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Items: 1 to 20 of 90

1.

Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.

Valdez PA, Vithayathil PJ, Janelsins BM, Shaffer AL, Williamson PR, Datta SK.

Immunity. 2012 Apr 20;36(4):668-79. doi: 10.1016/j.immuni.2012.02.013. Epub 2012 Mar 29.

2.

Mesenchymal stem cell inhibition of T-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor.

Duffy MM, Pindjakova J, Hanley SA, McCarthy C, Weidhofer GA, Sweeney EM, English K, Shaw G, Murphy JM, Barry FP, Mahon BP, Belton O, Ceredig R, Griffin MD.

Eur J Immunol. 2011 Oct;41(10):2840-51. doi: 10.1002/eji.201141499. Epub 2011 Aug 30.

3.
4.

Unlike αβ T cells, γδ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22.

Raifer H, Mahiny AJ, Bollig N, Petermann F, Hellhund A, Kellner K, Guralnik A, Reinhard K, Bothur E, Huber M, Bauer S, Löhning M, Kiss EA, Ganal SC, Diefenbach A, Korn T, Lohoff M.

Eur J Immunol. 2012 Dec;42(12):3189-201. doi: 10.1002/eji.201142155. Epub 2012 Oct 17.

5.

IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation.

Persson EK, Uronen-Hansson H, Semmrich M, Rivollier A, Hägerbrand K, Marsal J, Gudjonsson S, Håkansson U, Reizis B, Kotarsky K, Agace WW.

Immunity. 2013 May 23;38(5):958-69. doi: 10.1016/j.immuni.2013.03.009. Epub 2013 May 9.

6.

Synovial fibroblasts directly induce Th17 pathogenicity via the cyclooxygenase/prostaglandin E2 pathway, independent of IL-23.

Paulissen SM, van Hamburg JP, Davelaar N, Asmawidjaja PS, Hazes JM, Lubberts E.

J Immunol. 2013 Aug 1;191(3):1364-72. doi: 10.4049/jimmunol.1300274. Epub 2013 Jul 1.

7.

Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation.

Tatara R, Ozaki K, Kikuchi Y, Hatanaka K, Oh I, Meguro A, Matsu H, Sato K, Ozawa K.

Cytotherapy. 2011 Jul;13(6):686-94. doi: 10.3109/14653249.2010.542456. Epub 2010 Dec 20.

PMID:
21171824
8.

Prostaglandin E2-dependent IL-23 production in aged murine dendritic cells.

Myer RG, El Mezayen R, High KP.

Exp Gerontol. 2010 Nov;45(11):834-41. doi: 10.1016/j.exger.2010.06.007. Epub 2010 Jul 1.

9.

Dectin-2 deficiency promotes Th2 response and mucin production in the lungs after pulmonary infection with Cryptococcus neoformans.

Nakamura Y, Sato K, Yamamoto H, Matsumura K, Matsumoto I, Nomura T, Miyasaka T, Ishii K, Kanno E, Tachi M, Yamasaki S, Saijo S, Iwakura Y, Kawakami K.

Infect Immun. 2015 Feb;83(2):671-81. doi: 10.1128/IAI.02835-14. Epub 2014 Nov 24.

10.

The IL17A and IL17F loci have divergent histone modifications and are differentially regulated by prostaglandin E2 in Th17 cells.

Adamik J, Henkel M, Ray A, Auron PE, Duerr R, Barrie A.

Cytokine. 2013 Oct;64(1):404-12. doi: 10.1016/j.cyto.2013.05.010. Epub 2013 Jun 22.

11.

Modulation of autoimmune diseases by interleukin (IL)-17 producing regulatory T helper (Th17) cells.

Singh B, Schwartz JA, Sandrock C, Bellemore SM, Nikoopour E.

Indian J Med Res. 2013 Nov;138(5):591-4. Review.

12.

Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.

Biswas PS, Gupta S, Chang E, Song L, Stirzaker RA, Liao JK, Bhagat G, Pernis AB.

J Clin Invest. 2010 Sep;120(9):3280-95. doi: 10.1172/JCI42856. Epub 2010 Aug 9.

13.

Early growth response gene-2 controls IL-17 expression and Th17 differentiation by negatively regulating Batf.

Miao T, Raymond M, Bhullar P, Ghaffari E, Symonds AL, Meier UC, Giovannoni G, Li S, Wang P.

J Immunol. 2013 Jan 1;190(1):58-65. doi: 10.4049/jimmunol.1200868. Epub 2012 Nov 30.

14.

IL-15-dependent CD8+ CD122+ T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+ T cells.

Yu P, Bamford RN, Waldmann TA.

Eur J Immunol. 2014 Nov;44(11):3330-41. doi: 10.1002/eji.201444675.

15.

Increased Th17 cells in the tumor microenvironment is mediated by IL-23 via tumor-secreted prostaglandin E2.

Qian X, Gu L, Ning H, Zhang Y, Hsueh EC, Fu M, Hu X, Wei L, Hoft DF, Liu J.

J Immunol. 2013 Jun 1;190(11):5894-902. doi: 10.4049/jimmunol.1203141. Epub 2013 May 3.

16.

Restriction of IL-22-producing T cell responses and differential regulation of regulatory T cell compartments by zinc finger transcription factor Ikaros.

Heller JJ, Schjerven H, Li S, Lee A, Qiu J, Chen ZM, Smale ST, Zhou L.

J Immunol. 2014 Oct 15;193(8):3934-46. doi: 10.4049/jimmunol.1401234. Epub 2014 Sep 5.

17.

Cholera toxin directly enhances IL-17A production from human CD4+ T cells.

Tsai HC, Wu R.

J Immunol. 2013 Oct 15;191(8):4095-102. doi: 10.4049/jimmunol.1301079. Epub 2013 Sep 16.

18.

Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf.

Hooper KM, Kong W, Ganea D.

PLoS One. 2017 Jun 12;12(6):e0179184. doi: 10.1371/journal.pone.0179184. eCollection 2017.

19.

Blockade of interleukin-17A protects against coxsackievirus B3-induced myocarditis by increasing COX-2/PGE2 production in the heart.

Xie Y, Chen R, Zhang X, Yu Y, Yang Y, Zou Y, Ge J, Chen H, Garzino-Demo A.

FEMS Immunol Med Microbiol. 2012 Apr;64(3):343-51. doi: 10.1111/j.1574-695X.2011.00918.x. Epub 2011 Dec 22.

20.

Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-β-induced Foxp3 expression.

Ikeda S, Saijo S, Murayama MA, Shimizu K, Akitsu A, Iwakura Y.

J Immunol. 2014 Feb 15;192(4):1449-58. doi: 10.4049/jimmunol.1300387. Epub 2014 Jan 15.

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