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Items: 1 to 20 of 103

1.

A caveolae-targeted L-type Ca²+ channel antagonist inhibits hypertrophic signaling without reducing cardiac contractility.

Makarewich CA, Correll RN, Gao H, Zhang H, Yang B, Berretta RM, Rizzo V, Molkentin JD, Houser SR.

Circ Res. 2012 Mar 2;110(5):669-74. doi: 10.1161/CIRCRESAHA.111.264028. Epub 2012 Feb 2.

2.

Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling.

Gao H, Wang F, Wang W, Makarewich CA, Zhang H, Kubo H, Berretta RM, Barr LA, Molkentin JD, Houser SR.

J Mol Cell Cardiol. 2012 Nov;53(5):657-67. doi: 10.1016/j.yjmcc.2012.08.005. Epub 2012 Aug 21.

3.

{beta}1-Adrenergic receptor activation induces mouse cardiac myocyte death through both L-type calcium channel-dependent and -independent pathways.

Wang W, Zhang H, Gao H, Kubo H, Berretta RM, Chen X, Houser SR.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H322-31. doi: 10.1152/ajpheart.00392.2010. Epub 2010 May 21.

4.

Caveolin-3 Overexpression Attenuates Cardiac Hypertrophy via Inhibition of T-type Ca2+ Current Modulated by Protein Kinase Cα in Cardiomyocytes.

Markandeya YS, Phelan LJ, Woon MT, Keefe AM, Reynolds CR, August BK, Hacker TA, Roth DM, Patel HH, Balijepalli RC.

J Biol Chem. 2015 Sep 4;290(36):22085-100. doi: 10.1074/jbc.M115.674945. Epub 2015 Jul 13.

5.

Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy.

Chen X, Nakayama H, Zhang X, Ai X, Harris DM, Tang M, Zhang H, Szeto C, Stockbower K, Berretta RM, Eckhart AD, Koch WJ, Molkentin JD, Houser SR.

J Mol Cell Cardiol. 2011 Mar;50(3):460-70. doi: 10.1016/j.yjmcc.2010.11.012. Epub 2010 Nov 25.

6.

Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation.

Balijepalli RC, Foell JD, Hall DD, Hell JW, Kamp TJ.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7500-5. Epub 2006 Apr 28.

7.

Caveolae modulate excitation-contraction coupling and beta2-adrenergic signalling in adult rat ventricular myocytes.

Calaghan S, White E.

Cardiovasc Res. 2006 Mar 1;69(4):816-24. Epub 2005 Nov 28.

PMID:
16318846
8.

Caveolae-specific activation loop between CaMKII and L-type Ca2+ channel aggravates cardiac hypertrophy in α1-adrenergic stimulation.

Tonegawa K, Otsuka W, Kumagai S, Matsunami S, Hayamizu N, Tanaka S, Moriwaki K, Obana M, Maeda M, Asahi M, Kiyonari H, Fujio Y, Nakayama H.

Am J Physiol Heart Circ Physiol. 2017 Mar 1;312(3):H501-H514. doi: 10.1152/ajpheart.00601.2016. Epub 2016 Dec 30.

PMID:
28039202
9.

Different subcellular populations of L-type Ca2+ channels exhibit unique regulation and functional roles in cardiomyocytes.

Best JM, Kamp TJ.

J Mol Cell Cardiol. 2012 Feb;52(2):376-87. doi: 10.1016/j.yjmcc.2011.08.014. Epub 2011 Aug 23. Review.

10.

Ca2+ influx through T- and L-type Ca2+ channels have different effects on myocyte contractility and induce unique cardiac phenotypes.

Jaleel N, Nakayama H, Chen X, Kubo H, MacDonnell S, Zhang H, Berretta R, Robbins J, Cribbs L, Molkentin JD, Houser SR.

Circ Res. 2008 Nov 7;103(10):1109-19. doi: 10.1161/CIRCRESAHA.108.185611. Epub 2008 Oct 2.

11.

Low-dose combination of Rho kinase and L-type Ca(2+) channel antagonists for selective inhibition of depolarization-induced sustained arterial contraction.

Porras-González C, González-Rodríguez P, Calderón-Sánchez E, López-Barneo J, Ureña J.

Eur J Pharmacol. 2014 Jun 5;732:130-8. doi: 10.1016/j.ejphar.2014.02.046. Epub 2014 Mar 27.

PMID:
24680953
12.

Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling.

Horikawa YT, Panneerselvam M, Kawaraguchi Y, Tsutsumi YM, Ali SS, Balijepalli RC, Murray F, Head BP, Niesman IR, Rieg T, Vallon V, Insel PA, Patel HH, Roth DM.

J Am Coll Cardiol. 2011 May 31;57(22):2273-83. doi: 10.1016/j.jacc.2010.12.032.

13.

L-type calcium channel targeting and local signalling in cardiac myocytes.

Shaw RM, Colecraft HM.

Cardiovasc Res. 2013 May 1;98(2):177-86. doi: 10.1093/cvr/cvt021. Epub 2013 Feb 14. Review.

14.

Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca2+ handling and calcineurin-NFAT signaling pathway.

Ding W, Dong M, Deng J, Yan D, Liu Y, Xu T, Liu J.

Am J Physiol Heart Circ Physiol. 2014 Sep 1;307(5):H792-802. doi: 10.1152/ajpheart.00017.2014. Epub 2014 Jul 11.

PMID:
25015961
15.

MDIMP, a novel cardiac Ca(2+) channel blocker with atrial selectivity.

Santamaria-Herrera MA, Ríos-Pérez EB, de la Rosa JA, García-Castañeda M, Osornio-Garduño DS, Ramos-Mondragón R, Mancilla-Percino T, Avila G.

Eur J Pharmacol. 2016 Jun 15;781:218-28. doi: 10.1016/j.ejphar.2016.04.027. Epub 2016 Apr 21.

PMID:
27089820
16.

Serotonin 5-HT2A receptor-mediated hypertrophy is negatively regulated by caveolin-3 in cardiomyoblasts and neonatal cardiomyocytes.

Mialet-Perez J, D'Angelo R, Villeneuve C, Ordener C, Nègre-Salvayre A, Parini A, Vindis C.

J Mol Cell Cardiol. 2012 Feb;52(2):502-10. doi: 10.1016/j.yjmcc.2011.07.019. Epub 2011 Jul 28.

PMID:
21820441
17.

Basal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700.

Fu Y, Westenbroek RE, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16598-603. doi: 10.1073/pnas.1419129111. Epub 2014 Nov 3.

18.

The Ca(v)3.2 T-type Ca(2+) channel is required for pressure overload-induced cardiac hypertrophy in mice.

Chiang CS, Huang CH, Chieng H, Chang YT, Chang D, Chen JJ, Chen YC, Chen YH, Shin HS, Campbell KP, Chen CC.

Circ Res. 2009 Feb 27;104(4):522-30. doi: 10.1161/CIRCRESAHA.108.184051. Epub 2009 Jan 2.

19.

Caveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels.

Markandeya YS, Fahey JM, Pluteanu F, Cribbs LL, Balijepalli RC.

J Biol Chem. 2011 Jan 28;286(4):2433-44. doi: 10.1074/jbc.M110.182550. Epub 2010 Nov 17.

20.

Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current.

Qi XY, Yeh YH, Xiao L, Burstein B, Maguy A, Chartier D, Villeneuve LR, Brundel BJ, Dobrev D, Nattel S.

Circ Res. 2008 Oct 10;103(8):845-54. doi: 10.1161/CIRCRESAHA.108.175463. Epub 2008 Aug 21.

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