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Items: 1 to 20 of 103

1.

mtDNA lineage analysis of mouse L-cell lines reveals the accumulation of multiple mtDNA mutants and intermolecular recombination.

Fan W, Lin CS, Potluri P, Procaccio V, Wallace DC.

Genes Dev. 2012 Feb 15;26(4):384-94. doi: 10.1101/gad.175802.111.

2.

Part II. Mitochondrial mutational status of high nitric oxide adapted cell line BT-20 (BT-20-HNO) as it relates to human primary breast tumors.

De Vitto H, Mendonça BS, Elseth KM, Vesper BJ, Portari EA, Gallo CV, Paradise WA, Rumjanek FD, Radosevich JA.

Tumour Biol. 2013 Feb;34(1):337-47. doi: 10.1007/s13277-012-0555-4. Epub 2012 Dec 14.

PMID:
23238816
3.

mtDNA mutations increase tumorigenicity in prostate cancer.

Petros JA, Baumann AK, Ruiz-Pesini E, Amin MB, Sun CQ, Hall J, Lim S, Issa MM, Flanders WD, Hosseini SH, Marshall FF, Wallace DC.

Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):719-24. Epub 2005 Jan 12.

4.

A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis.

Park JS, Sharma LK, Li H, Xiang R, Holstein D, Wu J, Lechleiter J, Naylor SL, Deng JJ, Lu J, Bai Y.

Hum Mol Genet. 2009 May 1;18(9):1578-89. doi: 10.1093/hmg/ddp069. Epub 2009 Feb 10.

5.

Cancer cell mitochondria confer apoptosis resistance and promote metastasis.

Kulawiec M, Owens KM, Singh KK.

Cancer Biol Ther. 2009 Jul;8(14):1378-85. Epub 2009 Jul 16.

PMID:
19556849
6.

Enhanced tumorigenicity by mitochondrial DNA mild mutations.

Cruz-Bermúdez A, Vallejo CG, Vicente-Blanco RJ, Gallardo ME, Fernández-Moreno MÁ, Quintanilla M, Garesse R.

Oncotarget. 2015 May 30;6(15):13628-43.

7.

Origin, transmission, and segregation of mitochondrial DNA dimers in mouse hybrid and cybrid cell lines.

Howell N, Huang P, Kolodner RD.

Somat Cell Mol Genet. 1984 May;10(3):259-74.

PMID:
6585971
8.

Clinical, genetic, and biochemical characterization of a Leber hereditary optic neuropathy family containing both the 11778 and 14484 primary mutations.

Brown MD, Allen JC, Van Stavern GP, Newman NJ, Wallace DC.

Am J Med Genet. 2001 Dec 15;104(4):331-8.

PMID:
11754070
9.

Cybrid models of mtDNA disease and transmission, from cells to mice.

Trounce IA, Pinkert CA.

Curr Top Dev Biol. 2007;77:157-83. Review.

PMID:
17222703
10.

MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases.

Hashimoto M, Bacman SR, Peralta S, Falk MJ, Chomyn A, Chan DC, Williams SL, Moraes CT.

Mol Ther. 2015 Oct;23(10):1592-9. doi: 10.1038/mt.2015.126. Epub 2015 Jul 10.

11.

Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells.

Kasahara A, Ishikawa K, Yamaoka M, Ito M, Watanabe N, Akimoto M, Sato A, Nakada K, Endo H, Suda Y, Aizawa S, Hayashi J.

Hum Mol Genet. 2006 Mar 15;15(6):871-81. Epub 2006 Jan 31.

PMID:
16449238
12.

The generation of oxidative stress-induced rearrangements in Saccharomyces cerevisiae mtDNA is dependent on the Nuc1 (EndoG/ExoG) nuclease and is enhanced by inactivation of the MRX complex.

Dzierzbicki P, Kaniak-Golik A, Malc E, Mieczkowski P, Ciesla Z.

Mutat Res. 2012 Dec;740(1-2):21-33. doi: 10.1016/j.mrfmmm.2012.12.004. Epub 2012 Dec 28.

PMID:
23276591
13.

Mitochondrial disease in mouse results in increased oxidative stress.

Esposito LA, Melov S, Panov A, Cottrell BA, Wallace DC.

Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):4820-5.

14.

Analysis of European mtDNAs for recombination.

Elson JL, Andrews RM, Chinnery PF, Lightowlers RN, Turnbull DM, Howell N.

Am J Hum Genet. 2001 Jan;68(1):145-153. Epub 2000 Dec 11.

15.

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming.

Picard M, Zhang J, Hancock S, Derbeneva O, Golhar R, Golik P, O'Hearn S, Levy S, Potluri P, Lvova M, Davila A, Lin CS, Perin JC, Rappaport EF, Hakonarson H, Trounce IA, Procaccio V, Wallace DC.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):E4033-42. doi: 10.1073/pnas.1414028111. Epub 2014 Sep 5.

16.

Mitochondrial mutations in cancer.

Brandon M, Baldi P, Wallace DC.

Oncogene. 2006 Aug 7;25(34):4647-62. Review.

PMID:
16892079
17.

Animal models for mitochondrial disease.

Wallace DC.

Methods Mol Biol. 2002;197:3-54. Review.

PMID:
12013805
18.

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production.

Trifunovic A, Hansson A, Wredenberg A, Rovio AT, Dufour E, Khvorostov I, Spelbrink JN, Wibom R, Jacobs HT, Larsson NG.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):17993-8. Epub 2005 Dec 6.

19.

Determination of normal ranges of mitochondrial respiratory activities by mtDNA transfer from 54 Human subjects to mtDNA-less HeLa cells for identification of the pathogenicities of mutated mtDNAs.

Chen CS, Matsuoka R, Arai S, Momiyama Y, Murakami H, Kuno SY, Ishikawa K, Nakada K, Tawata M, Hayashi J.

J Biochem. 2004 Feb;135(2):237-43.

20.

Mitochondrial theory of aging matures--roles of mtDNA mutation and oxidative stress in human aging.

Wei YH, Ma YS, Lee HC, Lee CF, Lu CY.

Zhonghua Yi Xue Za Zhi (Taipei). 2001 May;64(5):259-70. Review.

PMID:
11499335

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