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Items: 1 to 20 of 99

1.

Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus.

Migdall-Wilson J, Bates C, Schlegel J, Brandão L, Linger RM, DeRyckere D, Graham DK.

PLoS One. 2012;7(2):e31635. doi: 10.1371/journal.pone.0031635. Epub 2012 Feb 20.

2.

Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions.

Weinger JG, Omari KM, Marsden K, Raine CS, Shafit-Zagardo B.

Am J Pathol. 2009 Jul;175(1):283-93. doi: 10.2353/ajpath.2009.080807. Epub 2009 Jun 18.

3.
5.

A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells.

Wu Y, Singh S, Georgescu MM, Birge RB.

J Cell Sci. 2005 Feb 1;118(Pt 3):539-53.

6.

GAS6/Mer axis regulates the homing and survival of the E2A/PBX1-positive B-cell precursor acute lymphoblastic leukemia in the bone marrow niche.

Shiozawa Y, Pedersen EA, Taichman RS.

Exp Hematol. 2010 Feb;38(2):132-40. doi: 10.1016/j.exphem.2009.11.002. Epub 2009 Nov 14.

7.

Role of Growth arrest-specific gene 6-Mer axis in multiple myeloma.

Waizenegger JS, Ben-Batalla I, Weinhold N, Meissner T, Wroblewski M, Janning M, Riecken K, Binder M, Atanackovic D, Taipaleenmaeki H, Schewe D, Sawall S, Gensch V, Cubas-Cordova M, Seckinger A, Fiedler W, Hesse E, Kröger N, Fehse B, Hose D, Klein B, Raab MS, Pantel K, Bokemeyer C, Loges S.

Leukemia. 2015 Mar;29(3):696-704. doi: 10.1038/leu.2014.236. Epub 2014 Aug 8.

PMID:
25102945
8.

The Mer receptor tyrosine kinase is expressed on discrete macrophage subpopulations and mainly uses Gas6 as its ligand for uptake of apoptotic cells.

Shao WH, Zhen Y, Eisenberg RA, Cohen PL.

Clin Immunol. 2009 Oct;133(1):138-44. doi: 10.1016/j.clim.2009.06.002. Epub 2009 Jul 24.

9.

Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases.

Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, Mizuno K.

J Biol Chem. 1996 Nov 22;271(47):30022-7.

10.

[Advance of study on Mer function].

Fan L, Ruan CG.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007 Aug;15(4):892-5. Review. Chinese.

PMID:
17708828
11.

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma.

Ben-Batalla I, Schultze A, Wroblewski M, Erdmann R, Heuser M, Waizenegger JS, Riecken K, Binder M, Schewe D, Sawall S, Witzke V, Cubas-Cordova M, Janning M, Wellbrock J, Fehse B, Hagel C, Krauter J, Ganser A, Lorens JB, Fiedler W, Carmeliet P, Pantel K, Bokemeyer C, Loges S.

Blood. 2013 Oct 3;122(14):2443-52. doi: 10.1182/blood-2013-03-491431. Epub 2013 Aug 27.

13.

Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.

Lew ED, Oh J, Burrola PG, Lax I, Zagórska A, Través PG, Schlessinger J, Lemke G.

Elife. 2014 Sep 29;3. doi: 10.7554/eLife.03385.

14.
15.

A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation.

Sather S, Kenyon KD, Lefkowitz JB, Liang X, Varnum BC, Henson PM, Graham DK.

Blood. 2007 Feb 1;109(3):1026-33. Epub 2006 Oct 17.

16.

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

Mishra A, Wang J, Shiozawa Y, McGee S, Kim J, Jung Y, Joseph J, Berry JE, Havens A, Pienta KJ, Taichman RS.

Mol Cancer Res. 2012 Jun;10(6):703-12. doi: 10.1158/1541-7786.MCR-11-0569. Epub 2012 Apr 19.

17.

Mer signaling increases the abundance of the transcription factor LXR to promote the resolution of acute sterile inflammation.

Choi JY, Seo JY, Yoon YS, Lee YJ, Kim HS, Kang JL.

Sci Signal. 2015 Feb 24;8(365):ra21. doi: 10.1126/scisignal.2005864.

PMID:
25714463
18.

Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.

Tsou WI, Nguyen KQ, Calarese DA, Garforth SJ, Antes AL, Smirnov SV, Almo SC, Birge RB, Kotenko SV.

J Biol Chem. 2014 Sep 12;289(37):25750-63. doi: 10.1074/jbc.M114.569020. Epub 2014 Jul 29.

19.
20.

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia.

Lee-Sherick AB, Eisenman KM, Sather S, McGranahan A, Armistead PM, McGary CS, Hunsucker SA, Schlegel J, Martinson H, Cannon C, Keating AK, Earp HS, Liang X, DeRyckere D, Graham DK.

Oncogene. 2013 Nov 14;32(46):5359-68. doi: 10.1038/onc.2013.40. Epub 2013 Mar 11.

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