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Items: 1 to 20 of 129

1.

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter.

Hirota JA, Hirota SA, Warner SM, Stefanowicz D, Shaheen F, Beck PL, Macdonald JA, Hackett TL, Sin DD, Van Eeden S, Knight DA.

J Allergy Clin Immunol. 2012 Apr;129(4):1116-25.e6. doi: 10.1016/j.jaci.2011.11.033. Epub 2012 Jan 9.

PMID:
22227418
2.

The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.

Hirota JA, Gold MJ, Hiebert PR, Parkinson LG, Wee T, Smith D, Hansbro PM, Carlsten C, VanEeden S, Sin DD, McNagny KM, Knight DA.

Am J Respir Cell Mol Biol. 2015 Jan;52(1):96-105. doi: 10.1165/rcmb.2014-0158OC.

PMID:
24988285
3.

Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.

Ather JL, Ckless K, Martin R, Foley KL, Suratt BT, Boyson JE, Fitzgerald KA, Flavell RA, Eisenbarth SC, Poynter ME.

J Immunol. 2011 Jul 1;187(1):64-73. doi: 10.4049/jimmunol.1100500. Epub 2011 May 27.

4.

The nucleotide-binding domain and leucine-rich repeat protein-3 inflammasome is not activated in airway smooth muscle upon toll-like receptor-2 ligation.

Hirota JA, Im H, Rahman MM, Rumzhum NN, Manetsch M, Pascoe CD, Bunge K, Alkhouri H, Oliver BG, Ammit AJ.

Am J Respir Cell Mol Biol. 2013 Oct;49(4):517-24. doi: 10.1165/rcmb.2013-0047OC.

PMID:
23614732
5.

Hyaluronan activation of the Nlrp3 inflammasome contributes to the development of airway hyperresponsiveness.

Feng F, Li Z, Potts-Kant EN, Wu Y, Foster WM, Williams KL, Hollingsworth JW.

Environ Health Perspect. 2012 Dec;120(12):1692-8. doi: 10.1289/ehp.1205188. Epub 2012 Sep 24. Retraction in: Environ Health Perspect. 2015 Jul;123(7):A172.

6.

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.

Zheng Q, Ren Y, Reinach PS, She Y, Xiao B, Hua S, Qu J, Chen W.

Exp Eye Res. 2014 Aug;125:1-8. doi: 10.1016/j.exer.2014.05.001. Epub 2014 May 14.

PMID:
24836981
7.

Urban particulate matter increases human airway epithelial cell IL-1β secretion following scratch wounding and H1N1 influenza A exposure in vitro.

Hirota JA, Marchant DJ, Singhera GK, Moheimani F, Dorscheid DR, Carlsten C, Sin D, Knight D.

Exp Lung Res. 2015;41(6):353-62. doi: 10.3109/01902148.2015.1040528. Epub 2015 Jul 7.

PMID:
26151556
8.

The NLRP3/ASC inflammasome promotes T-cell-dependent immune complex glomerulonephritis by canonical and noncanonical mechanisms.

Andersen K, Eltrich N, Lichtnekert J, Anders HJ, Vielhauer V.

Kidney Int. 2014 Nov;86(5):965-78. doi: 10.1038/ki.2014.161. Epub 2014 May 7.

PMID:
24805106
9.

G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3.

Giguère PM, Gall BJ, Ezekwe EA Jr, Laroche G, Buckley BK, Kebaier C, Wilson JE, Ting JP, Siderovski DP, Duncan JA.

J Biol Chem. 2014 Nov 28;289(48):33245-57. doi: 10.1074/jbc.M114.578393. Epub 2014 Sep 30.

10.

TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo.

He Y, Franchi L, Núñez G.

J Immunol. 2013 Jan 1;190(1):334-9. doi: 10.4049/jimmunol.1202737. Epub 2012 Dec 7.

12.

Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans.

Ganesan S, Rathinam VA, Bossaller L, Army K, Kaiser WJ, Mocarski ES, Dillon CP, Green DR, Mayadas TN, Levitz SM, Hise AG, Silverman N, Fitzgerald KA.

J Immunol. 2014 Sep 1;193(5):2519-30. doi: 10.4049/jimmunol.1400276. Epub 2014 Jul 25.

13.

The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation.

Solini A, Menini S, Rossi C, Ricci C, Santini E, Blasetti Fantauzzi C, Iacobini C, Pugliese G.

J Pathol. 2013 Nov;231(3):342-53. doi: 10.1002/path.4237. Epub 2013 Sep 3.

PMID:
23843215
14.

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A.

Cardiovasc Res. 2013 Jul 1;99(1):164-74. doi: 10.1093/cvr/cvt091. Epub 2013 Apr 10.

PMID:
23580606
15.

The NLRP3 inflammasome: role in airway inflammation.

Im H, Ammit AJ.

Clin Exp Allergy. 2014 Feb;44(2):160-72. doi: 10.1111/cea.12206. Review.

PMID:
24118105
16.

Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release.

Laudisi F, Spreafico R, Evrard M, Hughes TR, Mandriani B, Kandasamy M, Morgan BP, Sivasankar B, Mortellaro A.

J Immunol. 2013 Aug 1;191(3):1006-10. doi: 10.4049/jimmunol.1300489. Epub 2013 Jul 1.

17.

Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients.

Zheng Q, Ren Y, Reinach PS, Xiao B, Lu H, Zhu Y, Qu J, Chen W.

Exp Eye Res. 2015 May;134:133-40. doi: 10.1016/j.exer.2015.02.013. Epub 2015 Feb 18.

PMID:
25701684
18.

Elevated expression of the NLRP3 inflammasome in neutrophilic asthma.

Simpson JL, Phipps S, Baines KJ, Oreo KM, Gunawardhana L, Gibson PG.

Eur Respir J. 2014 Apr;43(4):1067-76. doi: 10.1183/09031936.00105013. Epub 2013 Oct 17.

19.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

20.

Functional relevance of NLRP3 inflammasome-mediated interleukin (IL)-1β during acute allergic airway inflammation.

Ritter M, Straubinger K, Schmidt S, Busch DH, Hagner S, Garn H, Prazeres da Costa C, Layland LE.

Clin Exp Immunol. 2014 Nov;178(2):212-23. doi: 10.1111/cei.12400.

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