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Items: 1 to 20 of 97

1.

Generation of functional insulin-producing cells in the gut by Foxo1 ablation.

Talchai C, Xuan S, Kitamura T, DePinho RA, Accili D.

Nat Genet. 2012 Mar 11;44(4):406-12, S1. doi: 10.1038/ng.2215.

2.

Gut insulin from Foxo1 loss.

Kim SK.

Nat Genet. 2012 Mar 28;44(4):363-4. doi: 10.1038/ng.2226.

PMID:
22456735
3.

FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures.

Bouchi R, Foo KS, Hua H, Tsuchiya K, Ohmura Y, Sandoval PR, Ratner LE, Egli D, Leibel RL, Accili D.

Nat Commun. 2014 Jun 30;5:4242. doi: 10.1038/ncomms5242.

4.

Regulation of pancreatic juxtaductal endocrine cell formation by FoxO1.

Kitamura T, Kitamura YI, Kobayashi M, Kikuchi O, Sasaki T, Depinho RA, Accili D.

Mol Cell Biol. 2009 Aug;29(16):4417-30. doi: 10.1128/MCB.01622-08. Epub 2009 Jun 8.

5.

Apolipoprotein A-I increases insulin secretion and production from pancreatic β-cells via a G-protein-cAMP-PKA-FoxO1-dependent mechanism.

Cochran BJ, Bisoendial RJ, Hou L, Glaros EN, Rossy J, Thomas SR, Barter PJ, Rye KA.

Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2261-7. doi: 10.1161/ATVBAHA.114.304131. Epub 2014 Aug 21.

6.

Effect of forkhead box O1 (FOXO1) on beta cell development in the human fetal pancreas.

Al-Masri M, Krishnamurthy M, Li J, Fellows GF, Dong HH, Goodyer CG, Wang R.

Diabetologia. 2010 Apr;53(4):699-711. doi: 10.1007/s00125-009-1632-0. Epub 2009 Dec 24.

PMID:
20033803
7.

Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function.

Talchai SC, Accili D.

Diabetes. 2015 Aug;64(8):2868-79. doi: 10.2337/db14-1696. Epub 2015 Mar 17.

8.

The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice.

Beucher A, Gjernes E, Collin C, Courtney M, Meunier A, Collombat P, Gradwohl G.

PLoS One. 2012;7(5):e36449. doi: 10.1371/journal.pone.0036449. Epub 2012 May 3.

9.

Engineered enteroendocrine cells secrete insulin in response to glucose and reverse hyperglycemia in diabetic mice.

Han J, Lee HH, Kwon H, Shin S, Yoon JW, Jun HS.

Mol Ther. 2007 Jun;15(6):1195-202. Epub 2007 Feb 13.

10.

Analysis of Foxo1-regulated genes using Foxo1-deficient pancreatic β cells.

Miyazaki S, Minamida R, Furuyama T, Tashiro F, Yamato E, Inagaki S, Miyazaki J.

Genes Cells. 2012 Sep;17(9):758-67. doi: 10.1111/j.1365-2443.2012.01625.x. Epub 2012 Jul 30.

11.

FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells.

Kibbe C, Chen J, Xu G, Jing G, Shalev A.

J Biol Chem. 2013 Aug 9;288(32):23194-202. doi: 10.1074/jbc.M113.473082. Epub 2013 Jun 26.

12.

Regeneration of insulin-producing pancreatic cells using a volatile bioactive compound and human teeth.

Okada M, Imai T, Yaegaki K, Ishkitiev N, Tanaka T.

J Breath Res. 2014 Oct 30;8(4):046004. doi: 10.1088/1752-7155/8/4/046004.

PMID:
25358383
13.

Protective action of liraglutide in beta cells under lipotoxic stress via PI3K/Akt/FoxO1 pathway.

Shao S, Nie M, Chen C, Chen X, Zhang M, Yuan G, Yu X, Yang Y.

J Cell Biochem. 2014 Jun;115(6):1166-75. doi: 10.1002/jcb.24763.

PMID:
24415347
14.

Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure.

Kluth O, Mirhashemi F, Scherneck S, Kaiser D, Kluge R, Neschen S, Joost HG, Schürmann A.

Diabetologia. 2011 Mar;54(3):605-16. doi: 10.1007/s00125-010-1973-8. Epub 2010 Nov 24.

15.

Forkhead Protein FoxO1 Acts as a Repressor to Inhibit Cell Differentiation in Human Fetal Pancreatic Progenitor Cells.

Jiang Z, Tian J, Zhang W, Yan H, Liu L, Huang Z, Lou J, Ma X.

J Diabetes Res. 2017;2017:6726901. doi: 10.1155/2017/6726901. Epub 2017 Feb 28.

16.

Human embryonic stem cell differentiation into insulin secreting β-cells for diabetes.

Bose B, Shenoy SP, Konda S, Wangikar P.

Cell Biol Int. 2012 Nov 1;36(11):1013-20. doi: 10.1042/CBI20120210.

PMID:
22897387
17.

Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance.

Okamoto H, Hribal ML, Lin HV, Bennett WR, Ward A, Accili D.

J Clin Invest. 2006 Mar;116(3):775-82. Epub 2006 Feb 16.

18.

Glucose-dependent insulin release from genetically engineered K cells.

Cheung AT, Dayanandan B, Lewis JT, Korbutt GS, Rajotte RV, Bryer-Ash M, Boylan MO, Wolfe MM, Kieffer TJ.

Science. 2000 Dec 8;290(5498):1959-62.

19.

Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction.

Hennige AM, Ranta F, Heinzelmann I, Düfer M, Michael D, Braumüller H, Lutz SZ, Lammers R, Drews G, Bosch F, Häring HU, Ullrich S.

Diabetes. 2010 Jan;59(1):119-27. doi: 10.2337/db09-0512. Epub 2009 Oct 13.

20.

Peroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation.

Li L, Li T, Zhang Y, Pan Z, Wu B, Huang X, Zhang Y, Mei Y, Ge L, Shen G, Ge RS, Zhu D, Lou Y.

Cell Death Dis. 2015 Apr 9;6:e1715. doi: 10.1038/cddis.2015.88.

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