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Decreased intrinsic brain connectivity is associated with reduced clinical pain in fibromyalgia.

Napadow V, Kim J, Clauw DJ, Harris RE.

Arthritis Rheum. 2012 Jul;64(7):2398-403. doi: 10.1002/art.34412.


Intrinsic brain connectivity in fibromyalgia is associated with chronic pain intensity.

Napadow V, LaCount L, Park K, As-Sanie S, Clauw DJ, Harris RE.

Arthritis Rheum. 2010 Aug;62(8):2545-55. doi: 10.1002/art.27497.


Altered insula-default mode network connectivity in fibromyalgia: a resting-state magnetoencephalographic study.

Hsiao FJ, Wang SJ, Lin YY, Fuh JL, Ko YC, Wang PN, Chen WT.

J Headache Pain. 2017 Aug 23;18(1):89. doi: 10.1186/s10194-017-0799-x.


Fibromyalgia is associated with decreased connectivity between pain- and sensorimotor brain areas.

Flodin P, Martinsen S, Löfgren M, Bileviciute-Ljungar I, Kosek E, Fransson P.

Brain Connect. 2014 Oct;4(8):587-94. doi: 10.1089/brain.2014.0274. Epub 2014 Aug 7.


The contribution of sensory system functional connectivity reduction to clinical pain in fibromyalgia.

Pujol J, Macià D, Garcia-Fontanals A, Blanco-Hinojo L, López-Solà M, Garcia-Blanco S, Poca-Dias V, Harrison BJ, Contreras-Rodríguez O, Monfort J, Garcia-Fructuoso F, Deus J.

Pain. 2014 Aug;155(8):1492-503. doi: 10.1016/j.pain.2014.04.028. Epub 2014 May 2.


Normalization of aberrant resting state functional connectivity in fibromyalgia patients following a three month physical exercise therapy.

Flodin P, Martinsen S, Mannerkorpi K, Löfgren M, Bileviciute-Ljungar I, Kosek E, Fransson P.

Neuroimage Clin. 2015 Aug 18;9:134-9. doi: 10.1016/j.nicl.2015.08.004. eCollection 2015.


Disrupted functional connectivity of the pain network in fibromyalgia.

Cifre I, Sitges C, Fraiman D, Muñoz MÁ, Balenzuela P, González-Roldán A, Martínez-Jauand M, Birbaumer N, Chialvo DR, Montoya P.

Psychosom Med. 2012 Jan;74(1):55-62. doi: 10.1097/PSY.0b013e3182408f04. Epub 2011 Dec 30.


Increased power spectral density in resting-state pain-related brain networks in fibromyalgia.

Kim JY, Kim SH, Seo J, Kim SH, Han SW, Nam EJ, Kim SK, Lee HJ, Lee SJ, Kim YT, Chang Y.

Pain. 2013 Sep;154(9):1792-7. doi: 10.1016/j.pain.2013.05.040. Epub 2013 May 25.


Resting state connectivity correlates with drug and placebo response in fibromyalgia patients.

Schmidt-Wilcke T, Ichesco E, Hampson JP, Kairys A, Peltier S, Harte S, Clauw DJ, Harris RE.

Neuroimage Clin. 2014 Sep 16;6:252-61. doi: 10.1016/j.nicl.2014.09.007. eCollection 2014.


Altered resting state connectivity of the insular cortex in individuals with fibromyalgia.

Ichesco E, Schmidt-Wilcke T, Bhavsar R, Clauw DJ, Peltier SJ, Kim J, Napadow V, Hampson JP, Kairys AE, Williams DA, Harris RE.

J Pain. 2014 Aug;15(8):815-826.e1. doi: 10.1016/j.jpain.2014.04.007. Epub 2014 May 9.


Overlapping structural and functional brain changes in patients with long-term exposure to fibromyalgia pain.

Jensen KB, Srinivasan P, Spaeth R, Tan Y, Kosek E, Petzke F, Carville S, Fransson P, Marcus H, Williams SC, Choy E, Vitton O, Gracely R, Ingvar M, Kong J.

Arthritis Rheum. 2013 Dec;65(12):3293-303. doi: 10.1002/art.38170.


Aberrant intrinsic brain activity and cognitive deficit in first-episode treatment-naive patients with schizophrenia.

He Z, Deng W, Li M, Chen Z, Jiang L, Wang Q, Huang C, Collier DA, Gong Q, Ma X, Zhang N, Li T.

Psychol Med. 2013 Apr;43(4):769-80. doi: 10.1017/S0033291712001638. Epub 2012 Aug 10.


Effects of Cognitive-Behavioral Therapy (CBT) on Brain Connectivity Supporting Catastrophizing in Fibromyalgia.

Lazaridou A, Kim J, Cahalan CM, Loggia ML, Franceschelli O, Berna C, Schur P, Napadow V, Edwards RR.

Clin J Pain. 2017 Mar;33(3):215-221. doi: 10.1097/AJP.0000000000000422.


Functional Connectivity with the Default Mode Network Is Altered in Fibromyalgia Patients.

Fallon N, Chiu Y, Nurmikko T, Stancak A.

PLoS One. 2016 Jul 21;11(7):e0159198. doi: 10.1371/journal.pone.0159198. eCollection 2016.


The somatosensory link in fibromyalgia: functional connectivity of the primary somatosensory cortex is altered by sustained pain and is associated with clinical/autonomic dysfunction.

Kim J, Loggia ML, Cahalan CM, Harris RE, Beissner F Dr Phil Nat, Garcia RG, Kim H, Wasan AD, Edwards RR, Napadow V.

Arthritis Rheumatol. 2015 May;67(5):1395-1405. doi: 10.1002/art.39043.


Dynamic levels of glutamate within the insula are associated with improvements in multiple pain domains in fibromyalgia.

Harris RE, Sundgren PC, Pang Y, Hsu M, Petrou M, Kim SH, McLean SA, Gracely RH, Clauw DJ.

Arthritis Rheum. 2008 Mar;58(3):903-7. doi: 10.1002/art.23223.


Acupuncture treatment of chronic low back pain reverses an abnormal brain default mode network in correlation with clinical pain relief.

Li J, Zhang JH, Yi T, Tang WJ, Wang SW, Dong JC.

Acupunct Med. 2014 Apr;32(2):102-8. doi: 10.1136/acupmed-2013-010423. Epub 2013 Nov 26.


Functional network connectivity of pain-related resting state networks in somatoform pain disorder: an exploratory fMRI study.

Otti A, Guendel H, Henningsen P, Zimmer C, Wohlschlaeger AM, Noll-Hussong M.

J Psychiatry Neurosci. 2013 Jan;38(1):57-65. doi: 10.1503/jpn.110187.


Central sensitization in fibromyalgia? A systematic review on structural and functional brain MRI.

Cagnie B, Coppieters I, Denecker S, Six J, Danneels L, Meeus M.

Semin Arthritis Rheum. 2014 Aug;44(1):68-75. doi: 10.1016/j.semarthrit.2014.01.001. Epub 2014 Jan 8. Review.


Noxious somatosensory stimulation affects the default mode of brain function: evidence from functional MR imaging.

Mantini D, Caulo M, Ferretti A, Romani GL, Tartaro A.

Radiology. 2009 Dec;253(3):797-804. doi: 10.1148/radiol.2533090602. Epub 2009 Sep 29.


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