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Items: 1 to 20 of 173

1.

Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress.

Xiao N, Jani K, Morgan K, Okabe R, Cullen DE, Jesneck JL, Raffel GD.

Blood. 2012 May 24;119(21):4898-907. doi: 10.1182/blood-2012-01-403089. Epub 2012 Apr 6.

2.

Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl.

Xiao N, Laha S, Das SP, Morlock K, Jesneck JL, Raffel GD.

Blood. 2015 Feb 5;125(6):941-8. doi: 10.1182/blood-2014-08-593392. Epub 2014 Dec 2.

3.

Thioredoxin-interacting protein regulates hematopoietic stem cell quiescence and mobilization under stress conditions.

Jeong M, Piao ZH, Kim MS, Lee SH, Yun S, Sun HN, Yoon SR, Chung JW, Kim TD, Jeon JH, Lee J, Kim HN, Choi JY, Choi I.

J Immunol. 2009 Aug 15;183(4):2495-505. doi: 10.4049/jimmunol.0804221. Epub 2009 Jul 22.

4.

Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells.

Taniguchi Ishikawa E, Gonzalez-Nieto D, Ghiaur G, Dunn SK, Ficker AM, Murali B, Madhu M, Gutstein DE, Fishman GI, Barrio LC, Cancelas JA.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9071-6. doi: 10.1073/pnas.1120358109. Epub 2012 May 18.

5.

Ott1(Rbm15) has pleiotropic roles in hematopoietic development.

Raffel GD, Mercher T, Shigematsu H, Williams IR, Cullen DE, Akashi K, Bernard OA, Gilliland DG.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6001-6. Epub 2007 Mar 21.

6.

p19 INK4d controls hematopoietic stem cells in a cell-autonomous manner during genotoxic stress and through the microenvironment during aging.

Hilpert M, Legrand C, Bluteau D, Balayn N, Betems A, Bluteau O, Villeval JL, Louache F, Gonin P, Debili N, Plo I, Vainchenker W, Gilles L, Raslova H.

Stem Cell Reports. 2014 Dec 9;3(6):1085-102. doi: 10.1016/j.stemcr.2014.10.005. Epub 2014 Nov 20.

7.

Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.

Jones M, Chase J, Brinkmeier M, Xu J, Weinberg DN, Schira J, Friedman A, Malek S, Grembecka J, Cierpicki T, Dou Y, Camper SA, Maillard I.

J Clin Invest. 2015 May;125(5):2007-20. doi: 10.1172/JCI78124. Epub 2015 Apr 13.

8.

Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells.

Zhang Y, Yan X, Sashida G, Zhao X, Rao Y, Goyama S, Whitman SP, Zorko N, Bernot K, Conway RM, Witte D, Wang QF, Tenen DG, Xiao Z, Marcucci G, Mulloy JC, Grimes HL, Caligiuri MA, Huang G.

Blood. 2012 Aug 2;120(5):1118-29. doi: 10.1182/blood-2012-02-412379. Epub 2012 Jun 26.

9.

Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement.

Wang Z, Li G, Tse W, Bunting KD.

Blood. 2009 May 14;113(20):4856-65. doi: 10.1182/blood-2008-09-181107. Epub 2009 Mar 3.

10.

High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias.

Shin JY, Hu W, Naramura M, Park CY.

J Exp Med. 2014 Feb 10;211(2):217-31. doi: 10.1084/jem.20131128. Epub 2014 Jan 20.

11.

Loss of Sfrp2 in the Niche Amplifies Stress-Induced Cellular Responses, and Impairs the In Vivo Regeneration of the Hematopoietic Stem Cell Pool.

Ruf F, Schreck C, Wagner A, Grziwok S, Pagel C, Romero S, Kieslinger M, Shimono A, Peschel C, Götze KS, Istvanffy R, Oostendorp RA.

Stem Cells. 2016 Sep;34(9):2381-92. doi: 10.1002/stem.2416. Epub 2016 Jun 30.

12.

Slug deficiency enhances self-renewal of hematopoietic stem cells during hematopoietic regeneration.

Sun Y, Shao L, Bai H, Wang ZZ, Wu WS.

Blood. 2010 Mar 4;115(9):1709-17. doi: 10.1182/blood-2009-07-232934. Epub 2009 Dec 23.

13.

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.

Juntilla MM, Patil VD, Calamito M, Joshi RP, Birnbaum MJ, Koretzky GA.

Blood. 2010 May 20;115(20):4030-8. doi: 10.1182/blood-2009-09-241000. Epub 2010 Mar 30.

14.

The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche.

Luo B, Lam BS, Lee SH, Wey S, Zhou H, Wang M, Chen SY, Adams GB, Lee AS.

PLoS One. 2011;6(5):e20364. doi: 10.1371/journal.pone.0020364. Epub 2011 May 24.

15.

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates.

Passegué E, Wagers AJ, Giuriato S, Anderson WC, Weissman IL.

J Exp Med. 2005 Dec 5;202(11):1599-611.

16.

Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells.

Brun AC, Björnsson JM, Magnusson M, Larsson N, Leveén P, Ehinger M, Nilsson E, Karlsson S.

Blood. 2004 Jun 1;103(11):4126-33. Epub 2004 Feb 12.

17.

Smurf2 regulates hematopoietic stem cell self-renewal and aging.

Ramkumar C, Kong Y, Trabucco SE, Gerstein RM, Zhang H.

Aging Cell. 2014 Jun;13(3):478-86. doi: 10.1111/acel.12195. Epub 2014 Feb 4.

18.

Regulation of murine hematopoietic stem cell quiescence by Dmtf1.

Kobayashi M, Srour EF.

Blood. 2011 Dec 15;118(25):6562-71. doi: 10.1182/blood-2011-05-349084. Epub 2011 Oct 28.

19.

Alcam regulates long-term hematopoietic stem cell engraftment and self-renewal.

Jeannet R, Cai Q, Liu H, Vu H, Kuo YH.

Stem Cells. 2013 Mar;31(3):560-71. doi: 10.1002/stem.1309.

20.

Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice.

Ng AP, Loughran SJ, Metcalf D, Hyland CD, de Graaf CA, Hu Y, Smyth GK, Hilton DJ, Kile BT, Alexander WS.

Blood. 2011 Sep 1;118(9):2454-61. doi: 10.1182/blood-2011-03-344739. Epub 2011 Jun 14.

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