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Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells.

Sage PT, Varghese LM, Martinelli R, Sciuto TE, Kamei M, Dvorak AM, Springer TA, Sharpe AH, Carman CV.

J Immunol. 2012 Apr 15;188(8):3686-99. doi: 10.4049/jimmunol.1102594. Epub 2012 Mar 21.


Differential kinetics of antigen dependency of CD4+ and CD8+ T cells.

Rabenstein H, Behrendt AC, Ellwart JW, Naumann R, Horsch M, Beckers J, Obst R.

J Immunol. 2014 Apr 15;192(8):3507-17. doi: 10.4049/jimmunol.1302725. Epub 2014 Mar 17.


CD8 T cell memory recall is enhanced by novel direct interactions with CD4 T cells enabled by MHC class II transferred from APCs.

Romagnoli PA, Premenko-Lanier MF, Loria GD, Altman JD.

PLoS One. 2013;8(2):e56999. doi: 10.1371/journal.pone.0056999. Epub 2013 Feb 18.


Significant Differences in Antigen-Induced Transendothelial Migration of Human CD8 and CD4 T Effector Memory Cells.

Manes TD, Pober JS.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1910-8. doi: 10.1161/ATVBAHA.116.308039. Epub 2016 Jul 21.


TCR signaling antagonizes rapid IP-10-mediated transendothelial migration of effector memory CD4+ T cells.

Manes TD, Shiao SL, Dengler TJ, Pober JS.

J Immunol. 2007 Mar 1;178(5):3237-43.


Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function.

Kenna TJ, Waldie T, McNally A, Thomson M, Yagita H, Thomas R, Steptoe RJ.

J Immunol. 2010 Jan 15;184(2):598-606. doi: 10.4049/jimmunol.0900032. Epub 2009 Dec 7.


CD4+ Th-APC with acquired peptide/MHC class I and II complexes stimulate type 1 helper CD4+ and central memory CD8+ T cell responses.

Umeshappa CS, Huang H, Xie Y, Wei Y, Mulligan SJ, Deng Y, Xiang J.

J Immunol. 2009 Jan 1;182(1):193-206.


Distinct signal transduction in mouse CD4+ and CD8+ splenic T cells after CD28 receptor ligation.

Abe R, Vandenberghe P, Craighead N, Smoot DS, Lee KP, June CH.

J Immunol. 1995 Feb 1;154(3):985-97.


Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells.

Schildberg FA, Hegenbarth SI, Schumak B, Scholz K, Limmer A, Knolle PA.

Eur J Immunol. 2008 Apr;38(4):957-67. doi: 10.1002/eji.200738060. Erratum in: Eur J Immunol. 2008 Jun;38(6):1767. Scholz, Kai [added].


Induction of IL-4-producing CD4+ T cells by antigenic peptides altered for TCR binding.

Tao X, Grant C, Constant S, Bottomly K.

J Immunol. 1997 May 1;158(9):4237-44.


The brain parenchyma is permissive for full antitumor CTL effector function, even in the absence of CD4 T cells.

Walker PR, Calzascia T, Schnuriger V, Scamuffa N, Saas P, de Tribolet N, Dietrich PY.

J Immunol. 2000 Sep 15;165(6):3128-35.


Cross talk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells.

Li H, Hong S, Qian J, Zheng Y, Yang J, Yi Q.

Blood. 2010 Jul 15;116(2):210-7. doi: 10.1182/blood-2009-11-255026. Epub 2010 Mar 19.

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