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Items: 1 to 20 of 102

1.

FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure.

Hino S, Sakamoto A, Nagaoka K, Anan K, Wang Y, Mimasu S, Umehara T, Yokoyama S, Kosai K, Nakao M.

Nat Commun. 2012 Mar 27;3:758. doi: 10.1038/ncomms1755.

2.

Regulation of LSD1 histone demethylase activity by its associated factors.

Shi YJ, Matson C, Lan F, Iwase S, Baba T, Shi Y.

Mol Cell. 2005 Sep 16;19(6):857-64.

3.

Regulation of hypoxia responses by flavin adenine dinucleotide-dependent modulation of HIF-1α protein stability.

Yang SJ, Park YS, Cho JH, Moon B, An HJ, Lee JY, Xie Z, Wang Y, Pocalyko D, Lee DC, Sohn HA, Kang M, Kim JY, Kim E, Park KC, Kim JA, Yeom YI.

EMBO J. 2017 Apr 13;36(8):1011-1028. doi: 10.15252/embj.201694408. Epub 2017 Mar 9.

PMID:
28279976
4.

Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability.

Foster CT, Dovey OM, Lezina L, Luo JL, Gant TW, Barlev N, Bradley A, Cowley SM.

Mol Cell Biol. 2010 Oct;30(20):4851-63. doi: 10.1128/MCB.00521-10. Epub 2010 Aug 16.

5.

Histone demethylase LSD1 regulates neural stem cell proliferation.

Sun G, Alzayady K, Stewart R, Ye P, Yang S, Li W, Shi Y.

Mol Cell Biol. 2010 Apr;30(8):1997-2005. doi: 10.1128/MCB.01116-09. Epub 2010 Feb 1.

6.

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.

Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, Gozani O, Cheng X, Shi Y.

Nature. 2007 Aug 9;448(7154):718-22.

7.

LSD1 demethylates histone and non-histone proteins.

Nicholson TB, Chen T.

Epigenetics. 2009 Apr 1;4(3):129-32. Epub 2009 Apr 14.

PMID:
19395867
8.

The LSD1 Family of Histone Demethylases and the Pumilio Posttranscriptional Repressor Function in a Complex Regulatory Feedback Loop.

Miles WO, Lepesant JM, Bourdeaux J, Texier M, Kerenyi MA, Nakakido M, Hamamoto R, Orkin SH, Dyson NJ, Di Stefano L.

Mol Cell Biol. 2015 Dec;35(24):4199-211. doi: 10.1128/MCB.00755-15. Epub 2015 Oct 5.

9.

Histone lysine-specific demethylase 1 (LSD1) protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells.

Liu L, Souto J, Liao W, Jiang Y, Li Y, Nishinakamura R, Huang S, Rosengart T, Yang VW, Schuster M, Ma Y, Yang J.

J Biol Chem. 2013 Nov 29;288(48):34719-28. doi: 10.1074/jbc.M113.506568. Epub 2013 Oct 25.

10.

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription.

Metzger E, Wissmann M, Yin N, Müller JM, Schneider R, Peters AH, Günther T, Buettner R, Schüle R.

Nature. 2005 Sep 15;437(7057):436-9. Epub 2005 Aug 3.

PMID:
16079795
11.

LSD1 promotes oxidative metabolism of white adipose tissue.

Duteil D, Metzger E, Willmann D, Karagianni P, Friedrichs N, Greschik H, Günther T, Buettner R, Talianidis I, Metzger D, Schüle R.

Nat Commun. 2014 Jun 10;5:4093. doi: 10.1038/ncomms5093.

12.

Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells.

Vasilatos SN, Katz TA, Oesterreich S, Wan Y, Davidson NE, Huang Y.

Carcinogenesis. 2013 Jun;34(6):1196-207. doi: 10.1093/carcin/bgt033. Epub 2013 Jan 25.

13.

Structural basis of histone demethylation by LSD1 revealed by suicide inactivation.

Yang M, Culhane JC, Szewczuk LM, Gocke CB, Brautigam CA, Tomchick DR, Machius M, Cole PA, Yu H.

Nat Struct Mol Biol. 2007 Jun;14(6):535-9. Epub 2007 May 27.

PMID:
17529991
14.

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.

Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Shi Y.

Cell. 2004 Dec 29;119(7):941-53.

15.

Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy.

Schulte JH, Lim S, Schramm A, Friedrichs N, Koster J, Versteeg R, Ora I, Pajtler K, Klein-Hitpass L, Kuhfittig-Kulle S, Metzger E, Schüle R, Eggert A, Buettner R, Kirfel J.

Cancer Res. 2009 Mar 1;69(5):2065-71. doi: 10.1158/0008-5472.CAN-08-1735. Epub 2009 Feb 17.

16.

Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine.

Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H.

Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15.

PMID:
17569509
17.

A mechanism-based inactivator for histone demethylase LSD1.

Culhane JC, Szewczuk LM, Liu X, Da G, Marmorstein R, Cole PA.

J Am Chem Soc. 2006 Apr 12;128(14):4536-7.

PMID:
16594666
18.

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.

Wissmann M, Yin N, Müller JM, Greschik H, Fodor BD, Jenuwein T, Vogler C, Schneider R, Günther T, Buettner R, Metzger E, Schüle R.

Nat Cell Biol. 2007 Mar;9(3):347-53. Epub 2007 Feb 4.

PMID:
17277772
19.

Lysine-specific histone demethylase LSD1 and the dynamic control of chromatin.

Rudolph T, Beuch S, Reuter G.

Biol Chem. 2013 Aug;394(8):1019-28. doi: 10.1515/hsz-2013-0119. Review.

PMID:
23612539
20.

Crystal structure of human histone lysine-specific demethylase 1 (LSD1).

Chen Y, Yang Y, Wang F, Wan K, Yamane K, Zhang Y, Lei M.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):13956-61. Epub 2006 Sep 6.

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