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Items: 1 to 20 of 96

1.

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow.

Kim HJ, Huh D, Hamilton G, Ingber DE.

Lab Chip. 2012 Jun 21;12(12):2165-74. doi: 10.1039/c2lc40074j. Epub 2012 Mar 20.

PMID:
22434367
2.

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation.

Kim HJ, Ingber DE.

Integr Biol (Camb). 2013 Sep;5(9):1130-40. doi: 10.1039/c3ib40126j.

PMID:
23817533
3.

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment.

Jang KJ, Mehr AP, Hamilton GA, McPartlin LA, Chung S, Suh KY, Ingber DE.

Integr Biol (Camb). 2013 Sep;5(9):1119-29. doi: 10.1039/c3ib40049b.

PMID:
23644926
4.

A microfluidic cell culture device (μFCCD) to culture epithelial cells with physiological and morphological properties that mimic those of the human intestine.

Chi M, Yi B, Oh S, Park DJ, Sung JH, Park S.

Biomed Microdevices. 2015;17(3):9966. doi: 10.1007/s10544-015-9966-5.

PMID:
26002774
5.

The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine.

Pusch J, Votteler M, Göhler S, Engl J, Hampel M, Walles H, Schenke-Layland K.

Biomaterials. 2011 Oct;32(30):7469-78. doi: 10.1016/j.biomaterials.2011.06.035. Epub 2011 Jul 20.

PMID:
21764120
6.

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device.

Kim HJ, Lee J, Choi JH, Bahinski A, Ingber DE.

J Vis Exp. 2016 Aug 30;(114). doi: 10.3791/54344.

PMID:
27684630
7.

Microfluidic gut-on-a-chip with three-dimensional villi structure.

Shim KY, Lee D, Han J, Nguyen NT, Park S, Sung JH.

Biomed Microdevices. 2017 Jun;19(2):37. doi: 10.1007/s10544-017-0179-y.

PMID:
28451924
8.

Microfabrication of human organs-on-chips.

Huh D, Kim HJ, Fraser JP, Shea DE, Khan M, Bahinski A, Hamilton GA, Ingber DE.

Nat Protoc. 2013 Nov;8(11):2135-57. doi: 10.1038/nprot.2013.137. Epub 2013 Oct 10.

PMID:
24113786
9.

A microfluidic device with 3-d hydrogel villi scaffold to simulate intestinal absorption.

Kim SH, Lee JW, Choi I, Kim YC, Lee JB, Sung JH.

J Nanosci Nanotechnol. 2013 Nov;13(11):7220-8.

PMID:
24245233
10.

Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip.

Kim HJ, Li H, Collins JJ, Ingber DE.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E7-15. doi: 10.1073/pnas.1522193112. Epub 2015 Dec 14.

11.

A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice.

Huh D, Leslie DC, Matthews BD, Fraser JP, Jurek S, Hamilton GA, Thorneloe KS, McAlexander MA, Ingber DE.

Sci Transl Med. 2012 Nov 7;4(159):159ra147. doi: 10.1126/scitranslmed.3004249.

12.

Epithelial NEMO links innate immunity to chronic intestinal inflammation.

Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Neurath MF, Pasparakis M.

Nature. 2007 Mar 29;446(7135):557-61. Epub 2007 Mar 14.

13.

Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro.

Villenave R, Wales SQ, Hamkins-Indik T, Papafragkou E, Weaver JC, Ferrante TC, Bahinski A, Elkins CA, Kulka M, Ingber DE.

PLoS One. 2017 Feb 1;12(2):e0169412. doi: 10.1371/journal.pone.0169412. eCollection 2017.

14.

An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models.

Kimura H, Yamamoto T, Sakai H, Sakai Y, Fujii T.

Lab Chip. 2008 May;8(5):741-6. doi: 10.1039/b717091b. Epub 2008 Apr 4.

PMID:
18432344
15.

Characterization of immunologically active drugs in a novel organotypic co-culture model of the human gut and whole blood.

Schmohl M, Schneiderhan-Marra N, Baur N, Hefner K, Blum M, Stein GM, Joos TO, Schmolz M.

Int Immunopharmacol. 2012 Dec;14(4):722-8. doi: 10.1016/j.intimp.2012.10.010. Epub 2012 Oct 24.

PMID:
23102666
16.

Constitutive and regulated secretion of secretory leukocyte proteinase inhibitor by human intestinal epithelial cells.

Si-Tahar M, Merlin D, Sitaraman S, Madara JL.

Gastroenterology. 2000 Jun;118(6):1061-71.

PMID:
10833481
17.

Adherence and viability of intestinal bacteria to differentiated Caco-2 cells quantified by flow cytometry.

Grootaert C, Boon N, Zeka F, Vanhoecke B, Bracke M, Verstraete W, Van de Wiele T.

J Microbiol Methods. 2011 Jul;86(1):33-41. doi: 10.1016/j.mimet.2011.03.011. Epub 2011 Apr 2.

PMID:
21443910
18.

Glucagon-like peptide 2 improves intestinal wound healing through induction of epithelial cell migration in vitro-evidence for a TGF--beta-mediated effect.

Bulut K, Meier JJ, Ansorge N, Felderbauer P, Schmitz F, Hoffmann P, Schmidt WE, Gallwitz B.

Regul Pept. 2004 Sep 15;121(1-3):137-43.

PMID:
15256284
19.

A three-dimensional coculture of enterocytes, monocytes and dendritic cells to model inflamed intestinal mucosa in vitro.

Leonard F, Collnot EM, Lehr CM.

Mol Pharm. 2010 Dec 6;7(6):2103-19. doi: 10.1021/mp1000795. Epub 2010 Nov 1.

PMID:
20809575
20.

Layer-by-layer microfluidics for biomimetic three-dimensional structures.

Tan W, Desai TA.

Biomaterials. 2004 Mar-Apr;25(7-8):1355-64.

PMID:
14643610

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