CXCL10) by hepatocytes in chronic hepatitis C virus infection correlates with histological severity and lobular inflammation.

Harvey CE, Post JJ, Palladinetti P, Freeman AJ, Ffrench RA, Kumar RK, Marinos G, Lloyd AR.

J Leukoc Biol. 2003 Sep;74(3):360-9.


The Tat protein of human immunodeficiency virus-1 enhances hepatitis C virus replication through interferon gamma-inducible protein-10.

Qu J, Zhang Q, Li Y, Liu W, Chen L, Zhu Y, Wu J.

BMC Immunol. 2012 Apr 3;13:15. doi: 10.1186/1471-2172-13-15.


Toll-like receptor 2 (TLR2), transforming growth factor-β, hyaluronan (HA), and receptor for HA-mediated motility (RHAMM) are required for surfactant protein A-stimulated macrophage chemotaxis.

Foley JP, Lam D, Jiang H, Liao J, Cheong N, McDevitt TM, Zaman A, Wright JR, Savani RC.

J Biol Chem. 2012 Oct 26;287(44):37406-19. doi: 10.1074/jbc.M112.360982. Epub 2012 Sep 4.


CD40 inhibits replication of hepatitis C virus in primary human hepatocytes by c-Jun N terminal kinase activation independent from the interferon pathway.

Rau SJ, Hildt E, Himmelsbach K, Thimme R, Wakita T, Blum HE, Fischer R.

Hepatology. 2013 Jan;57(1):23-36. doi: 10.1002/hep.25966.


Impaired cytokine response in myeloid dendritic cells in chronic hepatitis C virus infection regardless of enhanced expression of Toll-like receptors and retinoic acid inducible gene-I.

Miyazaki M, Kanto T, Inoue M, Itose I, Miyatake H, Sakakibara M, Yakushijin T, Kakita N, Hiramatsu N, Takehara T, Kasahara A, Hayashi N.

J Med Virol. 2008 Jun;80(6):980-8. doi: 10.1002/jmv.21174.


Differential expression of the CXCR3 ligands in chronic hepatitis C virus (HCV) infection and their modulation by HCV in vitro.

Helbig KJ, Ruszkiewicz A, Lanford RE, Berzsenyi MD, Harley HA, McColl SR, Beard MR.

J Virol. 2009 Jan;83(2):836-46. doi: 10.1128/JVI.01388-08. Epub 2008 Nov 5.


Role of Toll-like receptor 2 in the immune response against hepadnaviral infection.

Zhang X, Ma Z, Liu H, Liu J, Meng Z, Broering R, Yang D, Schlaak JF, Roggendorf M, Lu M.

J Hepatol. 2012 Sep;57(3):522-8. doi: 10.1016/j.jhep.2012.05.004. Epub 2012 May 19.


Hepatitis C virus core protein induces homotolerance and cross-tolerance to Toll-like receptor ligands by activation of Toll-like receptor 2.

Chung H, Watanabe T, Kudo M, Chiba T.

J Infect Dis. 2010 Sep 15;202(6):853-61. doi: 10.1086/655812.


Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesion.

Mohamadzadeh M, DeGrendele H, Arizpe H, Estess P, Siegelman M.

J Clin Invest. 1998 Jan 1;101(1):97-108.


Visualization and measurement of ATP levels in living cells replicating hepatitis C virus genome RNA.

Ando T, Imamura H, Suzuki R, Aizaki H, Watanabe T, Wakita T, Suzuki T.

PLoS Pathog. 2012;8(3):e1002561. doi: 10.1371/journal.ppat.1002561. Epub 2012 Mar 1.


Hyaluronan fragments synergize with interferon-gamma to induce the C-X-C chemokines mig and interferon-inducible protein-10 in mouse macrophages.

Horton MR, McKee CM, Bao C, Liao F, Farber JM, Hodge-DuFour J, Puré E, Oliver BL, Wright TM, Noble PW.

J Biol Chem. 1998 Dec 25;273(52):35088-94.


Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54.

Lisignoli G, Cristino S, Piacentini A, Cavallo C, Caplan AI, Facchini A.

J Cell Physiol. 2006 May;207(2):364-73.


Adenosine A2A receptor activation and hyaluronan fragment inhibition reduce inflammation in mouse articular chondrocytes stimulated with interleukin-1β.

Campo GM, Avenoso A, D'Ascola A, Scuruchi M, Prestipino V, Nastasi G, Calatroni A, Campo S.

FEBS J. 2012 Jun;279(12):2120-33. doi: 10.1111/j.1742-4658.2012.08598.x. Epub 2012 May 9.

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