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Items: 1 to 20 of 78

1.

Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons.

Rozenfeld R, Bushlin I, Gomes I, Tzavaras N, Gupta A, Neves S, Battini L, Gusella GL, Lachmann A, Ma'ayan A, Blitzer RD, Devi LA.

PLoS One. 2012;7(1):e29239. doi: 10.1371/journal.pone.0029239. Epub 2012 Jan 3.

2.

Dimerization with cannabinoid receptors allosterically modulates delta opioid receptor activity during neuropathic pain.

Bushlin I, Gupta A, Stockton SD Jr, Miller LK, Devi LA.

PLoS One. 2012;7(12):e49789. doi: 10.1371/journal.pone.0049789. Epub 2012 Dec 14.

3.

AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II.

Rozenfeld R, Gupta A, Gagnidze K, Lim MP, Gomes I, Lee-Ramos D, Nieto N, Devi LA.

EMBO J. 2011 May 3;30(12):2350-63. doi: 10.1038/emboj.2011.139.

4.

Heteromerization of the μ- and δ-opioid receptors produces ligand-biased antagonism and alters μ-receptor trafficking.

Milan-Lobo L, Whistler JL.

J Pharmacol Exp Ther. 2011 Jun;337(3):868-75. doi: 10.1124/jpet.111.179093. Epub 2011 Mar 21.

5.

The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55.

Kargl J, Balenga N, Parzmair GP, Brown AJ, Heinemann A, Waldhoer M.

J Biol Chem. 2012 Dec 28;287(53):44234-48. doi: 10.1074/jbc.M112.364109. Epub 2012 Nov 16.

6.

Anti-analgesic effect of the mu/delta opioid receptor heteromer revealed by ligand-biased antagonism.

Milan-Lobo L, Enquist J, van Rijn RM, Whistler JL.

PLoS One. 2013;8(3):e58362. doi: 10.1371/journal.pone.0058362. Epub 2013 Mar 15.

7.

Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice.

Morgan DJ, Davis BJ, Kearn CS, Marcus D, Cook AJ, Wager-Miller J, Straiker A, Myoga MH, Karduck J, Leishman E, Sim-Selley LJ, Czyzyk TA, Bradshaw HB, Selley DE, Mackie K.

J Neurosci. 2014 Apr 9;34(15):5152-63. doi: 10.1523/JNEUROSCI.3445-12.2014.

8.

Altered gene expression and functional activity of opioid receptors in the cerebellum of CB1 cannabinoid receptor knockout mice after acute treatments with cannabinoids.

Páldyová E, Bereczki E, Sántha M, Wenger T, Borsodi A, Benyhe S.

Acta Biol Hung. 2007;58 Suppl:113-29. doi: 10.1556/ABiol.58.2007.Suppl.9.

PMID:
18297798
9.

Cannabinoid 1 receptor-dependent transactivation of fibroblast growth factor receptor 1 emanates from lipid rafts and amplifies extracellular signal-regulated kinase 1/2 activation in embryonic cortical neurons.

Asimaki O, Leondaritis G, Lois G, Sakellaridis N, Mangoura D.

J Neurochem. 2011 Mar;116(5):866-73. doi: 10.1111/j.1471-4159.2010.07030.x. Epub 2011 Jan 7.

11.

Direct binding of beta-arrestins to two distinct intracellular domains of the delta opioid receptor.

Cen B, Yu Q, Guo J, Wu Y, Ling K, Cheng Z, Ma L, Pei G.

J Neurochem. 2001 Mar;76(6):1887-94.

12.

Biased Type 1 Cannabinoid Receptor Signaling Influences Neuronal Viability in a Cell Culture Model of Huntington Disease.

Laprairie RB, Bagher AM, Kelly ME, Denovan-Wright EM.

Mol Pharmacol. 2016 Mar;89(3):364-75. doi: 10.1124/mol.115.101980. Epub 2015 Dec 23.

13.

Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons.

Berg KA, Rowan MP, Gupta A, Sanchez TA, Silva M, Gomes I, McGuire BA, Portoghese PS, Hargreaves KM, Devi LA, Clarke WP.

Mol Pharmacol. 2012 Feb;81(2):264-72. doi: 10.1124/mol.111.072702. Epub 2011 Nov 9.

14.

mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin.

Lowe JD, Celver JP, Gurevich VV, Chavkin C.

J Biol Chem. 2002 May 3;277(18):15729-35. Epub 2002 Feb 22.

15.

Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation.

Galve-Roperh I, Chiurchiù V, Díaz-Alonso J, Bari M, Guzmán M, Maccarrone M.

Prog Lipid Res. 2013 Oct;52(4):633-50. doi: 10.1016/j.plipres.2013.05.004. Epub 2013 Sep 25. Review.

PMID:
24076098
16.

Co-expression of the human cannabinoid receptor coding region splice variants (hCB₁) affects the function of hCB₁ receptor complexes.

Bagher AM, Laprairie RB, Kelly ME, Denovan-Wright EM.

Eur J Pharmacol. 2013 Dec 5;721(1-3):341-54. doi: 10.1016/j.ejphar.2013.09.002. Epub 2013 Oct 1.

PMID:
24091169
17.

Pharmacological and molecular characterization of a dorsal root ganglion cell line expressing cannabinoid CB(1) and CB(2) receptors.

Fan Y, Hooker BA, Garrison TR, El-Kouhen OF, Idler KB, Holley-Shanks RR, Meyer MD, Yao BB.

Eur J Pharmacol. 2011 Jun 1;659(2-3):161-8. doi: 10.1016/j.ejphar.2011.03.020. Epub 2011 Mar 31.

PMID:
21458448
18.

Mechanism and consequences of delta-opioid receptor internalization.

Eisinger DA, Schulz R.

Crit Rev Neurobiol. 2005;17(1):1-26. Review.

PMID:
16307525
19.
20.

Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation.

Pello OM, Martínez-Muñoz L, Parrillas V, Serrano A, Rodríguez-Frade JM, Toro MJ, Lucas P, Monterrubio M, Martínez-A C, Mellado M.

Eur J Immunol. 2008 Feb;38(2):537-49. doi: 10.1002/eji.200737630.

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