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Items: 1 to 20 of 181

1.

The impact of network biology in pharmacology and toxicology.

Panagiotou G, Taboureau O.

SAR QSAR Environ Res. 2012;23(3-4):221-35. doi: 10.1080/1062936X.2012.657237. Epub 2012 Feb 22. Review.

PMID:
22352466
2.

The effect of network biology on drug toxicology.

Gautier L, Taboureau O, Audouze K.

Expert Opin Drug Metab Toxicol. 2013 Nov;9(11):1409-18. doi: 10.1517/17425255.2013.820704. Epub 2013 Aug 12. Review.

PMID:
23937336
3.

Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies.

Aardema MJ, MacGregor JT.

Mutat Res. 2002 Jan 29;499(1):13-25. Review.

PMID:
11804602
4.

[Network pharmacology and drug discovery].

Wang J, Li XJ.

Sheng Li Ke Xue Jin Zhan. 2011 Aug;42(4):241-5. Review. Chinese.

PMID:
22066413
5.

Unveiling the role of network and systems biology in drug discovery.

Pujol A, Mosca R, Farrés J, Aloy P.

Trends Pharmacol Sci. 2010 Mar;31(3):115-23. doi: 10.1016/j.tips.2009.11.006. Epub 2010 Feb 1. Review.

PMID:
20117850
6.

Network analyses in systems pharmacology.

Berger SI, Iyengar R.

Bioinformatics. 2009 Oct 1;25(19):2466-72. doi: 10.1093/bioinformatics/btp465. Epub 2009 Jul 30. Review.

7.

Network systems biology for drug discovery.

Arrell DK, Terzic A.

Clin Pharmacol Ther. 2010 Jul;88(1):120-5. doi: 10.1038/clpt.2010.91. Epub 2010 Jun 2. Review.

PMID:
20520604
8.

Proteomics and systems biology: application in drug discovery and development.

Chakravarti B, Mallik B, Chakravarti DN.

Methods Mol Biol. 2010;662:3-28. doi: 10.1007/978-1-60761-800-3_1. Review.

PMID:
20824464
9.

Informed toxicity assessment in drug discovery: systems-based toxicology.

Mayne JT, Ku WW, Kennedy SP.

Curr Opin Drug Discov Devel. 2006 Jan;9(1):75-83. Review.

PMID:
16445119
10.

Drug discovery in the age of systems biology: the rise of computational approaches for data integration.

Iskar M, Zeller G, Zhao XM, van Noort V, Bork P.

Curr Opin Biotechnol. 2012 Aug;23(4):609-16. doi: 10.1016/j.copbio.2011.11.010. Epub 2011 Dec 5. Review.

PMID:
22153034
11.

Adopting network pharmacology for cancer drug discovery.

Azmi AS.

Curr Drug Discov Technol. 2013 Jun;10(2):95-105. Review.

PMID:
23237672
12.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
13.

Systems biology impact on antiepileptic drug discovery.

Margineanu DG.

Epilepsy Res. 2012 Feb;98(2-3):104-15. doi: 10.1016/j.eplepsyres.2011.10.006. Epub 2011 Nov 3. Review.

PMID:
22055355
14.

Molecular clinical safety intelligence: a system for bridging clinically focused safety knowledge to early-stage drug discovery - the GSK experience.

Vanderwall DE, Yuen N, Al-Ansari M, Bailey J, Fram D, Green DV, Pickett S, Vitulli G, Luengo JI, Almenoff JS.

Drug Discov Today. 2011 Aug;16(15-16):646-53. doi: 10.1016/j.drudis.2011.05.001. Epub 2011 May 11.

PMID:
21601652
15.

Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases.

Li P, Chen J, Wang J, Zhou W, Wang X, Li B, Tao W, Wang W, Wang Y, Yang L.

J Ethnopharmacol. 2014;151(1):93-107. doi: 10.1016/j.jep.2013.07.001. Epub 2013 Jul 9.

PMID:
23850710
16.

Using quantitative systems pharmacology for novel drug discovery.

Pérez-Nueno VI.

Expert Opin Drug Discov. 2015 Dec;10(12):1315-31. doi: 10.1517/17460441.2015.1082543. Epub 2015 Aug 25. Review.

PMID:
26328768
17.

Systems pharmacology to predict drug toxicity: integration across levels of biological organization.

Bai JP, Abernethy DR.

Annu Rev Pharmacol Toxicol. 2013;53:451-73. doi: 10.1146/annurev-pharmtox-011112-140248. Epub 2012 Nov 5. Review.

PMID:
23140241
18.

Applying systems biology in drug discovery and development.

Galizzi JP, Lockhart BP, Bril A.

Drug Metabol Drug Interact. 2013;28(2):67-78. doi: 10.1515/dmdi-2013-0002. Review.

PMID:
23612649
19.

Systems pharmacology: network analysis to identify multiscale mechanisms of drug action.

Zhao S, Iyengar R.

Annu Rev Pharmacol Toxicol. 2012;52:505-21. doi: 10.1146/annurev-pharmtox-010611-134520. Review.

20.

The feasibility of replacing animal testing for assessing consumer safety: a suggested future direction.

Fentem J, Chamberlain M, Sangster B.

Altern Lab Anim. 2004 Dec;32(6):617-23.

PMID:
15757499

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