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Items: 1 to 20 of 69


The many roles of PTK7: a versatile regulator of cell-cell communication.

Peradziryi H, Tolwinski NS, Borchers A.

Arch Biochem Biophys. 2012 Aug 1;524(1):71-6. doi: 10.1016/ Epub 2012 Jan 3. Review.


PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.

Peradziryi H, Kaplan NA, Podleschny M, Liu X, Wehner P, Borchers A, Tolwinski NS.

EMBO J. 2011 Jul 19;30(18):3729-40. doi: 10.1038/emboj.2011.236.


Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development.

Hayes M, Naito M, Daulat A, Angers S, Ciruna B.

Development. 2013 Apr;140(8):1807-18. doi: 10.1242/dev.090183. Erratum in: Development. 2013 Apr;140(8):1807.


The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway.

Martinez S, Scerbo P, Giordano M, Daulat AM, Lhoumeau AC, Thomé V, Kodjabachian L, Borg JP.

J Biol Chem. 2015 Dec 18;290(51):30562-72. doi: 10.1074/jbc.M115.697615. Epub 2015 Oct 23.


PTK7 modulates Wnt signaling activity via LRP6.

Bin-Nun N, Lichtig H, Malyarova A, Levy M, Elias S, Frank D.

Development. 2014 Jan;141(2):410-21. doi: 10.1242/dev.095984. Epub 2013 Dec 18.


Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex.

Yamamoto S, Nishimura O, Misaki K, Nishita M, Minami Y, Yonemura S, Tarui H, Sasaki H.

Dev Cell. 2008 Jul;15(1):23-36. doi: 10.1016/j.devcel.2008.05.007.


Leading Wnt down a PCP path: Cthrc1 acts as a coreceptor in the Wnt-PCP pathway.

Kelley MW.

Dev Cell. 2008 Jul;15(1):7-8. doi: 10.1016/j.devcel.2008.06.008.


PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium.

Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X.

Curr Biol. 2012 Jun 5;22(11):956-66. doi: 10.1016/j.cub.2012.03.068. Epub 2012 May 3.


PTK7: a cell polarity receptor with multiple facets.

Lhoumeau AC, Puppo F, Prébet T, Kodjabachian L, Borg JP.

Cell Cycle. 2011 Apr 15;10(8):1233-6. Epub 2011 Apr 15.


The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.

Golubkov VS, Chekanov AV, Cieplak P, Aleshin AE, Chernov AV, Zhu W, Radichev IA, Zhang D, Dong PD, Strongin AY.

J Biol Chem. 2010 Nov 12;285(46):35740-9. doi: 10.1074/jbc.M110.165159. Epub 2010 Sep 13.


PTK7 localization and protein stability is affected by canonical Wnt ligands.

Berger H, Breuer M, Peradziryi H, Podleschny M, Jacob R, Borchers A.

J Cell Sci. 2017 Jun 1;130(11):1890-1903. doi: 10.1242/jcs.198580. Epub 2017 Apr 18.


Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling.

Puppo F, Thomé V, Lhoumeau AC, Cibois M, Gangar A, Lembo F, Belotti E, Marchetto S, Lécine P, Prébet T, Sebbagh M, Shin WS, Lee ST, Kodjabachian L, Borg JP.

EMBO Rep. 2011 Jan;12(1):43-9. doi: 10.1038/embor.2010.185. Epub 2010 Dec 3.


Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation.

Wu LW, Mayo LD, Dunbar JD, Kessler KM, Baerwald MR, Jaffe EA, Wang D, Warren RS, Donner DB.

J Biol Chem. 2000 Feb 18;275(7):5096-103.


PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates.

Lu X, Borchers AG, Jolicoeur C, Rayburn H, Baker JC, Tessier-Lavigne M.

Nature. 2004 Jul 1;430(6995):93-8.


[Regulation of cellular responses by non-canonical Wnt signaling].

Nishita M, Endo M, Minami Y.

Clin Calcium. 2013 Jun;23(6):809-15. doi: CliCa1306809815. Review. Japanese.


PlexinA1 interacts with PTK7 and is required for neural crest migration.

Wagner G, Peradziryi H, Wehner P, Borchers A.

Biochem Biophys Res Commun. 2010 Nov 12;402(2):402-7. doi: 10.1016/j.bbrc.2010.10.044. Epub 2010 Oct 12.


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