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Items: 1 to 20 of 130

1.

Ternary resin-bound Dynamic Combinatorial Chemistry.

Gromova AV, Ciszewski JM, Miller BL.

Chem Commun (Camb). 2012 Feb 18;48(15):2131-3. doi: 10.1039/c2cc17192a. Epub 2012 Jan 13. Review.

2.

Expanding the medicinally relevant chemical space with compound libraries.

López-Vallejo F, Giulianotti MA, Houghten RA, Medina-Franco JL.

Drug Discov Today. 2012 Jul;17(13-14):718-26. doi: 10.1016/j.drudis.2012.04.001. Epub 2012 Apr 10. Review.

PMID:
22515962
3.

Dynamic selection of novel vancomycin N-terminal derivatives by resin-bound reversed D-Ala-D-Ala.

Chen YY, He WY, Wu Y, Niu CQ, Liu G.

J Comb Chem. 2008 Nov-Dec;10(6):914-22. doi: 10.1021/cc800104b. Epub 2008 Sep 23.

PMID:
18808189
4.

The impact of combinatorial methodologies on medicinal chemistry.

Sanchez-Martin RM, Mittoo S, Bradley M.

Curr Top Med Chem. 2004;4(7):653-69. Review.

PMID:
15032680
5.

[Application of efficient synthetic techniques in drug research].

Zhou Y, Zhang L, Li Z, Liu H.

Yao Xue Xue Bao. 2013 Jul;48(7):1014-30. Review. Chinese.

PMID:
24133968
6.

Combinatorial library design from reagent pharmacophore fingerprints.

Chen H, Engkvist O, Blomberg N.

Methods Mol Biol. 2011;685:135-52. doi: 10.1007/978-1-60761-931-4_7.

PMID:
20981522
7.

A scalable approach to combinatorial library design.

Sharma P, Salapaka S, Beck C.

Methods Mol Biol. 2011;685:71-89. doi: 10.1007/978-1-60761-931-4_4.

PMID:
20981519
8.

Integrating virtual screening and combinatorial chemistry for accelerated drug discovery.

López-Vallejo F, Caulfield T, Martínez-Mayorga K, Giulianotti MA, Nefzi A, Houghten RA, Medina-Franco JL.

Comb Chem High Throughput Screen. 2011 Jul;14(6):475-87. Review.

PMID:
21521151
9.

Liquid-phase combinatorial library synthesis: recent advances and future perspectives.

Barot KP, Nikolova S, Ivanov I, Ghate MD.

Comb Chem High Throughput Screen. 2014;17(5):417-38. Review.

PMID:
24237348
10.

Parallel chemistry in the 21st century.

Long A.

Curr Protoc Pharmacol. 2012 Sep;Chapter 9:Unit9.16. doi: 10.1002/0471141755.ph0916s58.

PMID:
22948852
11.

Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods.

Houghten RA, Pinilla C, Giulianotti MA, Appel JR, Dooley CT, Nefzi A, Ostresh JM, Yu Y, Maggiora GM, Medina-Franco JL, Brunner D, Schneider J.

J Comb Chem. 2008 Jan-Feb;10(1):3-19. Epub 2007 Dec 8. No abstract available.

PMID:
18067268
12.

Scaffold-directed and traceless synthesis of tricyclic quinoxalinone imidazoles under microwave irradiation: for SCS-09 special issue-combinatorial approaches to drug discovery.

Thummanagoti S, Chen CH, Xu ZH, Sun CM.

Mol Divers. 2011 Feb;15(1):101-7. doi: 10.1007/s11030-010-9244-7. Epub 2010 Mar 20.

PMID:
20300840
13.

Combinatorial discovery of fluorescent pharmacophores by multicomponent reactions in droplet arrays.

Burchak ON, Mugherli L, Ostuni M, Lacapère JJ, Balakirev MY.

J Am Chem Soc. 2011 Jul 6;133(26):10058-61. doi: 10.1021/ja204016e. Epub 2011 Jun 14.

PMID:
21644551
14.

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2006.

Dolle RE, Le Bourdonnec B, Goodman AJ, Morales GA, Salvino JM, Zhang W.

J Comb Chem. 2007 Nov-Dec;9(6):855-902. Epub 2007 Sep 19. Review. No abstract available.

PMID:
17877417
15.

Molecular library design using multi-objective optimization methods.

Nicolaou CA, Kannas CC.

Methods Mol Biol. 2011;685:53-69. doi: 10.1007/978-1-60761-931-4_3.

PMID:
20981518
16.

Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity.

Soural M, Bouillon I, Krchnák V.

J Comb Chem. 2008 Nov-Dec;10(6):923-33. doi: 10.1021/cc8001074. Epub 2008 Sep 24.

17.

Customizable Generation of Synthetically Accessible, Local Chemical Subspaces.

Pottel J, Moitessier N.

J Chem Inf Model. 2017 Mar 27;57(3):454-467. doi: 10.1021/acs.jcim.6b00648. Epub 2017 Mar 9.

PMID:
28234470
18.

The discovery of antibacterial agents using diversity-oriented synthesis.

Galloway WR, Bender A, Welch M, Spring DR.

Chem Commun (Camb). 2009 May 14;(18):2446-62. doi: 10.1039/b816852k. Epub 2009 Apr 1. Review.

PMID:
19532856
19.

The design and synthesis of libraries for the discovery of antibacterial and antifungal substances.

Edwards PJ.

Drug Discov Today. 2011 Mar;16(5-6):278-9. doi: 10.1016/j.drudis.2011.01.010. Epub 2011 Jan 28. No abstract available.

PMID:
21277383
20.

Resin-bound dynamic combinatorial chemistry.

McNaughton BR, Miller BL.

Org Lett. 2006 Apr 27;8(9):1803-6.

PMID:
16623555

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