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Items: 1 to 20 of 117

1.

Effect of cigarette smoke exposure and structural modifications on the α-1 Antitrypsin interaction with caspases.

Lockett AD, Van Demark M, Gu Y, Schweitzer KS, Sigua N, Kamocki K, Fijalkowska I, Garrison J, Fisher AJ, Serban K, Wise RA, Flotte TR, Mueller C, Presson RG Jr, Petrache HI, Tuder RM, Petrache I.

Mol Med. 2012 May 9;18:445-54. doi: 10.2119/molmed.2011.00207.

2.

alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis.

Petrache I, Fijalkowska I, Medler TR, Skirball J, Cruz P, Zhen L, Petrache HI, Flotte TR, Tuder RM.

Am J Pathol. 2006 Oct;169(4):1155-66.

3.

Lung disease associated with alpha1-antitrypsin deficiency.

Tuder RM, Janciauskiene SM, Petrache I.

Proc Am Thorac Soc. 2010 Nov;7(6):381-6. doi: 10.1513/pats.201002-020AW. Review.

4.

Alpha-1 Antitrypsin and Lung Cell Apoptosis.

Serban KA, Petrache I.

Ann Am Thorac Soc. 2016 Apr;13 Suppl 2:S146-9. doi: 10.1513/AnnalsATS.201505-312KV.

PMID:
27115949
5.

Mechanism of alpha-1 antitrypsin endocytosis by lung endothelium.

Sohrab S, Petrusca DN, Lockett AD, Schweitzer KS, Rush NI, Gu Y, Kamocki K, Garrison J, Petrache I.

FASEB J. 2009 Sep;23(9):3149-58. doi: 10.1096/fj.09-129304.

6.

Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells.

Lockett AD, Petrusca DN, Justice MJ, Poirier C, Serban KA, Rush NI, Kamocka M, Predescu D, Predescu S, Petrache I.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 15;309(4):L425-34. doi: 10.1152/ajplung.00376.2014.

7.
8.

TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema.

An CH, Wang XM, Lam HC, Ifedigbo E, Washko GR, Ryter SW, Choi AM.

Am J Physiol Lung Cell Mol Physiol. 2012 Nov 1;303(9):L748-57. doi: 10.1152/ajplung.00102.2012.

9.

α1-Antitrypsin activates protein phosphatase 2A to counter lung inflammatory responses.

Geraghty P, Eden E, Pillai M, Campos M, McElvaney NG, Foronjy RF.

Am J Respir Crit Care Med. 2014 Dec 1;190(11):1229-42. doi: 10.1164/rccm.201405-0872OC.

10.

alpha-1-Antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse.

Churg A, Wang RD, Xie C, Wright JL.

Am J Respir Crit Care Med. 2003 Jul 15;168(2):199-207.

PMID:
12689849
11.

T cell depletion protects against alveolar destruction due to chronic cigarette smoke exposure in mice.

Podolin PL, Foley JP, Carpenter DC, Bolognese BJ, Logan GA, Long E 3rd, Harrison OJ, Walsh PT.

Am J Physiol Lung Cell Mol Physiol. 2013 Mar 1;304(5):L312-23. doi: 10.1152/ajplung.00152.2012.

12.
13.

Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice.

Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AÖ, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, Twigg HL 3rd, Presson RG, Sethi S, Petrache I.

J Clin Invest. 2011 Jun;121(6):2470-9. doi: 10.1172/JCI43881. Erratum in: J Clin Invest. 2012 Jul 2;122(7):2703.

14.

Alpha 1-antitrypsin does not inhibit human monocyte caspase-1.

Rahman MA, Mitra S, Sarkar A, Wewers MD.

PLoS One. 2015 Feb 6;10(2):e0117330. doi: 10.1371/journal.pone.0117330.

15.

Alpha1-antitrypsin suppresses TNF-alpha and MMP-12 production by cigarette smoke-stimulated macrophages.

Churg A, Wang X, Wang RD, Meixner SC, Pryzdial EL, Wright JL.

Am J Respir Cell Mol Biol. 2007 Aug;37(2):144-51.

PMID:
17395890
16.

Protective role for club cell secretory protein-16 (CC16) in the development of COPD.

Laucho-Contreras ME, Polverino F, Gupta K, Taylor KL, Kelly E, Pinto-Plata V, Divo M, Ashfaq N, Petersen H, Stripp B, Pilon AL, Tesfaigzi Y, Celli BR, Owen CA.

Eur Respir J. 2015 Jun;45(6):1544-56. doi: 10.1183/09031936.00134214.

17.

Active trafficking of alpha 1 antitrypsin across the lung endothelium.

Lockett AD, Brown MB, Santos-Falcon N, Rush NI, Oueini H, Oberle AJ, Bolanis E, Fragoso MA, Petrusca DN, Serban KA, Schweitzer KS, Presson RG Jr, Campos M, Petrache I.

PLoS One. 2014 Apr 17;9(4):e93979. doi: 10.1371/journal.pone.0093979.

18.

Alpha(1)-antitrypsin inhibits epithelial Na+ transport in vitro and in vivo.

Lazrak A, Nita I, Subramaniyam D, Wei S, Song W, Ji HL, Janciauskiene S, Matalon S.

Am J Respir Cell Mol Biol. 2009 Sep;41(3):261-70. doi: 10.1165/rcmb.2008-0384OC.

19.

A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema.

Petrache I, Fijalkowska I, Zhen L, Medler TR, Brown E, Cruz P, Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Shapiro L, Zhang B, Song S, Hicklin D, Voelkel NF, Flotte T, Tuder RM.

Am J Respir Crit Care Med. 2006 Jun 1;173(11):1222-8.

20.

[Analysis of alpha-1-antitrypsin phenotypes and genotypes in patients with early-onset pulmonary emphysema].

Dwomiczak S, Ziora D, Konofalski L, Szalaty M, Kowalska A, Kozielski J.

Pneumonol Alergol Pol. 2005;73(1):12-7. Polish.

PMID:
16539178
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