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Items: 1 to 20 of 102

1.

Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.

Clarke R, Bennett DA, Parish S, Verhoef P, Dötsch-Klerk M, Lathrop M, Xu P, Nordestgaard BG, Holm H, Hopewell JC, Saleheen D, Tanaka T, Anand SS, Chambers JC, Kleber ME, Ouwehand WH, Yamada Y, Elbers C, Peters B, Stewart AF, Reilly MM, Thorand B, Yusuf S, Engert JC, Assimes TL, Kooner J, Danesh J, Watkins H, Samani NJ, Collins R, Peto R; MTHFR Studies Collaborative Group.

PLoS Med. 2012 Feb;9(2):e1001177. doi: 10.1371/journal.pmed.1001177. Epub 2012 Feb 21.

2.

MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

Klerk M, Verhoef P, Clarke R, Blom HJ, Kok FJ, Schouten EG; MTHFR Studies Collaboration Group.

JAMA. 2002 Oct 23-30;288(16):2023-31.

PMID:
12387655
3.

Association between C677T polymorphism of methylene tetrahydrofolate reductase and congenital heart disease: meta-analysis of 7697 cases and 13,125 controls.

Mamasoula C, Prentice RR, Pierscionek T, Pangilinan F, Mills JL, Druschel C, Pass K, Russell MW, Hall D, Töpf A, Brown DL, Zelenika D, Bentham J, Cosgrove C, Bhattacharya S, Riveron JG, Setchfield K, Brook JD, Bu'Lock FA, Thornborough C, Rahman TJ, Doza JP, Tan HL, O'Sullivan J, Stuart AG, Blue G, Winlaw D, Postma AV, Mulder BJ, Zwinderman AH, van Engelen K, Moorman AF, Rauch A, Gewillig M, Breckpot J, Devriendt K, Lathrop GM, Farrall M, Goodship JA, Cordell HJ, Brody LC, Keavney BD.

Circ Cardiovasc Genet. 2013 Aug;6(4):347-53. doi: 10.1161/CIRCGENETICS.113.000191. Epub 2013 Jul 22.

4.
5.

The association between plasma homocysteine and coronary heart disease is modified by the MTHFR 677C>T polymorphism.

Mehlig K, Leander K, de Faire U, Nyberg F, Berg C, Rosengren A, Björck L, Zetterberg H, Blennow K, Tognon G, Torén K, Strandhagen E, Lissner L, Thelle D.

Heart. 2013 Dec;99(23):1761-5. doi: 10.1136/heartjnl-2013-304460. Epub 2013 Sep 7.

PMID:
24014284
6.

The C677T mutation in methylenetetrahydrofolate reductase gene, plasma homocysteine concentration and the risk of coronary artery disease.

Kadziela J, Janas J, Dzielińska Z, Szperl M, Gaździk D, Chotkowska E, Piotrowski W, Ruzyłło W.

Kardiol Pol. 2003 Jul;59(7):17-26; discussion 26.

PMID:
14560345
7.

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials.

Holmes MV, Newcombe P, Hubacek JA, Sofat R, Ricketts SL, Cooper J, Breteler MM, Bautista LE, Sharma P, Whittaker JC, Smeeth L, Fowkes FG, Algra A, Shmeleva V, Szolnoki Z, Roest M, Linnebank M, Zacho J, Nalls MA, Singleton AB, Ferrucci L, Hardy J, Worrall BB, Rich SS, Matarin M, Norman PE, Flicker L, Almeida OP, van Bockxmeer FM, Shimokata H, Khaw KT, Wareham NJ, Bobak M, Sterne JA, Smith GD, Talmud PJ, van Duijn C, Humphries SE, Price JF, Ebrahim S, Lawlor DA, Hankey GJ, Meschia JF, Sandhu MS, Hingorani AD, Casas JP.

Lancet. 2011 Aug 13;378(9791):584-94. doi: 10.1016/S0140-6736(11)60872-6. Epub 2011 Jul 29.

8.
9.

Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms, plasma homocysteine, folate, and vitamin B12 levels and the extent of coronary artery disease.

Kölling K, Ndrepepa G, Koch W, Braun S, Mehilli J, Schömig A, Kastrati A.

Am J Cardiol. 2004 May 15;93(10):1201-6.

PMID:
15135689
11.

Methylenetetrahydrofolate reductase 677 C-->T mutation and coronary heart disease risk in UK Indian Asians.

Chambers JC, Ireland H, Thompson E, Reilly P, Obeid OA, Refsum H, Ueland P, Lane DA, Kooner JS.

Arterioscler Thromb Vasc Biol. 2000 Nov;20(11):2448-52.

12.

The impact of MTHFR 677 C/T genotypes on folate status markers: a meta-analysis of folic acid intervention studies.

Colson NJ, Naug HL, Nikbakht E, Zhang P, McCormack J.

Eur J Nutr. 2017 Feb;56(1):247-260. doi: 10.1007/s00394-015-1076-x. Epub 2015 Oct 23.

PMID:
26497154
13.

Methylenetetrahydrofolate reductase (MTHFR) c677t gene variant modulates the homocysteine folate correlation in a mild folate-deficient population.

Pereira AC, Schettert IT, Morandini Filho AA, Guerra-Shinohara EM, Krieger JE.

Clin Chim Acta. 2004 Feb;340(1-2):99-105.

PMID:
14734201
14.

5,10-Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms: genotype frequency and association with homocysteine and folate levels in middle-southern Italian adults.

Zappacosta B, Graziano M, Persichilli S, Di Castelnuovo A, Mastroiacovo P, Iacoviello L.

Cell Biochem Funct. 2014 Jan;32(1):1-4. doi: 10.1002/cbf.3019. Epub 2013 Nov 26.

PMID:
24277487
15.

MTHFR C677T and A1298C gene polymorphisms and their relation to homocysteine level in Egyptian children with congenital heart diseases.

Zidan HE, Rezk NA, Mohammed D.

Gene. 2013 Oct 15;529(1):119-24. doi: 10.1016/j.gene.2013.07.053. Epub 2013 Aug 8.

PMID:
23933414
16.

Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults.

Yang Q, Bailey L, Clarke R, Flanders WD, Liu T, Yesupriya A, Khoury MJ, Friedman JM.

Am J Clin Nutr. 2012 May;95(5):1245-53. doi: 10.3945/ajcn.111.022384. Epub 2012 Apr 4.

17.

Methylene tetrahydrofolate reductase genotype and the risk and extent of coronary artery disease in a population with low plasma folate.

Tokgözoğlu SL, Alikaşifoğlu M, Unsal, Atalar E, Aytemir K, Ozer N, Ovünç K, Usal O, Kes S, Tunçbilek E.

Heart. 1999 May;81(5):518-22.

18.

Effect of MTHFR 677C>T on plasma total homocysteine levels in renal graft recipients.

Födinger M, Wölfl G, Fischer G, Rasoul-Rockenschaub S, Schmid R, Hörl WH, Sunder-Plassmann G.

Kidney Int. 1999 Mar;55(3):1072-80.

19.

MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification.

Husemoen LL, Skaaby T, Jørgensen T, Thuesen BH, Fenger M, Grarup N, Sandholt CH, Hansen T, Pedersen O, Linneberg A.

Eur J Nutr. 2014 Oct;53(7):1549-59. doi: 10.1007/s00394-014-0659-2. Epub 2014 Jan 24.

PMID:
24458267
20.

Three genetic polymorphisms of homocysteine-metabolizing enzymes and risk of coronary heart disease: a meta-analysis based on 23 case-control studies.

Chen L, Liu L, Hong K, Hu J, Cheng X.

DNA Cell Biol. 2012 Feb;31(2):238-49. doi: 10.1089/dna.2011.1281. Epub 2011 Jul 22.

PMID:
21780915

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