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Items: 1 to 20 of 65

1.

Cucurbitacins as inducers of cell death and a rich source of potential anticancer compounds.

Ríos JL, Andújar I, Escandell JM, Giner RM, Recio MC.

Curr Pharm Des. 2012;18(12):1663-76. Review.

PMID:
22443631
2.

Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity.

Cai Y, Fang X, He C, Li P, Xiao F, Wang Y, Chen M.

Am J Chin Med. 2015;43(7):1331-50. doi: 10.1142/S0192415X15500755. Epub 2015 Oct 27.

PMID:
26503558
3.

Cucurbitacin: ancient compound shedding new light on cancer treatment.

Lee DH, Iwanski GB, Thoennissen NH.

ScientificWorldJournal. 2010 Mar 5;10:413-8. doi: 10.1100/tsw.2010.44. Review.

4.

Biological activities and potential molecular targets of cucurbitacins: a focus on cancer.

Chen X, Bao J, Guo J, Ding Q, Lu J, Huang M, Wang Y.

Anticancer Drugs. 2012 Sep;23(8):777-87. doi: 10.1097/CAD.0b013e3283541384. Review.

PMID:
22561419
5.

Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549.

Silva IT, Geller FC, Persich L, Dudek SE, Lang KL, Caro MS, Durán FJ, Schenkel EP, Ludwig S, Simões CM.

Invest New Drugs. 2016 Apr;34(2):139-48. doi: 10.1007/s10637-015-0317-4. Epub 2016 Jan 16.

PMID:
26780083
6.

Huang-lian-jie-du-tang, a traditional Chinese medicine prescription, induces cell-cycle arrest and apoptosis in human liver cancer cells in vitro and in vivo.

Hsu YL, Kuo PL, Tzeng TF, Sung SC, Yen MH, Lin LT, Lin CC.

J Gastroenterol Hepatol. 2008 Jul;23(7 Pt 2):e290-9. doi: 10.1111/j.1440-1746.2008.05390.x. Epub 2008 Jun 3.

PMID:
18522681
7.

Down-regulation of c-Src/EGFR-mediated signaling activation is involved in the honokiol-induced cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells.

Park EJ, Min HY, Chung HJ, Hong JY, Kang YJ, Hung TM, Youn UJ, Kim YS, Bae K, Kang SS, Lee SK.

Cancer Lett. 2009 May 18;277(2):133-40. doi: 10.1016/j.canlet.2008.11.029. Epub 2009 Jan 9.

PMID:
19135778
8.

6-O-Angeloylenolin induced cell-cycle arrest and apoptosis in human nasopharyngeal cancer cells.

Su M, Chung HY, Li Y.

Chem Biol Interact. 2011 Feb 1;189(3):167-76. doi: 10.1016/j.cbi.2010.12.022. Epub 2010 Dec 28.

PMID:
21192922
10.

A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway.

Cao W, Li XQ, Wang X, Fan HT, Zhang XN, Hou Y, Liu SB, Mei QB.

Phytomedicine. 2010 Jul;17(8-9):598-605. doi: 10.1016/j.phymed.2009.12.014. Epub 2010 Jan 25.

PMID:
20092988
11.

Corchorusin-D, a saikosaponin-like compound isolated from Corchorus acutangulus Lam., targets mitochondrial apoptotic pathways in leukemic cell lines (HL-60 and U937).

Mallick S, Ghosh P, Samanta SK, Kinra S, Pal BC, Gomes A, Vedasiromoni JR.

Cancer Chemother Pharmacol. 2010 Sep;66(4):709-19. doi: 10.1007/s00280-009-1214-3. Epub 2009 Dec 24.

PMID:
20033811
13.

Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells.

Kim KH, Seo HS, Choi HS, Choi I, Shin YC, Ko SG.

Arch Pharm Res. 2011 Aug;34(8):1363-72. doi: 10.1007/s12272-011-0817-5. Epub 2011 Sep 11.

PMID:
21910059
14.

Actin-aggregating cucurbitacins from Physocarpus capitatus.

Maloney KN, Fujita M, Eggert US, Schroeder FC, Field CM, Mitchison TJ, Clardy J.

J Nat Prod. 2008 Nov;71(11):1927-9. doi: 10.1021/np8005259. Epub 2008 Oct 29.

15.

Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.

Won SH, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Jung DB, Shin JM, Kwon TR, Yun SM, Lee MH, Choi SH, Lü J, Kim SH.

Biol Pharm Bull. 2010;33(11):1828-34.

16.

Effects of mistletoe (Viscum album L.) extracts Iscador on cell cycle and survival of tumor cells.

Harmsma M, Ummelen M, Dignef W, Tusenius KJ, Ramaekers FC.

Arzneimittelforschung. 2006 Jun;56(6A):474-82.

PMID:
16927529
17.

23,24-Dihydrocucurbitacin B induces G2/M cell-cycle arrest and mitochondria-dependent apoptosis in human breast cancer cells (Bcap37).

Yang L, Wu S, Zhang Q, Liu F, Wu P.

Cancer Lett. 2007 Oct 28;256(2):267-78. Epub 2007 Aug 6.

PMID:
17681423
18.

Epstein-Barr virus-mediated protection against etoposide-induced apoptosis in BJA-B B cell lymphoma cells: role of Bcl-2 and caspase proteins.

Blood A, Edwards CJ, Ishii HH, Pat BK, Bryson G, Sculley TB, Gobe GC.

Arch Virol. 2004 Feb;149(2):289-302. Epub 2003 Nov 4.

PMID:
14745596
19.

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.

Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL.

Cancer Lett. 2008 Jan 18;259(1):82-98. Epub 2007 Nov 19.

PMID:
18023967
20.

Luffa echinata Roxb. induces human colon cancer cell (HT-29) death by triggering the mitochondrial apoptosis pathway.

Shang LH, Li CM, Yang ZY, Che DH, Cao JY, Yu Y.

Molecules. 2012 May 16;17(5):5780-94. doi: 10.3390/molecules17055780.

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