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Items: 1 to 20 of 104

1.

Topoisomerase I poisoning results in PARP-mediated replication fork reversal.

Ray Chaudhuri A, Hashimoto Y, Herrador R, Neelsen KJ, Fachinetti D, Bermejo R, Cocito A, Costanzo V, Lopes M.

Nat Struct Mol Biol. 2012 Mar 4;19(4):417-23. doi: 10.1038/nsmb.2258.

PMID:
22388737
2.

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.

Berti M, Ray Chaudhuri A, Thangavel S, Gomathinayagam S, Kenig S, Vujanovic M, Odreman F, Glatter T, Graziano S, Mendoza-Maldonado R, Marino F, Lucic B, Biasin V, Gstaiger M, Aebersold R, Sidorova JM, Monnat RJ Jr, Lopes M, Vindigni A.

Nat Struct Mol Biol. 2013 Mar;20(3):347-54. doi: 10.1038/nsmb.2501. Epub 2013 Feb 10.

3.

Topoisomerase degradation, DSB repair, p53 and IAPs in cancer cell resistance to camptothecin-like topoisomerase I inhibitors.

Tomicic MT, Kaina B.

Biochim Biophys Acta. 2013 Jan;1835(1):11-27. doi: 10.1016/j.bbcan.2012.09.002. Epub 2012 Sep 21. Review.

PMID:
23006513
4.

Preferential potentiation of topoisomerase I poison cytotoxicity by PARP inhibition in S phase.

Znojek P, Willmore E, Curtin NJ.

Br J Cancer. 2014 Sep 23;111(7):1319-26. doi: 10.1038/bjc.2014.378. Epub 2014 Jul 8.

5.

Tipin functions in the protection against topoisomerase I inhibitor.

Hosono Y, Abe T, Higuchi M, Kajii K, Sakuraba S, Tada S, Enomoto T, Seki M.

J Biol Chem. 2014 Apr 18;289(16):11374-84. doi: 10.1074/jbc.M113.531707. Epub 2014 Feb 25.

7.

ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.

Jossé R, Martin SE, Guha R, Ormanoglu P, Pfister TD, Reaper PM, Barnes CS, Jones J, Charlton P, Pollard JR, Morris J, Doroshow JH, Pommier Y.

Cancer Res. 2014 Dec 1;74(23):6968-79. doi: 10.1158/0008-5472.CAN-13-3369. Epub 2014 Sep 30.

8.

Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells.

D'Onofrio G, Tramontano F, Dorio AS, Muzi A, Maselli V, Fulgione D, Graziani G, Malanga M, Quesada P.

Biochem Pharmacol. 2011 Jan 15;81(2):194-202. doi: 10.1016/j.bcp.2010.09.019. Epub 2010 Sep 25.

PMID:
20875401
9.

ATP modulates poly(ADP-ribose) polymerase-1-facilitated topoisomerase I-linked DNA religation in the presence of camptothecin.

Park SY, Leung CH, Cheng YC.

Mol Pharmacol. 2008 Jun;73(6):1829-37. doi: 10.1124/mol.107.044438. Epub 2008 Mar 18.

10.

Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system.

Tsao YP, Russo A, Nyamuswa G, Silber R, Liu LF.

Cancer Res. 1993 Dec 15;53(24):5908-14.

PMID:
8261402
11.

Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes.

Regairaz M, Zhang YW, Fu H, Agama KK, Tata N, Agrawal S, Aladjem MI, Pommier Y.

J Cell Biol. 2011 Nov 28;195(5):739-49. doi: 10.1083/jcb.201104003.

12.

Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage.

Vance JR, Wilson TE.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13669-74. Epub 2002 Oct 4.

13.

PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA.

Sugimura K, Takebayashi S, Taguchi H, Takeda S, Okumura K.

J Cell Biol. 2008 Dec 29;183(7):1203-12. doi: 10.1083/jcb.200806068. Epub 2008 Dec 22.

14.

Inhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer Therapy.

Xu Y, Her C.

Biomolecules. 2015 Jul 22;5(3):1652-70. doi: 10.3390/biom5031652. Review.

15.

New Topoisomerase I mutations are associated with resistance to camptothecin.

Gongora C, Vezzio-Vie N, Tuduri S, Denis V, Causse A, Auzanneau C, Collod-Beroud G, Coquelle A, Pasero P, Pourquier P, Martineau P, Del Rio M.

Mol Cancer. 2011 May 27;10:64. doi: 10.1186/1476-4598-10-64.

16.

Protein expression of DNA damage repair proteins dictates response to topoisomerase and PARP inhibitors in triple-negative breast cancer.

Boerner JL, Nechiporchik N, Mueller KL, Polin L, Heilbrun L, Boerner SA, Zoratti GL, Stark K, LoRusso PM, Burger A.

PLoS One. 2015 Mar 16;10(3):e0119614. doi: 10.1371/journal.pone.0119614. eCollection 2015.

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19.

Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells.

Das SK, Rehman I, Ghosh A, Sengupta S, Majumdar P, Jana B, Das BB.

Nucleic Acids Res. 2016 Sep 30;44(17):8363-75. doi: 10.1093/nar/gkw665. Epub 2016 Jul 27.

20.

Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells.

Zellweger R, Dalcher D, Mutreja K, Berti M, Schmid JA, Herrador R, Vindigni A, Lopes M.

J Cell Biol. 2015 Mar 2;208(5):563-79. doi: 10.1083/jcb.201406099.

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