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Items: 1 to 20 of 124

1.

Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout.

Swift F, Franzini-Armstrong C, Øyehaug L, Enger UH, Andersson KB, Christensen G, Sejersted OM, Louch WE.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3997-4001. doi: 10.1073/pnas.1120172109. Epub 2012 Feb 21.

2.

Calcium dynamics in the ventricular myocytes of SERCA2 knockout mice: A modeling study.

Li L, Louch WE, Niederer SA, Andersson KB, Christensen G, Sejersted OM, Smith NP.

Biophys J. 2011 Jan 19;100(2):322-31. doi: 10.1016/j.bpj.2010.11.048.

3.

Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout.

Louch WE, Hougen K, Mørk HK, Swift F, Aronsen JM, Sjaastad I, Reims HM, Roald B, Andersson KB, Christensen G, Sejersted OM.

J Physiol. 2010 Feb 1;588(Pt 3):465-78. doi: 10.1113/jphysiol.2009.183517. Epub 2009 Dec 14.

4.

Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity.

Øyehaug L, Loose KØ, Jølle GF, Røe ÅT, Sjaastad I, Christensen G, Sejersted OM, Louch WE.

Biophys J. 2013 Apr 16;104(8):1685-97. doi: 10.1016/j.bpj.2013.03.022.

5.

Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes.

Stokke MK, Hougen K, Sjaastad I, Louch WE, Briston SJ, Enger UH, Andersson KB, Christensen G, Eisner DA, Sejersted OM, Trafford AW.

Cardiovasc Res. 2010 Apr 1;86(1):63-71. doi: 10.1093/cvr/cvp401. Epub 2009 Dec 17.

6.

Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene.

Andersson KB, Birkeland JA, Finsen AV, Louch WE, Sjaastad I, Wang Y, Chen J, Molkentin JD, Chien KR, Sejersted OM, Christensen G.

J Mol Cell Cardiol. 2009 Aug;47(2):180-7. doi: 10.1016/j.yjmcc.2009.03.013. Epub 2009 Mar 26.

PMID:
19328205
7.

Depletion of T-tubules and specific subcellular changes in sarcolemmal proteins in tachycardia-induced heart failure.

Balijepalli RC, Lokuta AJ, Maertz NA, Buck JM, Haworth RA, Valdivia HH, Kamp TJ.

Cardiovasc Res. 2003 Jul 1;59(1):67-77.

8.

Sarcoplasmic reticulum Ca(2+) atpase (SERCA) 1a structurally substitutes for SERCA2a in the cardiac sarcoplasmic reticulum and increases cardiac Ca(2+) handling capacity.

Lalli MJ, Yong J, Prasad V, Hashimoto K, Plank D, Babu GJ, Kirkpatrick D, Walsh RA, Sussman M, Yatani A, Marbán E, Periasamy M.

Circ Res. 2001 Jul 20;89(2):160-7.

9.

Cardiomyocyte-specific disruption of Serca2 in adult mice causes sarco(endo)plasmic reticulum stress and apoptosis.

Liu XH, Zhang ZY, Andersson KB, Husberg C, Enger UH, Ræder MG, Christensen G, Louch WE.

Cell Calcium. 2011 Apr;49(4):201-7. doi: 10.1016/j.ceca.2010.09.009. Epub 2010 Oct 20.

PMID:
20965565
10.

Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content.

Stokke MK, Briston SJ, Jølle GF, Manzoor I, Louch WE, Øyehaug L, Christensen G, Eisner DA, Trafford AW, Sejersted OM, Sjaastad I.

Cardiovasc Res. 2011 Jun 1;90(3):503-12. doi: 10.1093/cvr/cvr013. Epub 2011 Jan 17.

11.

Modulation of SR Ca2+ release by the triadin-to-calsequestrin ratio in ventricular myocytes.

Kučerová D, Baba HA, Bokník P, Fabritz L, Heinick A, Mát'uš M, Müller FU, Neumann J, Schmitz W, Kirchhefer U.

Am J Physiol Heart Circ Physiol. 2012 May 15;302(10):H2008-17. doi: 10.1152/ajpheart.00457.2011. Epub 2012 Mar 16.

12.

Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice.

Yan W, Zhang F, Zhang R, Zhang X, Wang Y, Zhou F, Xia Y, Liu P, Gao C, Wang H, Zhang L, Zhou J, Gao F, Gao E, Koch WJ, Wang H, Cheng H, Qu Y, Tao L.

J Mol Cell Cardiol. 2014 Sep;74:183-92. doi: 10.1016/j.yjmcc.2014.05.010. Epub 2014 May 20.

PMID:
24852843
13.

Intermittent hypoxia protects cardiomyocytes against ischemia-reperfusion injury-induced alterations in Ca2+ homeostasis and contraction via the sarcoplasmic reticulum and Na+/Ca2+ exchange mechanisms.

Chen L, Lu XY, Li J, Fu JD, Zhou ZN, Yang HT.

Am J Physiol Cell Physiol. 2006 Apr;290(4):C1221-9. Epub 2005 Nov 23. Erratum in: Am J Physiol Cell Physiol. 2006 Nov;291(5):C1099.

14.

Massive alterations of sarcoplasmic reticulum free calcium in skeletal muscle fibers lacking calsequestrin revealed by a genetically encoded probe.

Canato M, Scorzeto M, Giacomello M, Protasi F, Reggiani C, Stienen GJ.

Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22326-31. doi: 10.1073/pnas.1009168108. Epub 2010 Dec 6.

15.

Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release.

Maier LS, Zhang T, Chen L, DeSantiago J, Brown JH, Bers DM.

Circ Res. 2003 May 2;92(8):904-11. Epub 2003 Apr 3.

16.

Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1.

Paolini C, Quarta M, Nori A, Boncompagni S, Canato M, Volpe P, Allen PD, Reggiani C, Protasi F.

J Physiol. 2007 Sep 1;583(Pt 2):767-84. Epub 2007 Jul 12.

17.

Sarcoplasmic reticulum Ca2+ refilling controls recovery from Ca2+-induced Ca2+ release refractoriness in heart muscle.

Szentesi P, Pignier C, Egger M, Kranias EG, Niggli E.

Circ Res. 2004 Oct 15;95(8):807-13. Epub 2004 Sep 23.

18.

Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle.

Sjåland C, Lunde PK, Swift F, Munkvik M, Ericsson M, Lunde M, Boye S, Christensen G, Ellingsen Ø, Sejersted OM, Andersson KB.

J Physiol. 2011 Dec 15;589(Pt 24):6139-55. doi: 10.1113/jphysiol.2011.211987. Epub 2011 Sep 26.

20.

T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction.

Louch WE, Mørk HK, Sexton J, Strømme TA, Laake P, Sjaastad I, Sejersted OM.

J Physiol. 2006 Jul 15;574(Pt 2):519-33. Epub 2006 May 18.

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