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Items: 1 to 20 of 83

1.

Human kinome profiling identifies a requirement for AMP-activated protein kinase during human cytomegalovirus infection.

Terry LJ, Vastag L, Rabinowitz JD, Shenk T.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3071-6. doi: 10.1073/pnas.1200494109. Epub 2012 Feb 6.

2.

Profiling of the kinome of cytomegalovirus-infected cells reveals the functional importance of host kinases Aurora A, ABL and AMPK.

Hutterer C, Wandinger SK, Wagner S, Müller R, Stamminger T, Zeitträger I, Godl K, Baumgartner R, Strobl S, Marschall M.

Antiviral Res. 2013 Aug;99(2):139-48. doi: 10.1016/j.antiviral.2013.04.017. Epub 2013 May 4.

PMID:
23648710
3.

Digitoxin Suppresses Human Cytomegalovirus Replication via Na+, K+/ATPase α1 Subunit-Dependent AMP-Activated Protein Kinase and Autophagy Activation.

Mukhopadhyay R, Venkatadri R, Katsnelson J, Arav-Boger R.

J Virol. 2018 Feb 26;92(6). pii: e01861-17. doi: 10.1128/JVI.01861-17. Print 2018 Mar 15.

4.

Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals.

Arend KC, Lenarcic EM, Vincent HA, Rashid N, Lazear E, McDonald IM, Gilbert TS, East MP, Herring LE, Johnson GL, Graves LM, Moorman NJ.

Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S263-S276. doi: 10.1074/mcp.M116.065375. Epub 2017 Feb 25.

5.

HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication.

McArdle J, Moorman NJ, Munger J.

PLoS Pathog. 2012 Jan;8(1):e1002502. doi: 10.1371/journal.ppat.1002502. Epub 2012 Jan 26.

6.

Hydrogen Peroxide Induce Human Cytomegalovirus Replication through the Activation of p38-MAPK Signaling Pathway.

Xiao J, Deng J, Lv L, Kang Q, Ma P, Yan F, Song X, Gao B, Zhang Y, Xu J.

Viruses. 2015 Jun 4;7(6):2816-33. doi: 10.3390/v7062748.

7.

Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data.

Strang BL, Asquith CRM, Moshrif HF, Ho CM, Zuercher WJ, Al-Ali H.

PLoS One. 2018 Jul 26;13(7):e0201321. doi: 10.1371/journal.pone.0201321. eCollection 2018.

8.

High-throughput screening of a GlaxoSmithKline protein kinase inhibitor set identifies an inhibitor of human cytomegalovirus replication that prevents CREB and histone H3 post-translational modification.

Khan AS, Murray MJ, Ho CMK, Zuercher WJ, Reeves MB, Strang BL.

J Gen Virol. 2017 Apr;98(4):754-768. doi: 10.1099/jgv.0.000713. Epub 2017 Apr 20.

10.

AMPK-mediated inhibition of mTOR kinase is circumvented during immediate-early times of human cytomegalovirus infection.

Kudchodkar SB, Del Prete GQ, Maguire TG, Alwine JC.

J Virol. 2007 Apr;81(7):3649-51. Epub 2007 Jan 10.

11.

Differentiation-Coupled Induction of Human Cytomegalovirus Replication by Union of the Major Enhancer Retinoic Acid, Cyclic AMP, and NF-κB Response Elements.

Yuan J, Li M, Torres YR, Galle CS, Meier JL.

J Virol. 2015 Dec;89(24):12284-98. doi: 10.1128/JVI.00965-15. Epub 2015 Sep 30.

12.

Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication.

Moorman NJ, Shenk T.

J Virol. 2010 May;84(10):5260-9. doi: 10.1128/JVI.02733-09. Epub 2010 Feb 24.

13.

Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells.

Yuan J, Liu X, Wu AW, McGonagill PW, Keller MJ, Galle CS, Meier JL.

J Virol. 2009 Jul;83(13):6391-403. doi: 10.1128/JVI.00061-09. Epub 2009 Apr 15.

14.
15.

Human cytomegalovirus utilises cellular dual-specificity tyrosine phosphorylation-regulated kinases during placental replication.

Hamilton ST, Hutterer C, Egilmezer E, Steingruber M, Milbradt J, Marschall M, Rawlinson WD.

Placenta. 2018 Dec;72-73:10-19. doi: 10.1016/j.placenta.2018.10.002. Epub 2018 Oct 13.

PMID:
30501876
16.

Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest.

Reitsma JM, Savaryn JP, Faust K, Sato H, Halligan BD, Terhune SS.

Cell Host Microbe. 2011 Feb 17;9(2):103-14. doi: 10.1016/j.chom.2011.01.006.

17.

Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection.

Soroceanu L, Akhavan A, Cobbs CS.

Nature. 2008 Sep 18;455(7211):391-5. doi: 10.1038/nature07209. Epub 2008 Aug 13.

PMID:
18701889
18.
19.

Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny.

McArdle J, Schafer XL, Munger J.

J Virol. 2011 Jan;85(2):705-14. doi: 10.1128/JVI.01557-10. Epub 2010 Nov 17. Erratum in: J Virol. 2013 Jun;87(12):7197.

20.

Inhibition of IKKα by BAY61-3606 Reveals IKKα-Dependent Histone H3 Phosphorylation in Human Cytomegalovirus Infected Cells.

Ho CM, Donovan-Banfield IZ, Tan L, Zhang T, Gray NS, Strang BL.

PLoS One. 2016 Mar 1;11(3):e0150339. doi: 10.1371/journal.pone.0150339. eCollection 2016.

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