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Items: 1 to 20 of 107

1.

Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease.

Holtzman DM, Herz J, Bu G.

Cold Spring Harb Perspect Med. 2012 Mar;2(3):a006312. doi: 10.1101/cshperspect.a006312. Review.

2.

Apolipoprotein E in synaptic plasticity and Alzheimer's disease: potential cellular and molecular mechanisms.

Kim J, Yoon H, Basak J, Kim J.

Mol Cells. 2014 Nov;37(11):767-76. doi: 10.14348/molcells.2014.0248. Epub 2014 Oct 30. Review.

3.

Apolipoprotein E isoform-specific effects on lipoprotein receptor processing.

Bachmeier C, Shackleton B, Ojo J, Paris D, Mullan M, Crawford F.

Neuromolecular Med. 2014 Dec;16(4):686-96.

4.

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.

Liu CC, Kanekiyo T, Xu H, Bu G.

Nat Rev Neurol. 2013 Feb;9(2):106-18. doi: 10.1038/nrneurol.2012.263. Epub 2013 Jan 8. Erratum in: Nat Rev Neurol. 2013. doi: 10.1038/nmeurol.2013.32. Liu, Chia-Chan [corrected to Liu, Chia-Chen].

5.

Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways.

O'Callaghan P, Noborn F, Sehlin D, Li JP, Lannfelt L, Lindahl U, Zhang X.

Amyloid. 2014 Jun;21(2):76-87. doi: 10.3109/13506129.2013.879643. Epub 2014 Feb 3.

PMID:
24491019
6.

The role of apolipoprotein E in Alzheimer's disease.

Kim J, Basak JM, Holtzman DM.

Neuron. 2009 Aug 13;63(3):287-303. doi: 10.1016/j.neuron.2009.06.026. Review.

7.

Functional role of lipoprotein receptors in Alzheimer's disease.

Jaeger S, Pietrzik CU.

Curr Alzheimer Res. 2008 Feb;5(1):15-25. Review.

PMID:
18288927
8.

Sortilin, a novel APOE receptor implicated in Alzheimer disease.

Carlo AS.

Prion. 2013 Sep-Oct;7(5):378-82. doi: 10.4161/pri.26746. Epub 2013 Oct 11. Review.

9.

Apolipoprotein E-low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner.

Johnson LA, Olsen RH, Merkens LS, DeBarber A, Steiner RD, Sullivan PM, Maeda N, Raber J.

Neurobiol Dis. 2014 Apr;64:150-62. doi: 10.1016/j.nbd.2013.12.016. Epub 2014 Jan 9.

10.
11.

Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide.

Hashimoto T, Serrano-Pozo A, Hori Y, Adams KW, Takeda S, Banerji AO, Mitani A, Joyner D, Thyssen DH, Bacskai BJ, Frosch MP, Spires-Jones TL, Finn MB, Holtzman DM, Hyman BT.

J Neurosci. 2012 Oct 24;32(43):15181-92. doi: 10.1523/JNEUROSCI.1542-12.2012.

12.

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.

Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM.

Sci Transl Med. 2011 Jun 29;3(89):89ra57. doi: 10.1126/scitranslmed.3002156.

13.

Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.

Pankiewicz JE, Guridi M, Kim J, Asuni AA, Sanchez S, Sullivan PM, Holtzman DM, Sadowski MJ.

Acta Neuropathol Commun. 2014 Jun 28;2:75. doi: 10.1186/s40478-014-0075-0.

14.

Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease.

Martiskainen H, Haapasalo A, Kurkinen KM, Pihlajamäki J, Soininen H, Hiltunen M.

Expert Opin Ther Targets. 2013 Jul;17(7):781-94. doi: 10.1517/14728222.2013.789862. Epub 2013 Apr 11. Review.

PMID:
23573918
15.

Amyloid-β protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer's disease.

Rolyan H, Feike AC, Upadhaya AR, Waha A, Van Dooren T, Haass C, Birkenmeier G, Pietrzik CU, Van Leuven F, Thal DR.

J Neural Transm (Vienna). 2011 May;118(5):699-712. doi: 10.1007/s00702-010-0572-7. Epub 2011 Jan 6.

PMID:
21210284
16.

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy.

Bu G.

Nat Rev Neurosci. 2009 May;10(5):333-44. doi: 10.1038/nrn2620. Epub 2009 Apr 2. Review.

17.

Apolipoprotein E, amyloid-beta, and blood-brain barrier permeability in Alzheimer disease.

Donahue JE, Johanson CE.

J Neuropathol Exp Neurol. 2008 Apr;67(4):261-70. doi: 10.1097/NEN.0b013e31816a0dc8. Review. Erratum in: J Neuropathol Exp Neurol. 2008 Jun;67(6):634.

18.

Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E.

Fan J, Donkin J, Wellington C.

Biofactors. 2009 May-Jun;35(3):239-48. doi: 10.1002/biof.37. Review.

PMID:
19472365
19.

[Role of apolipoprotein E in the molecular pathomechanism of Alzheimer disease].

Michikawa M.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2014 Feb;34(1):5-9. Review. Japanese.

PMID:
25069266
20.

Apolipoprotein E receptor pathways in Alzheimer disease.

Schmidt V, Carlo AS, Willnow TE.

Wiley Interdiscip Rev Syst Biol Med. 2014 May-Jun;6(3):255-70. doi: 10.1002/wsbm.1262. Epub 2014 Mar 6. Review.

PMID:
24604742
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