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Items: 1 to 20 of 164

1.

Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy.

Chen G, Bradford WD, Seidel CW, Li R.

Nature. 2012 Jan 29;482(7384):246-50. doi: 10.1038/nature10795.

2.

Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast.

Pavelka N, Rancati G, Zhu J, Bradford WD, Saraf A, Florens L, Sanderson BW, Hattem GL, Li R.

Nature. 2010 Nov 11;468(7321):321-5. doi: 10.1038/nature09529. Epub 2010 Oct 20.

3.

Genetic architecture of Hsp90-dependent drug resistance.

Cowen LE, Carpenter AE, Matangkasombut O, Fink GR, Lindquist S.

Eukaryot Cell. 2006 Dec;5(12):2184-8. Epub 2006 Oct 20.

4.

Sgt1 associates with Hsp90: an initial step of assembly of the core kinetochore complex.

Bansal PK, Abdulle R, Kitagawa K.

Mol Cell Biol. 2004 Sep;24(18):8069-79.

5.

Aneuploidy causes proteotoxic stress in yeast.

Oromendia AB, Dodgson SE, Amon A.

Genes Dev. 2012 Dec 15;26(24):2696-708. doi: 10.1101/gad.207407.112. Epub 2012 Dec 7.

6.

Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi.

Cowen LE, Lindquist S.

Science. 2005 Sep 30;309(5744):2185-9.

7.

Whole chromosome aneuploidy: big mutations drive adaptation by phenotypic leap.

Chen G, Rubinstein B, Li R.

Bioessays. 2012 Oct;34(10):893-900. doi: 10.1002/bies.201200069. Epub 2012 Aug 24.

8.

The Hsp90 molecular chaperone complex regulates maltose induction and stability of the Saccharomyces MAL gene transcription activator Mal63p.

Bali M, Zhang B, Morano KA, Michels CA.

J Biol Chem. 2003 Nov 28;278(48):47441-8. Epub 2003 Sep 18.

9.

Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations.

Hill JA, Ammar R, Torti D, Nislow C, Cowen LE.

PLoS Genet. 2013 Apr;9(4):e1003390. doi: 10.1371/journal.pgen.1003390. Epub 2013 Apr 4.

10.

Hsp90 regulates nongenetic variation in response to environmental stress.

Hsieh YY, Hung PH, Leu JY.

Mol Cell. 2013 Apr 11;50(1):82-92. doi: 10.1016/j.molcel.2013.01.026. Epub 2013 Feb 21.

11.

The Hsp90/Cdc37p chaperone system is a determinant of molybdate resistance in Saccharomyces cerevisiae.

Millson SH, Nuttall JM, Mollapour M, Piper PW.

Yeast. 2009 Jun;26(6):339-47. doi: 10.1002/yea.1670.

12.

Sgt1 dimerization is required for yeast kinetochore assembly.

Bansal PK, Nourse A, Abdulle R, Kitagawa K.

J Biol Chem. 2009 Feb 6;284(6):3586-92. doi: 10.1074/jbc.M806281200. Epub 2008 Dec 10.

13.

Karyotypic determinants of chromosome instability in aneuploid budding yeast.

Zhu J, Pavelka N, Bradford WD, Rancati G, Li R.

PLoS Genet. 2012;8(5):e1002719. doi: 10.1371/journal.pgen.1002719. Epub 2012 May 17.

14.

Expressed in the yeast Saccharomyces cerevisiae, human ERK5 is a client of the Hsp90 chaperone that complements loss of the Slt2p (Mpk1p) cell integrity stress-activated protein kinase.

Truman AW, Millson SH, Nuttall JM, King V, Mollapour M, Prodromou C, Pearl LH, Piper PW.

Eukaryot Cell. 2006 Nov;5(11):1914-24. Epub 2006 Sep 1.

15.

The yeast Hsp110 family member, Sse1, is an Hsp90 cochaperone.

Liu XD, Morano KA, Thiele DJ.

J Biol Chem. 1999 Sep 17;274(38):26654-60.

16.

The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification.

Covo S, Puccia CM, Argueso JL, Gordenin DA, Resnick MA.

Genetics. 2014 Feb;196(2):373-84. doi: 10.1534/genetics.113.159202. Epub 2013 Dec 2.

17.

Protein folding sculpting evolutionary change.

Lindquist S.

Cold Spring Harb Symp Quant Biol. 2009;74:103-8. doi: 10.1101/sqb.2009.74.043. Epub 2010 Apr 7. Review.

PMID:
20375316
18.

Nonapoptotic death of Saccharomyces cerevisiae cells that is stimulated by Hsp90 and inhibited by calcineurin and Cmk2 in response to endoplasmic reticulum stresses.

Dudgeon DD, Zhang N, Ositelu OO, Kim H, Cunningham KW.

Eukaryot Cell. 2008 Dec;7(12):2037-51. doi: 10.1128/EC.00291-08. Epub 2008 Sep 19.

19.

Metabolic control of antifungal drug resistance.

Robbins N, Collins C, Morhayim J, Cowen LE.

Fungal Genet Biol. 2010 Feb;47(2):81-93. doi: 10.1016/j.fgb.2009.07.004. Epub 2009 Jul 10.

PMID:
19595784
20.

Identification of an Hsp90 mutation that selectively disrupts cAMP/PKA signaling in Saccharomyces cerevisiae.

Flom GA, Langner E, Johnson JL.

Curr Genet. 2012 Jun;58(3):149-63. doi: 10.1007/s00294-012-0373-7. Epub 2012 Mar 30.

PMID:
22461145

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