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Items: 1 to 20 of 87

1.

Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation.

Singh AM, Reynolds D, Cliff T, Ohtsuka S, Mattheyses AL, Sun Y, Menendez L, Kulik M, Dalton S.

Cell Stem Cell. 2012 Mar 2;10(3):312-26. doi: 10.1016/j.stem.2012.01.014.

2.

Smad2 is essential for maintenance of the human and mouse primed pluripotent stem cell state.

Sakaki-Yumoto M, Liu J, Ramalho-Santos M, Yoshida N, Derynck R.

J Biol Chem. 2013 Jun 21;288(25):18546-60. doi: 10.1074/jbc.M112.446591. Epub 2013 May 6.

3.

Dissecting signaling pathways that govern self-renewal of rabbit embryonic stem cells.

Wang S, Shen Y, Yuan X, Chen K, Guo X, Chen Y, Niu Y, Li J, Xu RH, Yan X, Zhou Q, Ji W.

J Biol Chem. 2008 Dec 19;283(51):35929-40. doi: 10.1074/jbc.M804091200. Epub 2008 Oct 20.

4.

Reconciling the different roles of Gsk3β in "naïve" and "primed" pluripotent stem cells.

Singh AM, Bechard M, Smith K, Dalton S.

Cell Cycle. 2012 Aug 15;11(16):2991-6. doi: 10.4161/cc.21110. Epub 2012 Jul 24.

5.
6.

Developmentally regulated SMAD2 and SMAD3 utilization directs activin signaling outcomes.

Itman C, Small C, Griswold M, Nagaraja AK, Matzuk MM, Brown CW, Jans DA, Loveland KL.

Dev Dyn. 2009 Jul;238(7):1688-700. doi: 10.1002/dvdy.21995.

7.

The SMAD2/3 corepressor SNON maintains pluripotency through selective repression of mesendodermal genes in human ES cells.

Tsuneyoshi N, Tan EK, Sadasivam A, Poobalan Y, Sumi T, Nakatsuji N, Suemori H, Dunn NR.

Genes Dev. 2012 Nov 15;26(22):2471-6. doi: 10.1101/gad.201772.112.

8.

Activin/nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark.

Bertero A, Madrigal P, Galli A, Hubner NC, Moreno I, Burks D, Brown S, Pedersen RA, Gaffney D, Mendjan S, Pauklin S, Vallier L.

Genes Dev. 2015 Apr 1;29(7):702-17. doi: 10.1101/gad.255984.114. Epub 2015 Mar 24.

9.

Where PI3K/Akt meets Smads: the crosstalk determines human embryonic stem cell fate.

Chen YG, Li Z, Wang XF.

Cell Stem Cell. 2012 Mar 2;10(3):231-2. doi: 10.1016/j.stem.2012.02.008.

10.
11.

Activation of PDK-1 maintains mouse embryonic stem cell self-renewal in a PKB-dependent manner.

Ling LS, Voskas D, Woodgett JR.

Oncogene. 2013 Nov 21;32(47):5397-408. doi: 10.1038/onc.2013.44. Epub 2013 Mar 4.

12.

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells.

James D, Levine AJ, Besser D, Hemmati-Brivanlou A.

Development. 2005 Mar;132(6):1273-82. Epub 2005 Feb 9.

13.

Transcription elongation factor Tcea3 regulates the pluripotent differentiation potential of mouse embryonic stem cells via the Lefty1-Nodal-Smad2 pathway.

Park KS, Cha Y, Kim CH, Ahn HJ, Kim D, Ko S, Kim KH, Chang MY, Ko JH, Noh YS, Han YM, Kim J, Song J, Kim JY, Tesar PJ, Lanza R, Lee KA, Kim KS.

Stem Cells. 2013 Feb;31(2):282-92. doi: 10.1002/stem.1284.

14.

TbetaRI independently activates Smad- and CD2AP-dependent pathways in podocytes.

Xavier S, Niranjan T, Krick S, Zhang T, Ju W, Shaw AS, Schiffer M, Böttinger EP.

J Am Soc Nephrol. 2009 Oct;20(10):2127-37. doi: 10.1681/ASN.2008070806. Epub 2009 Aug 13.

15.

Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification.

Liu L, Liu X, Ren X, Tian Y, Chen Z, Xu X, Du Y, Jiang C, Fang Y, Liu Z, Fan B, Zhang Q, Jin G, Yang X, Zhang X.

Sci Rep. 2016 Feb 24;6:21602. doi: 10.1038/srep21602.

16.

Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development.

Takimoto T, Wakabayashi Y, Sekiya T, Inoue N, Morita R, Ichiyama K, Takahashi R, Asakawa M, Muto G, Mori T, Hasegawa E, Saika S, Hara T, Nomura M, Yoshimura A.

J Immunol. 2010 Jul 15;185(2):842-55. doi: 10.4049/jimmunol.0904100. Epub 2010 Jun 14. Erratum in: J Immunol. 2011 Jan 1;186(1):632. Shizuya, Saika [corrected to Saika, Shizuya].

17.

Role of ALK5/Smad2/3 and MEK1/ERK Signaling in Transforming Growth Factor Beta 1-modulated Growth, Collagen Turnover, and Differentiation of Stem Cells from Apical Papilla of Human Tooth.

Chang HH, Chang MC, Wu IH, Huang GF, Huang WL, Wang YL, Lee SY, Yeh CY, Guo MK, Chan CP, Hsien HC, Jeng JH.

J Endod. 2015 Aug;41(8):1272-80. doi: 10.1016/j.joen.2015.03.022. Epub 2015 May 19.

PMID:
26001858
18.

Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development.

Holtzhausen A, Golzio C, How T, Lee YH, Schiemann WP, Katsanis N, Blobe GC.

FASEB J. 2014 Mar;28(3):1248-67. doi: 10.1096/fj.13-239178. Epub 2013 Dec 5.

19.

Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells.

Greber B, Wu G, Bernemann C, Joo JY, Han DW, Ko K, Tapia N, Sabour D, Sterneckert J, Tesar P, Schöler HR.

Cell Stem Cell. 2010 Mar 5;6(3):215-26. doi: 10.1016/j.stem.2010.01.003.

20.

SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice.

Wu Q, Fukuda K, Weinstein M, Graff JM, Saga Y.

Development. 2015 Feb 1;142(3):575-86. doi: 10.1242/dev.119446.

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