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Items: 1 to 20 of 129

1.

Integration of Elf-4 into stem/progenitor and erythroid regulatory networks through locus-wide chromatin studies coupled with in vivo functional validation.

Smith AM, Calero-Nieto FJ, Schütte J, Kinston S, Timms RT, Wilson NK, Hannah RL, Landry JR, Göttgens B.

Mol Cell Biol. 2012 Feb;32(4):763-73. doi: 10.1128/MCB.05745-11. Epub 2011 Dec 12.

2.

Transcriptional regulation of Elf-1: locus-wide analysis reveals four distinct promoters, a tissue-specific enhancer, control by PU.1 and the importance of Elf-1 downregulation for erythroid maturation.

Calero-Nieto FJ, Wood AD, Wilson NK, Kinston S, Landry JR, Göttgens B.

Nucleic Acids Res. 2010 Oct;38(19):6363-74. doi: 10.1093/nar/gkq490. Epub 2010 Jun 4.

3.

The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1.

Göttgens B, Broccardo C, Sanchez MJ, Deveaux S, Murphy G, Göthert JR, Kotsopoulou E, Kinston S, Delaney L, Piltz S, Barton LM, Knezevic K, Erber WN, Begley CG, Frampton J, Green AR.

Mol Cell Biol. 2004 Mar;24(5):1870-83.

4.

Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells.

Wilson NK, Timms RT, Kinston SJ, Cheng YH, Oram SH, Landry JR, Mullender J, Ottersbach K, Gottgens B.

Mol Cell Biol. 2010 Aug;30(15):3853-63. doi: 10.1128/MCB.00032-10. Epub 2010 Jun 1.

5.

Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny.

Migueles RP, Shaw L, Rodrigues NP, May G, Henseleit K, Anderson KG, Goker H, Jones CM, de Bruijn MF, Brickman JM, Enver T.

Dev Biol. 2017 Apr 15;424(2):236-245. doi: 10.1016/j.ydbio.2016.12.021. Epub 2017 Feb 9.

PMID:
28189604
6.

Fli1, Elf1, and Ets1 regulate the proximal promoter of the LMO2 gene in endothelial cells.

Landry JR, Kinston S, Knezevic K, Donaldson IJ, Green AR, Göttgens B.

Blood. 2005 Oct 15;106(8):2680-7. Epub 2005 Jun 30.

7.

Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors.

Landry JR, Bonadies N, Kinston S, Knezevic K, Wilson NK, Oram SH, Janes M, Piltz S, Hammett M, Carter J, Hamilton T, Donaldson IJ, Lacaud G, Frampton J, Follows G, Kouskoff V, Göttgens B.

Blood. 2009 Jun 4;113(23):5783-92. doi: 10.1182/blood-2008-11-187757. Epub 2009 Jan 26.

8.

Molecular heterogeneity of regulatory elements of the mouse GATA-1 gene.

Ronchi A, Cirò M, Cairns L, Basilico L, Corbella P, Ricciardi-Castagnoli P, Cross M, Ghysdael J, Ottolenghi S.

Genes Funct. 1997 Nov;1(4):245-58.

PMID:
9678901
9.

A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene.

Nishimura S, Takahashi S, Kuroha T, Suwabe N, Nagasawa T, Trainor C, Yamamoto M.

Mol Cell Biol. 2000 Jan;20(2):713-23.

10.

Genomic footprinting and sequencing of human beta-globin locus. Tissue specificity and cell line artifact.

Reddy PM, Stamatoyannopoulos G, Papayannopoulou T, Shen CK.

J Biol Chem. 1994 Mar 18;269(11):8287-95.

11.

The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis.

Hoogenkamp M, Krysinska H, Ingram R, Huang G, Barlow R, Clarke D, Ebralidze A, Zhang P, Tagoh H, Cockerill PN, Tenen DG, Bonifer C.

Mol Cell Biol. 2007 Nov;27(21):7425-38. Epub 2007 Sep 4.

12.

The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.

Wilson NK, Miranda-Saavedra D, Kinston S, Bonadies N, Foster SD, Calero-Nieto F, Dawson MA, Donaldson IJ, Dumon S, Frampton J, Janky R, Sun XH, Teichmann SA, Bannister AJ, Göttgens B.

Blood. 2009 May 28;113(22):5456-65. doi: 10.1182/blood-2009-01-200048. Epub 2009 Apr 3.

13.

A compendium of genome-wide hematopoietic transcription factor maps supports the identification of gene regulatory control mechanisms.

Hannah R, Joshi A, Wilson NK, Kinston S, Göttgens B.

Exp Hematol. 2011 May;39(5):531-41. doi: 10.1016/j.exphem.2011.02.009. Epub 2011 Feb 19.

PMID:
21338655
14.

Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis.

Cooney JD, Hildick-Smith GJ, Shafizadeh E, McBride PF, Carroll KJ, Anderson H, Shaw GC, Tamplin OJ, Branco DS, Dalton AJ, Shah DI, Wong C, Gallagher PG, Zon LI, North TE, Paw BH.

Dev Biol. 2013 Jan 15;373(2):431-41. doi: 10.1016/j.ydbio.2012.08.015. Epub 2012 Aug 29.

15.

GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling.

Grass JA, Boyer ME, Pal S, Wu J, Weiss MJ, Bresnick EH.

Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8811-6. Epub 2003 Jul 11.

16.

A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients.

Oram SH, Thoms JA, Pridans C, Janes ME, Kinston SJ, Anand S, Landry JR, Lock RB, Jayaraman PS, Huntly BJ, Pimanda JE, Göttgens B.

Oncogene. 2010 Oct 28;29(43):5796-808. doi: 10.1038/onc.2010.320. Epub 2010 Aug 2.

PMID:
20676125
17.

Multiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific manner.

O'Reilly D, Quinn CM, El-Shanawany T, Gordon S, Greaves DR.

J Biol Chem. 2003 Jun 13;278(24):21909-19. Epub 2003 Apr 3.

18.

CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells.

Steiner LA, Schulz V, Makismova Y, Lezon-Geyda K, Gallagher PG.

PLoS One. 2016 May 24;11(5):e0155378. doi: 10.1371/journal.pone.0155378. eCollection 2016.

19.

Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites.

Hogart A, Lichtenberg J, Ajay SS, Anderson S; NIH Intramural Sequencing Center, Margulies EH, Bodine DM.

Genome Res. 2012 Aug;22(8):1407-18. doi: 10.1101/gr.132878.111. Epub 2012 Jun 8.

20.

Elf-1 contributes to the function of the complex interleukin (IL)-2-responsive enhancer in the mouse IL-2 receptor alpha gene.

Serdobova I, Pla M, Reichenbach P, Sperisen P, Ghysdael J, Wilson A, Freeman J, Nabholz M.

J Exp Med. 1997 Apr 7;185(7):1211-21.

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