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A high-fat diet containing whole walnuts (Juglans regia) reduces tumour size and growth along with plasma insulin-like growth factor 1 in the transgenic adenocarcinoma of the mouse prostate model.

Davis PA, Vasu VT, Gohil K, Kim H, Khan IH, Cross CE, Yokoyama W.

Br J Nutr. 2012 Nov 28;108(10):1764-72. doi: 10.1017/S0007114511007288. Epub 2012 Jan 16.


TRAMP prostate tumor growth is slowed by walnut diets through altered IGF-1 levels, energy pathways, and cholesterol metabolism.

Kim H, Yokoyama W, Davis PA.

J Med Food. 2014 Dec;17(12):1281-6. doi: 10.1089/jmf.2014.0061.


Walnuts reduce aortic ET-1 mRNA levels in hamsters fed a high-fat, atherogenic diet.

Davis P, Valacchi G, Pagnin E, Shao Q, Gross HB, Calo L, Yokoyama W.

J Nutr. 2006 Feb;136(2):428-32.


Consumption of Walnuts in Combination with Other Whole Foods Produces Physiologic, Metabolic, and Gene Expression Changes in Obese C57BL/6J High-Fat-Fed Male Mice.

Luo T, Miranda-Garcia O, Adamson A, Hamilton-Reeves J, Sullivan DK, Kinchen JM, Shay NF.

J Nutr. 2016 Sep;146(9):1641-50. doi: 10.3945/jn.116.234419. Epub 2016 Aug 3.


Fish oil slows prostate cancer xenograft growth relative to other dietary fats and is associated with decreased mitochondrial and insulin pathway gene expression.

Lloyd JC, Masko EM, Wu C, Keenan MM, Pilla DM, Aronson WJ, Chi JT, Freedland SJ.

Prostate Cancer Prostatic Dis. 2013 Dec;16(4):285-91. doi: 10.1038/pcan.2013.19. Epub 2013 Jul 23.


A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects.

Chisholm A, Mann J, Skeaff M, Frampton C, Sutherland W, Duncan A, Tiszavari S.

Eur J Clin Nutr. 1998 Jan;52(1):12-6.


An acute intake of a walnut-enriched meal improves postprandial adiponectin response in healthy young adults.

Lozano A, Perez-Martinez P, Marin C, Tinahones FJ, Delgado-Lista J, Cruz-Teno C, Gomez-Luna P, Rodriguez-Cantalejo F, Perez-Jimenez F, Lopez-Miranda J.

Nutr Res. 2013 Dec;33(12):1012-8. doi: 10.1016/j.nutres.2013.08.010. Epub 2013 Oct 9.


The effects of varying dietary carbohydrate and fat content on survival in a murine LNCaP prostate cancer xenograft model.

Mavropoulos JC, Buschemeyer WC 3rd, Tewari AK, Rokhfeld D, Pollak M, Zhao Y, Febbo PG, Cohen P, Hwang D, Devi G, Demark-Wahnefried W, Westman EC, Peterson BL, Pizzo SV, Freedland SJ.

Cancer Prev Res (Phila). 2009 Jun;2(6):557-65. doi: 10.1158/1940-6207.CAPR-08-0188. Epub 2009 May 26.


E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse.

Wechter WJ, Leipold DD, Murray ED Jr, Quiggle D, McCracken JD, Barrios RS, Greenberg NM.

Cancer Res. 2000 Apr 15;60(8):2203-8.


Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis.

Freedland SJ, Mavropoulos J, Wang A, Darshan M, Demark-Wahnefried W, Aronson WJ, Cohen P, Hwang D, Peterson B, Fields T, Pizzo SV, Isaacs WB.

Prostate. 2008 Jan 1;68(1):11-9.


Long-term effects of increased dietary polyunsaturated fat from walnuts on metabolic parameters in type II diabetes.

Tapsell LC, Batterham MJ, Teuss G, Tan SY, Dalton S, Quick CJ, Gillen LJ, Charlton KE.

Eur J Clin Nutr. 2009 Aug;63(8):1008-15. doi: 10.1038/ejcn.2009.19. Epub 2009 Apr 8.


The effect of dietary walnuts compared to fatty fish on eicosanoids, cytokines, soluble endothelial adhesion molecules and lymphocyte subsets: a randomized, controlled crossover trial.

Chiang YL, Haddad E, Rajaram S, Shavlik D, Sabaté J.

Prostaglandins Leukot Essent Fatty Acids. 2012 Oct-Nov;87(4-5):111-7. doi: 10.1016/j.plefa.2012.07.007. Epub 2012 Sep 5.


Including walnuts in a low-fat/modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes.

Tapsell LC, Gillen LJ, Patch CS, Batterham M, Owen A, Baré M, Kennedy M.

Diabetes Care. 2004 Dec;27(12):2777-83.


Association of diet-induced hyperinsulinemia with accelerated growth of prostate cancer (LNCaP) xenografts.

Venkateswaran V, Haddad AQ, Fleshner NE, Fan R, Sugar LM, Nam R, Klotz LH, Pollak M.

J Natl Cancer Inst. 2007 Dec 5;99(23):1793-800. Epub 2007 Nov 27.


Walnuts Consumed by Healthy Adults Provide Less Available Energy than Predicted by the Atwater Factors.

Baer DJ, Gebauer SK, Novotny JA.

J Nutr. 2016 Jan;146(1):9-13. doi: 10.3945/jn.115.217372. Epub 2015 Nov 18.


Dietary methionine restriction inhibits prostatic intraepithelial neoplasia in TRAMP mice.

Sinha R, Cooper TK, Rogers CJ, Sinha I, Turbitt WJ, Calcagnotto A, Perrone CE, Richie JP Jr.

Prostate. 2014 Dec;74(16):1663-73. doi: 10.1002/pros.22884. Epub 2014 Sep 22.


Insulin-Like growth factor 1 related pathways and high-fat diet promotion of transgenic adenocarcinoma mouse prostate (TRAMP) cancer progression.

Xu H, Jiang HW, Ding Q.

Actas Urol Esp. 2015 Apr;39(3):161-8. doi: 10.1016/j.acuro.2014.05.014. Epub 2014 Oct 28. English, Spanish.


Nutrient displacement associated with walnut supplementation in men.

Kranz S, Hill AM, Fleming JA, Hartman TJ, West SG, Kris-Etherton PM.

J Hum Nutr Diet. 2014 Apr;27 Suppl 2:247-54. doi: 10.1111/jhn.12146. Epub 2013 Aug 24.


Effects of short-term walnut consumption on human microvascular function and its relationship to plasma epoxide content.

Holt RR, Yim SJ, Shearer GC, Hackman RM, Djurica D, Newman JW, Shindel AW, Keen CL.

J Nutr Biochem. 2015 Dec;26(12):1458-66. doi: 10.1016/j.jnutbio.2015.07.012. Epub 2015 Aug 1.


Chronic and acute effects of walnuts on antioxidant capacity and nutritional status in humans: a randomized, cross-over pilot study.

McKay DL, Chen CY, Yeum KJ, Matthan NR, Lichtenstein AH, Blumberg JB.

Nutr J. 2010 May 12;9:21. doi: 10.1186/1475-2891-9-21.

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