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Items: 1 to 20 of 105

1.

Autophagic degradation of tau in primary neurons and its enhancement by trehalose.

Krüger U, Wang Y, Kumar S, Mandelkow EM.

Neurobiol Aging. 2012 Oct;33(10):2291-305. doi: 10.1016/j.neurobiolaging.2011.11.009. Epub 2011 Dec 14.

PMID:
22169203
2.

Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy.

Schaeffer V, Lavenir I, Ozcelik S, Tolnay M, Winkler DT, Goedert M.

Brain. 2012 Jul;135(Pt 7):2169-77. doi: 10.1093/brain/aws143. Epub 2012 Jun 10.

3.

Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons.

Padmanabhan J, Levy M, Dickson DW, Potter H.

Brain. 2006 Nov;129(Pt 11):3020-34. Epub 2006 Sep 20.

PMID:
16987932
4.

Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation.

Rodríguez-Navarro JA, Rodríguez L, Casarejos MJ, Solano RM, Gómez A, Perucho J, Cuervo AM, García de Yébenes J, Mena MA.

Neurobiol Dis. 2010 Sep;39(3):423-38. doi: 10.1016/j.nbd.2010.05.014. Epub 2010 May 28.

PMID:
20546895
5.

BAG3 facilitates the clearance of endogenous tau in primary neurons.

Lei Z, Brizzee C, Johnson GV.

Neurobiol Aging. 2015 Jan;36(1):241-8. doi: 10.1016/j.neurobiolaging.2014.08.012. Epub 2014 Aug 16.

6.

Amyloid beta peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures.

Zheng WH, Bastianetto S, Mennicken F, Ma W, Kar S.

Neuroscience. 2002;115(1):201-11.

PMID:
12401334
7.

Memantine protects rat cortical cultured neurons against beta-amyloid-induced toxicity by attenuating tau phosphorylation.

Song MS, Rauw G, Baker GB, Kar S.

Eur J Neurosci. 2008 Nov;28(10):1989-2002. doi: 10.1111/j.1460-9568.2008.06498.x.

PMID:
19046381
8.

Roles of AMP-activated protein kinase in Alzheimer's disease.

Cai Z, Yan LJ, Li K, Quazi SH, Zhao B.

Neuromolecular Med. 2012 Mar;14(1):1-14. doi: 10.1007/s12017-012-8173-2. Epub 2012 Feb 26. Review.

PMID:
22367557
9.

Novel drugs affecting tau behavior in the treatment of Alzheimer's disease and tauopathies.

Navarrete LP, Pérez P, Morales I, Maccioni RB.

Curr Alzheimer Res. 2011 Sep;8(6):678-85. Review.

PMID:
21605038
10.

Glutamate but not interleukin-6 influences the phosphorylation of tau in primary rat hippocampal neurons.

Hüll M, Eistetter J, Fiebich BL, Bauer J.

Neurosci Lett. 1999 Feb 12;261(1-2):33-6.

PMID:
10081920
11.

Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease.

Fath T, Eidenmüller J, Brandt R.

J Neurosci. 2002 Nov 15;22(22):9733-41.

12.

A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration.

Amadoro G, Corsetti V, Stringaro A, Colone M, D'Aguanno S, Meli G, Ciotti M, Sancesario G, Cattaneo A, Bussani R, Mercanti D, Calissano P.

J Alzheimers Dis. 2010;21(2):445-70. doi: 10.3233/JAD-2010-100120.

PMID:
20571215
13.

Synergy and antagonism of macroautophagy and chaperone-mediated autophagy in a cell model of pathological tau aggregation.

Wang Y, Martinez-Vicente M, Krüger U, Kaushik S, Wong E, Mandelkow EM, Cuervo AM, Mandelkow E.

Autophagy. 2010 Jan;6(1):182-3. Epub 2010 Jan 1. Review.

PMID:
20023429
14.

JNK plays a key role in tau hyperphosphorylation in Alzheimer's disease models.

Ploia C, Antoniou X, Sclip A, Grande V, Cardinetti D, Colombo A, Canu N, Benussi L, Ghidoni R, Forloni G, Borsello T.

J Alzheimers Dis. 2011;26(2):315-29. doi: 10.3233/JAD-2011-110320.

PMID:
21628793
15.

NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation.

Amadoro G, Ciotti MT, Costanzi M, Cestari V, Calissano P, Canu N.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2892-7. Epub 2006 Feb 13.

16.

The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease.

Liu Z, Li T, Li P, Wei N, Zhao Z, Liang H, Ji X, Chen W, Xue M, Wei J.

Oxid Med Cell Longev. 2015;2015:352723. doi: 10.1155/2015/352723. Epub 2015 Jun 15. Review.

17.

NPAS4 Facilitates the Autophagic Clearance of Endogenous Tau in Rat Cortical Neurons.

Fan W, Long Y, Lai Y, Wang X, Chen G, Zhu B.

J Mol Neurosci. 2016 Apr;58(4):401-10. doi: 10.1007/s12031-015-0692-5. Epub 2015 Dec 3.

PMID:
26635026
18.
19.

Expression of a truncated tau protein induces oxidative stress in a rodent model of tauopathy.

Cente M, Filipcik P, Pevalova M, Novak M.

Eur J Neurosci. 2006 Aug;24(4):1085-90.

PMID:
16930434
20.

HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology.

Sepulveda-Diaz JE, Alavi Naini SM, Huynh MB, Ouidja MO, Yanicostas C, Chantepie S, Villares J, Lamari F, Jospin E, van Kuppevelt TH, Mensah-Nyagan AG, Raisman-Vozari R, Soussi-Yanicostas N, Papy-Garcia D.

Brain. 2015 May;138(Pt 5):1339-54. doi: 10.1093/brain/awv056. Epub 2015 Apr 4.

PMID:
25842390

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