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Items: 1 to 20 of 116

1.

Management of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone-induced methemoglobinemia.

Kunos CA, Radivoyevitch T, Ingalls ST, Hoppel CL.

Future Oncol. 2012 Feb;8(2):145-50. doi: 10.2217/fon.11.147. Review.

2.

Inhibitors of ribonucleotide reductase. Comparative effects of amino- and hydroxy-substituted pyridine-2-carboxaldehyde thiosemicarbazones.

Cory JG, Cory AH, Rappa G, Lorico A, Liu MC, Lin TS, Sartorelli AC.

Biochem Pharmacol. 1994 Jul 19;48(2):335-44.

PMID:
8053929
3.

A phase I trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone in combination with gemcitabine for patients with advanced cancer.

Yen Y, Margolin K, Doroshow J, Fishman M, Johnson B, Clairmont C, Sullivan D, Sznol M.

Cancer Chemother Pharmacol. 2004 Oct;54(4):331-42. Epub 2004 May 18.

PMID:
15148626
4.
5.

Phase I trial of pelvic radiation, weekly cisplatin, and 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) for locally advanced cervical cancer.

Kunos CA, Waggoner S, von Gruenigen V, Eldermire E, Pink J, Dowlati A, Kinsella TJ.

Clin Cancer Res. 2010 Feb 15;16(4):1298-306. doi: 10.1158/1078-0432.CCR-09-2469. Epub 2010 Feb 9.

6.

Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.

Finch RA, Liu M, Grill SP, Rose WC, Loomis R, Vasquez KM, Cheng Y, Sartorelli AC.

Biochem Pharmacol. 2000 Apr 15;59(8):983-91.

PMID:
10692563
8.

Methemoglobinemia in the differential diagnosis of cyanosis.

Jaffé ER.

Hosp Pract (Off Ed). 1985 Dec 15;20(12):92-6, 101-3, 108-10. No abstract available.

PMID:
3934202
9.

Why does methylene blue reduce methemoglobin in benzocaine poisoning but beneficially oxidize hemoglobin in cyanide poisoning?

Alston TA.

J Clin Anesth. 2014 Dec;26(8):702-3. doi: 10.1016/j.jclinane.2014.09.001. Epub 2014 Oct 27. No abstract available.

PMID:
25441551
10.

Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study.

Popović-Bijelić A, Kowol CR, Lind ME, Luo J, Himo F, Enyedy EA, Arion VB, Gräslund A.

J Inorg Biochem. 2011 Nov;105(11):1422-31. doi: 10.1016/j.jinorgbio.2011.07.003. Epub 2011 Jul 31.

12.

Inhibitory mechanisms of heterocyclic carboxaldehyde thiosemicabazones for two forms of human ribonucleotide reductase.

Zhu L, Zhou B, Chen X, Jiang H, Shao J, Yen Y.

Biochem Pharmacol. 2009 Nov 1;78(9):1178-85. doi: 10.1016/j.bcp.2009.06.103. Epub 2009 Jul 2.

PMID:
19576866
13.

Methemoglobinemia.

Mansouri A.

Am J Med Sci. 1985 May;289(5):200-9.

PMID:
4003427
14.

Phase I study of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehyde-thiosemicarbazone (3-AP) in combination with high dose cytarabine in patients with advanced myeloid leukemia.

Odenike OM, Larson RA, Gajria D, Dolan ME, Delaney SM, Karrison TG, Ratain MJ, Stock W.

Invest New Drugs. 2008 Jun;26(3):233-9. doi: 10.1007/s10637-008-9115-6. Epub 2008 Jan 24.

15.

Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity.

Finch RA, Liu MC, Cory AH, Cory JG, Sartorelli AC.

Adv Enzyme Regul. 1999;39:3-12. Review.

PMID:
10470363
16.

Acquired methemoglobinemia revisited.

Trapp L, Will J.

Dent Clin North Am. 2010 Oct;54(4):665-75. doi: 10.1016/j.cden.2010.06.007. Epub 2010 Aug 7. Review.

PMID:
20831930
17.

Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.

Kowol CR, Trondl R, Heffeter P, Arion VB, Jakupec MA, Roller A, Galanski M, Berger W, Keppler BK.

J Med Chem. 2009 Aug 27;52(16):5032-43. doi: 10.1021/jm900528d.

PMID:
19637923
18.

Methemoglobinemia and local anesthesia: what every dentist should know.

Tentindo G, Rosenberg M.

J Mass Dent Soc. 2010 Summer;59(2):18-20. No abstract available.

PMID:
20806700
19.

Protracted methemoglobinemia after phenazopyridine overdose in an infant.

Christensen CM, Farrar HC, Kearns GL.

J Clin Pharmacol. 1996 Feb;36(2):112-6. Review.

PMID:
8852386
20.

Hospitals should keep methylene blue.

Hernandez EM, Rella J, Ruck B, Marcus S.

Am J Health Syst Pharm. 2004 Apr 15;61(8):842. No abstract available.

PMID:
15127966

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