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Items: 1 to 20 of 239

1.

PGC-1α induces mitochondrial and myokine transcriptional programs and lipid droplet and glycogen accumulation in cultured human skeletal muscle cells.

Mormeneo E, Jimenez-Mallebrera C, Palomer X, De Nigris V, Vázquez-Carrera M, Orozco A, Nascimento A, Colomer J, Lerín C, Gómez-Foix AM.

PLoS One. 2012;7(1):e29985. doi: 10.1371/journal.pone.0029985. Epub 2012 Jan 17.

2.

Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals.

Consitt LA, Bell JA, Koves TR, Muoio DM, Hulver MW, Haynie KR, Dohm GL, Houmard JA.

Diabetes. 2010 Jun;59(6):1407-15. doi: 10.2337/db09-1704. Epub 2010 Mar 3.

3.

PGC-1{alpha} is required for AICAR-induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle.

Leick L, Fentz J, Biensø RS, Knudsen JG, Jeppesen J, Kiens B, Wojtaszewski JF, Pilegaard H.

Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E456-65. doi: 10.1152/ajpendo.00648.2009. Epub 2010 Jul 13.

PMID:
20628026
4.

Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.

Summermatter S, Baum O, Santos G, Hoppeler H, Handschin C.

J Biol Chem. 2010 Oct 22;285(43):32793-800. doi: 10.1074/jbc.M110.145995. Epub 2010 Aug 17.

5.

PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein.

Holloway GP, Perry CG, Thrush AB, Heigenhauser GJ, Dyck DJ, Bonen A, Spriet LL.

Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1060-9. doi: 10.1152/ajpendo.00726.2007. Epub 2008 Mar 18.

PMID:
18349111
6.
7.

PGC-1alpha and PGC-1beta have both similar and distinct effects on myofiber switching toward an oxidative phenotype.

Mortensen OH, Frandsen L, Schjerling P, Nishimura E, Grunnet N.

Am J Physiol Endocrinol Metab. 2006 Oct;291(4):E807-16. Epub 2006 May 23.

PMID:
16720625
8.

Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats.

Benton CR, Holloway GP, Han XX, Yoshida Y, Snook LA, Lally J, Glatz JF, Luiken JJ, Chabowski A, Bonen A.

Diabetologia. 2010 Sep;53(9):2008-19. doi: 10.1007/s00125-010-1773-1. Epub 2010 May 20.

PMID:
20490453
9.

PGC-1alpha-induced improvements in skeletal muscle metabolism and insulin sensitivity.

Bonen A.

Appl Physiol Nutr Metab. 2009 Jun;34(3):307-14. doi: 10.1139/H09-008. Review.

PMID:
19448691
10.

A role for the transcriptional coactivator PGC-1alpha in muscle refueling.

Wende AR, Schaeffer PJ, Parker GJ, Zechner C, Han DH, Chen MM, Hancock CR, Lehman JJ, Huss JM, McClain DA, Holloszy JO, Kelly DP.

J Biol Chem. 2007 Dec 14;282(50):36642-51. Epub 2007 Oct 11.

11.

The importance of PGC-1α in contractile activity-induced mitochondrial adaptations.

Uguccioni G, Hood DA.

Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E361-71. doi: 10.1152/ajpendo.00292.2010. Epub 2010 Nov 16.

PMID:
21081705
14.

Striated muscle activator of Rho signalling (STARS) is a PGC-1α/oestrogen-related receptor-α target gene and is upregulated in human skeletal muscle after endurance exercise.

Wallace MA, Hock MB, Hazen BC, Kralli A, Snow RJ, Russell AP.

J Physiol. 2011 Apr 15;589(Pt 8):2027-39. doi: 10.1113/jphysiol.2011.205468. Epub 2011 Feb 21.

15.

Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.

Wu Z, Huang X, Feng Y, Handschin C, Feng Y, Gullicksen PS, Bare O, Labow M, Spiegelman B, Stevenson SC.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14379-84. Epub 2006 Sep 15.

16.

Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in cultured myotubes.

Espinoza DO, Boros LG, Crunkhorn S, Gami H, Patti ME.

FASEB J. 2010 Apr;24(4):1003-14. doi: 10.1096/fj.09-133728. Epub 2009 Nov 11.

17.

Overexpression of PGC-1β improves insulin sensitivity and mitochondrial function in 3T3-L1 adipocytes.

Gao CL, Liu GL, Liu S, Chen XH, Ji CB, Zhang CM, Xia ZK, Guo XR.

Mol Cell Biochem. 2011 Jul;353(1-2):215-23. doi: 10.1007/s11010-011-0789-2. Epub 2011 Apr 16.

PMID:
21499715
18.

Bhlhe40 Represses PGC-1α Activity on Metabolic Gene Promoters in Myogenic Cells.

Chung SY, Kao CH, Villarroya F, Chang HY, Chang HC, Hsiao SP, Liou GG, Chen SL.

Mol Cell Biol. 2015 Jul;35(14):2518-29. doi: 10.1128/MCB.00387-15. Epub 2015 May 11.

19.

The role of PGC-1alpha on mitochondrial function and apoptotic susceptibility in muscle.

Adhihetty PJ, Uguccioni G, Leick L, Hidalgo J, Pilegaard H, Hood DA.

Am J Physiol Cell Physiol. 2009 Jul;297(1):C217-25. doi: 10.1152/ajpcell.00070.2009. Epub 2009 May 13.

PMID:
19439529
20.

Skeletal muscle-specific expression of PGC-1α-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake.

Tadaishi M, Miura S, Kai Y, Kano Y, Oishi Y, Ezaki O.

PLoS One. 2011;6(12):e28290. doi: 10.1371/journal.pone.0028290. Epub 2011 Dec 8.

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