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Items: 1 to 20 of 94

1.

RNA-binding protein HuD controls insulin translation.

Lee EK, Kim W, Tominaga K, Martindale JL, Yang X, Subaran SS, Carlson OD, Mercken EM, Kulkarni RN, Akamatsu W, Okano H, Perrone-Bizzozero NI, de Cabo R, Egan JM, Gorospe M.

Mol Cell. 2012 Mar 30;45(6):826-35. doi: 10.1016/j.molcel.2012.01.016. Epub 2012 Mar 1.

2.

The RNA-binding protein HuD regulates autophagosome formation in pancreatic β cells by promoting autophagy-related gene 5 expression.

Kim C, Kim W, Lee H, Ji E, Choe YJ, Martindale JL, Akamatsu W, Okano H, Kim HS, Nam SW, Gorospe M, Lee EK.

J Biol Chem. 2014 Jan 3;289(1):112-21. doi: 10.1074/jbc.M113.474700. Epub 2013 Nov 25.

3.

RNA-binding protein HuD reduces triglyceride production in pancreatic β cells by enhancing the expression of insulin-induced gene 1.

Kim C, Lee H, Kang H, Shin JJ, Tak H, Kim W, Gorospe M, Lee EK.

Biochim Biophys Acta. 2016 Apr;1859(4):675-85. doi: 10.1016/j.bbagrm.2016.02.017. Epub 2016 Mar 3.

PMID:
26945853
4.

miR-375 inhibits differentiation of neurites by lowering HuD levels.

Abdelmohsen K, Hutchison ER, Lee EK, Kuwano Y, Kim MM, Masuda K, Srikantan S, Subaran SS, Marasa BS, Mattson MP, Gorospe M.

Mol Cell Biol. 2010 Sep;30(17):4197-210. doi: 10.1128/MCB.00316-10. Epub 2010 Jun 28.

5.

HuD stimulates translation via eIF4A.

Chen CY, Shyu AB.

Mol Cell. 2009 Dec 25;36(6):920-1. doi: 10.1016/j.molcel.2009.12.013.

6.

Alterations in mossy fiber physiology and GAP-43 expression and function in transgenic mice overexpressing HuD.

Tanner DC, Qiu S, Bolognani F, Partridge LD, Weeber EJ, Perrone-Bizzozero NI.

Hippocampus. 2008;18(8):814-23. doi: 10.1002/hipo.20442.

7.

HuD regulates coding and noncoding RNA to induce APP→Aβ processing.

Kang MJ, Abdelmohsen K, Hutchison ER, Mitchell SJ, Grammatikakis I, Guo R, Noh JH, Martindale JL, Yang X, Lee EK, Faghihi MA, Wahlestedt C, Troncoso JC, Pletnikova O, Perrone-Bizzozero N, Resnick SM, de Cabo R, Mattson MP, Gorospe M.

Cell Rep. 2014 Jun 12;7(5):1401-9. doi: 10.1016/j.celrep.2014.04.050. Epub 2014 May 22.

8.

Degradation of high affinity HuD targets releases Kv1.1 mRNA from miR-129 repression by mTORC1.

Sosanya NM, Huang PP, Cacheaux LP, Chen CJ, Nguyen K, Perrone-Bizzozero NI, Raab-Graham KF.

J Cell Biol. 2013 Jul 8;202(1):53-69. doi: 10.1083/jcb.201212089.

9.

Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction.

Bronicki LM, Jasmin BJ.

RNA. 2013 Aug;19(8):1019-37. doi: 10.1261/rna.039164.113. Review.

10.

Glucose-stimulated translation regulation of insulin by the 5' UTR-binding proteins.

Kulkarni SD, Muralidharan B, Panda AC, Bakthavachalu B, Vindu A, Seshadri V.

J Biol Chem. 2011 Apr 22;286(16):14146-56. doi: 10.1074/jbc.M110.190553. Epub 2011 Feb 28.

11.

Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation.

Wicksteed B, Herbert TP, Alarcon C, Lingohr MK, Moss LG, Rhodes CJ.

J Biol Chem. 2001 Jun 22;276(25):22553-8. Epub 2001 Apr 10.

12.

Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits.

Akten B, Kye MJ, Hao le T, Wertz MH, Singh S, Nie D, Huang J, Merianda TT, Twiss JL, Beattie CE, Steen JA, Sahin M.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10337-42. doi: 10.1073/pnas.1104928108. Epub 2011 Jun 7.

13.

The human insulin mRNA is partly translated via a cap- and eIF4A-independent mechanism.

Fred RG, Sandberg M, Pelletier J, Welsh N.

Biochem Biophys Res Commun. 2011 Sep 9;412(4):693-8. doi: 10.1016/j.bbrc.2011.08.030. Epub 2011 Aug 16.

PMID:
21867683
14.

HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects.

Hubers L, Valderrama-Carvajal H, Laframboise J, Timbers J, Sanchez G, Côté J.

Hum Mol Genet. 2011 Feb 1;20(3):553-79. doi: 10.1093/hmg/ddq500. Epub 2010 Nov 18.

PMID:
21088113
15.

Increased expression of axogenesis-related genes and mossy fibre length in dentate granule cells from adult HuD overexpressor mice.

Perrone-Bizzozero NI, Tanner DC, Mounce J, Bolognani F.

ASN Neuro. 2011;3(5):259-70. doi: 10.1042/AN20110015.

16.

HuD interacts with Bdnf mRNA and is essential for activity-induced BDNF synthesis in dendrites.

Vanevski F, Xu B.

PLoS One. 2015 Feb 18;10(2):e0117264. doi: 10.1371/journal.pone.0117264. eCollection 2015.

17.

A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation.

Wicksteed B, Uchizono Y, Alarcon C, McCuaig JF, Shalev A, Rhodes CJ.

Cell Metab. 2007 Mar;5(3):221-7.

18.

Effects of c-MYC activation on glucose stimulus-secretion coupling events in mouse pancreatic islets.

Pascal SM, Guiot Y, Pelengaris S, Khan M, Jonas JC.

Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E92-102. doi: 10.1152/ajpendo.90235.2008. Epub 2008 Apr 15.

19.

Promotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family members.

Wang H, Molfenter J, Zhu H, Lou H.

Nucleic Acids Res. 2010 Jun;38(11):3760-70. doi: 10.1093/nar/gkq028. Epub 2010 Feb 16.

20.

Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets.

Bolognani F, Contente-Cuomo T, Perrone-Bizzozero NI.

Nucleic Acids Res. 2010 Jan;38(1):117-30. doi: 10.1093/nar/gkp863. Epub 2009 Oct 21.

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