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Selective expansion of polyfunctional pathogen-specific CD4(+) T cells in HIV-1-infected patients with immune reconstitution inflammatory syndrome.

Mahnke YD, Greenwald JH, DerSimonian R, Roby G, Antonelli LR, Sher A, Roederer M, Sereti I.

Blood. 2012 Mar 29;119(13):3105-12. doi: 10.1182/blood-2011-09-380840. Epub 2012 Jan 4.


Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4+ T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome.

Ravimohan S, Tamuhla N, Nfanyana K, Steenhoff AP, Letlhogile R, Frank I, MacGregor RR, Gross R, Weissman D, Bisson GP.

Clin Infect Dis. 2016 Mar 15;62(6):795-803. doi: 10.1093/cid/civ978. Epub 2015 Nov 26.


Skewing of the CD4(+) T-cell pool toward monofunctional antigen-specific responses in patients with immune reconstitution inflammatory syndrome in The Gambia.

Wilson H, de Jong BC, Peterson K, Jaye A, Kampmann B, Ota MO, Sutherland JS.

Clin Infect Dis. 2013 Aug;57(4):594-603. doi: 10.1093/cid/cit285. Epub 2013 May 3.


Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome.

Antonelli LR, Mahnke Y, Hodge JN, Porter BO, Barber DL, DerSimonian R, Greenwald JH, Roby G, Mican J, Sher A, Roederer M, Sereti I.

Blood. 2010 Nov 11;116(19):3818-27. doi: 10.1182/blood-2010-05-285080. Epub 2010 Jul 26.


IRIS: the unfortunate rainbow of HIV.

Chahroudi A, Silvestri G.

Blood. 2012 Mar 29;119(13):2971-2. doi: 10.1182/blood-2012-01-403683.


Toxoplasmosis-associated IRIS involving the CNS: a case report with longitudinal analysis of T cell subsets.

Rb-Silva R, Nobrega C, Reiriz E, Almeida S, Sarmento-Castro R, Correia-Neves M, Horta A.

BMC Infect Dis. 2017 Jan 13;17(1):66. doi: 10.1186/s12879-016-2159-x.


Lower Pre-Treatment T Cell Activation in Early- and Late-Onset Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome.

Goovaerts O, Jennes W, Massinga-Loembé M, Ondoa P, Ceulemans A, Vereecken C, Worodria W, Mayanja-Kizza H, Colebunders R, Kestens L; TB-IRIS Study Group.

PLoS One. 2015 Jul 24;10(7):e0133924. doi: 10.1371/journal.pone.0133924. eCollection 2015.


TB-IRIS after initiation of antiretroviral therapy is associated with expansion of preexistent Th1 responses against Mycobacterium tuberculosis antigens.

Vignesh R, Kumarasamy N, Lim A, Solomon S, Murugavel KG, Balakrishnan P, Solomon SS, Mayer KH, Swathirajan CR, Chandrasekaran E, Pradeep A, Poongulali S, Benson CA, French MA.

J Acquir Immune Defic Syndr. 2013 Nov 1;64(3):241-8. doi: 10.1097/QAI.0b013e31829f6df2. Erratum in: J Acquir Immune Defic Syndr. 2014 Sep 1;67(1):e44.


Type 1 helper T cells and FoxP3-positive T cells in HIV-tuberculosis-associated immune reconstitution inflammatory syndrome.

Meintjes G, Wilkinson KA, Rangaka MX, Skolimowska K, van Veen K, Abrahams M, Seldon R, Pepper DJ, Rebe K, Mouton P, van Cutsem G, Nicol MP, Maartens G, Wilkinson RJ.

Am J Respir Crit Care Med. 2008 Nov 15;178(10):1083-9. doi: 10.1164/rccm.200806-858OC. Epub 2008 Aug 28.


The immunopathogenesis of the HIV tuberculosis immune reconstitution inflammatory syndrome.

Lai RP, Nakiwala JK, Meintjes G, Wilkinson RJ.

Eur J Immunol. 2013 Aug;43(8):1995-2002. doi: 10.1002/eji.201343632. Review.


Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases.

Giacoia-Gripp CB, Sales AM, Nery JA, Santos-Oliveira JR, de Oliveira AL, Sarno EN, Morgado MG.

PLoS One. 2011;6(12):e28735. doi: 10.1371/journal.pone.0028735. Epub 2011 Dec 21.


Pathogenesis of the immune reconstitution inflammatory syndrome in HIV-infected patients.

Martin-Blondel G, Mars LT, Liblau RS.

Curr Opin Infect Dis. 2012 Jun;25(3):312-20. doi: 10.1097/QCO.0b013e328352b664. Review.


Immune reconstitution inflammatory syndrome among HIV-infected South African infants initiating antiretroviral therapy.

Smith K, Kuhn L, Coovadia A, Meyers T, Hu CC, Reitz C, Barry G, Strehlau R, Sherman G, Abrams EJ.

AIDS. 2009 Jun 1;23(9):1097-107. doi: 10.1097/QAD.0b013e32832afefc.


Immunological profiles of immune restoration disease presenting as mycobacterial lymphadenitis and cryptococcal meningitis.

Tan DB, Yong YK, Tan HY, Kamarulzaman A, Tan LH, Lim A, James I, French M, Price P.

HIV Med. 2008 May;9(5):307-16. doi: 10.1111/j.1468-1293.2008.00565.x.


HIV-1-infected children on HAART: immunologic features of three different levels of viral suppression.

Zaccarelli-Filho CA, Ono E, Machado DM, Brunialti M, Succi RC, Salomão R, Kallás EG, de Moraes-Pinto MI.

Cytometry B Clin Cytom. 2007 Jan 15;72(1):14-21.


The clinical pattern, prevalence, and factors associated with immune reconstitution inflammatory syndrome in Ugandan children.

Orikiiriza J, Bakeera-Kitaka S, Musiime V, Mworozi EA, Mugyenyi P, Boulware DR.

AIDS. 2010 Aug 24;24(13):2009-17. doi: 10.1097/QAD.0b013e32833b260a.


HIV & immune reconstitution inflammatory syndrome (IRIS).

Sharma SK, Soneja M.

Indian J Med Res. 2011 Dec;134(6):866-77. doi: 10.4103/0971-5916.92632. Review.


In Vivo Molecular Dissection of the Effects of HIV-1 in Active Tuberculosis.

Bell LC, Pollara G, Pascoe M, Tomlinson GS, Lehloenya RJ, Roe J, Meldau R, Miller RF, Ramsay A, Chain BM, Dheda K, Noursadeghi M.

PLoS Pathog. 2016 Mar 17;12(3):e1005469. doi: 10.1371/journal.ppat.1005469. eCollection 2016 Mar.


Chemokine levels and chemokine receptor expression in the blood and the cerebrospinal fluid of HIV-infected patients with cryptococcal meningitis and cryptococcosis-associated immune reconstitution inflammatory syndrome.

Chang CC, Omarjee S, Lim A, Spelman T, Gosnell BI, Carr WH, Elliott JH, Moosa MY, Ndung'u T, French MA, Lewin SR.

J Infect Dis. 2013 Nov 15;208(10):1604-12. doi: 10.1093/infdis/jit388. Epub 2013 Aug 1.

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