Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 94


Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog-Gli1 pathway.

Zhang L, Li L, Jiao M, Wu D, Wu K, Li X, Zhu G, Yang L, Wang X, Hsieh JT, He D.

Cancer Lett. 2012 Oct 1;323(1):48-57. doi: 10.1016/j.canlet.2012.03.037. Epub 2012 Apr 3.


Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway.

Fan P, Fan S, Wang H, Mao J, Shi Y, Ibrahim MM, Ma W, Yu X, Hou Z, Wang B, Li L.

Stem Cell Res Ther. 2013;4(6):146.


Tumorspheres derived from prostate cancer cells possess chemoresistant and cancer stem cell properties.

Zhang L, Jiao M, Li L, Wu D, Wu K, Li X, Zhu G, Dang Q, Wang X, Hsieh JT, He D.

J Cancer Res Clin Oncol. 2012 Apr;138(4):675-86. doi: 10.1007/s00432-011-1146-2. Epub 2012 Jan 12.


Genistein attenuates cancer stem cell characteristics in gastric cancer through the downregulation of Gli1.

Yu D, Shin HS, Lee YS, Lee D, Kim S, Lee YC.

Oncol Rep. 2014 Feb;31(2):673-8. doi: 10.3892/or.2013.2893. Epub 2013 Dec 2.


Inhibition of prostaglandin synthesis and actions by genistein in human prostate cancer cells and by soy isoflavones in prostate cancer patients.

Swami S, Krishnan AV, Moreno J, Bhattacharyya RS, Gardner C, Brooks JD, Peehl DM, Feldman D.

Int J Cancer. 2009 May 1;124(9):2050-9. doi: 10.1002/ijc.24161.


Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway.

Li SH, Fu J, Watkins DN, Srivastava RK, Shankar S.

Mol Cell Biochem. 2013 Jan;373(1-2):217-27. doi: 10.1007/s11010-012-1493-6. Epub 2012 Nov 6.


A novel anti-cancer effect of genistein: reversal of epithelial mesenchymal transition in prostate cancer cells.

Zhang LL, Li L, Wu DP, Fan JH, Li X, Wu KJ, Wang XY, He DL.

Acta Pharmacol Sin. 2008 Sep;29(9):1060-8. doi: 10.1111/j.1745-7254.2008.00831.x.


Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines.

Yao J, An Y, Wie JS, Ji ZL, Lu ZP, Wu JL, Jiang KR, Chen P, Xu ZK, Miao Y.

Swiss Med Wkly. 2011 May 31;141:w13208. doi: 10.4414/smw.2011.13208.


Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer.

Sanchez P, Clement V, Ruiz i Altaba A.

Cancer Res. 2005 Apr 15;65(8):2990-2. Review.


Silibinin inhibits β-catenin/ZEB1 signaling and suppresses bladder cancer metastasis via dual-blocking epithelial-mesenchymal transition and stemness.

Wu K, Ning Z, Zeng J, Fan J, Zhou J, Zhang T, Zhang L, Chen Y, Gao Y, Wang B, Guo P, Li L, Wang X, He D.

Cell Signal. 2013 Dec;25(12):2625-33. doi: 10.1016/j.cellsig.2013.08.028. Epub 2013 Sep 4.


Sonic hedgehog and androgen signaling in tumor and stromal compartments drives epithelial-mesenchymal transition in prostate cancer.

Yamamichi F, Shigemura K, Behnsawy HM, Meligy FY, Huang WC, Li X, Yamanaka K, Hanioka K, Miyake H, Tanaka K, Kawabata M, Shirakawa T, Fujisawa M.

Scand J Urol. 2014 Dec;48(6):523-32. doi: 10.3109/21681805.2014.898336. Epub 2014 Mar 19.


A concentrated aglycone isoflavone preparation (GCP) that demonstrates potent anti-prostate cancer activity in vitro and in vivo.

Bemis DL, Capodice JL, Desai M, Buttyan R, Katz AE.

Clin Cancer Res. 2004 Aug 1;10(15):5282-92.


SOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.

Deng W, Vanderbilt DB, Lin CC, Martin KH, Brundage KM, Ruppert JM.

J Cell Sci. 2015 Mar 15;128(6):1123-38. doi: 10.1242/jcs.162164. Epub 2015 Jan 27.


[Hedgehog signaling pathway activates in gastric carcinoma and promotes the proliferation through GLI1 in MKN28 cell].

Li XW, Li JF, Qu Y, Cai Q, Ji J, Nie H, Chen XH, Zhu ZG, Liu BY.

Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Nov;12(6):603-6. Chinese.


Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model.

Chang HH, Chen BY, Wu CY, Tsao ZJ, Chen YY, Chang CP, Yang CR, Lin DP.

J Biomed Sci. 2011 Jan 18;18:6. doi: 10.1186/1423-0127-18-6.


Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer.

Slusarz A, Shenouda NS, Sakla MS, Drenkhahn SK, Narula AS, MacDonald RS, Besch-Williford CL, Lubahn DB.

Cancer Res. 2010 Apr 15;70(8):3382-90. doi: 10.1158/0008-5472.CAN-09-3012.


Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner.

Lei J, Ma J, Ma Q, Li X, Liu H, Xu Q, Duan W, Sun Q, Xu J, Wu Z, Wu E.

Mol Cancer. 2013 Jun 20;12:66. doi: 10.1186/1476-4598-12-66.


Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer.

Song Z, Yue W, Wei B, Wang N, Li T, Guan L, Shi S, Zeng Q, Pei X, Chen L.

PLoS One. 2011 Mar 4;6(3):e17687. doi: 10.1371/journal.pone.0017687.


Supplemental Content

Support Center