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Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study.

Pikula A, Beiser AS, DeCarli C, Himali JJ, Debette S, Au R, Selhub J, Toffler GH, Wang TJ, Meigs JB, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S.

Circulation. 2012 May 1;125(17):2100-7. doi: 10.1161/CIRCULATIONAHA.110.989145. Epub 2012 Mar 28.


Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke.

Andersson C, Preis SR, Beiser A, DeCarli C, Wollert KC, Wang TJ, Januzzi JL Jr, Vasan RS, Seshadri S.

Stroke. 2015 Sep;46(9):2568-75. doi: 10.1161/STROKEAHA.115.009026. Epub 2015 Jul 28.


Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study.

Nayor M, Enserro DM, Beiser AS, Cheng S, DeCarli C, Vasan RS, Seshadri S.

Stroke. 2016 Feb;47(2):383-9. doi: 10.1161/STROKEAHA.115.010405. Epub 2015 Dec 22.


Multimarker approach for the prediction of heart failure incidence in the community.

Velagaleti RS, Gona P, Larson MG, Wang TJ, Levy D, Benjamin EJ, Selhub J, Jacques PF, Meigs JB, Tofler GH, Vasan RS.

Circulation. 2010 Oct 26;122(17):1700-6. doi: 10.1161/CIRCULATIONAHA.109.929661. Epub 2010 Oct 11.


Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study.

Pikula A, Beiser AS, Chen TC, Preis SR, Vorgias D, DeCarli C, Au R, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S.

Stroke. 2013 Oct;44(10):2768-75. doi: 10.1161/STROKEAHA.113.001447. Epub 2013 Aug 8.


Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study.

Seshadri S, Wolf PA, Beiser AS, Selhub J, Au R, Jacques PF, Yoshita M, Rosenberg IH, D'Agostino RB, DeCarli C.

Arch Neurol. 2008 May;65(5):642-9. doi: 10.1001/archneur.65.5.642.


Biomarkers and mortality after transient ischemic attack and minor ischemic stroke: population-based study.

Greisenegger S, Segal HC, Burgess AI, Poole DL, Mehta Z, Rothwell PM.

Stroke. 2015 Mar;46(3):659-66. doi: 10.1161/STROKEAHA.114.007624. Epub 2015 Feb 3.


Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community.

Schnabel RB, Larson MG, Yamamoto JF, Sullivan LM, Pencina MJ, Meigs JB, Tofler GH, Selhub J, Jacques PF, Wolf PA, Magnani JW, Ellinor PT, Wang TJ, Levy D, Vasan RS, Benjamin EJ.

Circulation. 2010 Jan 19;121(2):200-7. doi: 10.1161/CIRCULATIONAHA.109.882241. Epub 2010 Jan 4.


Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study.

Shoamanesh A, Preis SR, Beiser AS, Kase CS, Wolf PA, Vasan RS, Benjamin EJ, Seshadri S, Romero JR.

Neurology. 2016 Sep 20;87(12):1206-11. doi: 10.1212/WNL.0000000000003115. Epub 2016 Aug 24.


Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study.

Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF, Fox CS, Meigs JB, Levy D, Larson MG, Selhub J, D'Agostino RB Sr, Wang TJ, Vasan RS.

Circulation. 2007 Aug 28;116(9):984-92. Epub 2007 Aug 13.


Multiple biomarkers and the risk of incident hypertension.

Wang TJ, Gona P, Larson MG, Levy D, Benjamin EJ, Tofler GH, Jacques PF, Meigs JB, Rifai N, Selhub J, Robins SJ, Newton-Cheh C, Vasan RS.

Hypertension. 2007 Mar;49(3):432-8. Epub 2007 Jan 22.


N-terminal pro-brain natriuretic peptide, C-reactive protein, and urinary albumin levels as predictors of mortality and cardiovascular events in older adults.

Kistorp C, Raymond I, Pedersen F, Gustafsson F, Faber J, Hildebrandt P.

JAMA. 2005 Apr 6;293(13):1609-16.


Multiple biomarkers for the prediction of first major cardiovascular events and death.

Wang TJ, Gona P, Larson MG, Tofler GH, Levy D, Newton-Cheh C, Jacques PF, Rifai N, Selhub J, Robins SJ, Benjamin EJ, D'Agostino RB, Vasan RS.

N Engl J Med. 2006 Dec 21;355(25):2631-9.


A multi-marker approach to predict incident CKD and microalbuminuria.

Fox CS, Gona P, Larson MG, Selhub J, Tofler G, Hwang SJ, Meigs JB, Levy D, Wang TJ, Jacques PF, Benjamin EJ, Vasan RS.

J Am Soc Nephrol. 2010 Dec;21(12):2143-9. doi: 10.1681/ASN.2010010085. Epub 2010 Oct 21.


Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study.

Pikula A, Böger RH, Beiser AS, Maas R, DeCarli C, Schwedhelm E, Himali JJ, Schulze F, Au R, Kelly-Hayes M, Kase CS, Vasan RS, Wolf PA, Seshadri S.

Stroke. 2009 Sep;40(9):2959-64. doi: 10.1161/STROKEAHA.109.557116. Epub 2009 Jul 30.


Anticardiolipin antibodies and risk of ischemic stroke and transient ischemic attack: the Framingham cohort and offspring study.

Janardhan V, Wolf PA, Kase CS, Massaro JM, D'Agostino RB, Franzblau C, Wilson PW.

Stroke. 2004 Mar;35(3):736-41. Epub 2004 Feb 5.


Copeptin and Long-Term Risk of Recurrent Vascular Events After Transient Ischemic Attack and Ischemic Stroke: Population-Based Study.

Greisenegger S, Segal HC, Burgess AI, Poole DL, Mehta Z, Rothwell PM.

Stroke. 2015 Nov;46(11):3117-23. doi: 10.1161/STROKEAHA.115.011021. Epub 2015 Oct 8.


Multiple biomarkers for mortality prediction in peripheral arterial disease.

Amrock SM, Weitzman M.

Vasc Med. 2016 Apr;21(2):105-12. doi: 10.1177/1358863X15621797. Epub 2016 Jan 13.


Relations of biomarkers representing distinct biological pathways to left ventricular geometry.

Velagaleti RS, Gona P, Levy D, Aragam J, Larson MG, Tofler GH, Lieb W, Wang TJ, Benjamin EJ, Vasan RS.

Circulation. 2008 Nov 25;118(22):2252-8, 5p following 2258. doi: 10.1161/CIRCULATIONAHA.108.817411. Epub 2008 Nov 10.

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