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Items: 1 to 20 of 143

1.

Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas.

Kopinke D, Brailsford M, Pan FC, Magnuson MA, Wright CV, Murtaugh LC.

Dev Biol. 2012 Feb 1;362(1):57-64. doi: 10.1016/j.ydbio.2011.11.010. Epub 2011 Nov 29.

2.

Impact of Sox9 dosage and Hes1-mediated Notch signaling in controlling the plasticity of adult pancreatic duct cells in mice.

Hosokawa S, Furuyama K, Horiguchi M, Aoyama Y, Tsuboi K, Sakikubo M, Goto T, Hirata K, Tanabe W, Nakano Y, Akiyama H, Kageyama R, Uemoto S, Kawaguchi Y.

Sci Rep. 2015 Feb 17;5:8518. doi: 10.1038/srep08518.

3.

Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.

Fukuda A, Kawaguchi Y, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Koizumi M, Boyer DF, Fujimoto K, Doi R, Kageyama R, Wright CV, Chiba T.

J Clin Invest. 2006 Jun;116(6):1484-93. Epub 2006 May 18.

4.

Expression of the Notch signaling pathway and effect on exocrine cell proliferation in adult rat pancreas.

Rooman I, De Medts N, Baeyens L, Lardon J, De Breuck S, Heimberg H, Bouwens L.

Am J Pathol. 2006 Oct;169(4):1206-14.

5.

Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas.

Kopinke D, Brailsford M, Shea JE, Leavitt R, Scaife CL, Murtaugh LC.

Development. 2011 Feb;138(3):431-41. doi: 10.1242/dev.053843.

6.

Notch/Rbpjκ signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons.

Aujla PK, Naratadam GT, Xu L, Raetzman LT.

Development. 2013 Sep;140(17):3511-21. doi: 10.1242/dev.098681. Epub 2013 Jul 24.

7.

RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.

Dong Y, Jesse AM, Kohn A, Gunnell LM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ.

Development. 2010 May;137(9):1461-71. doi: 10.1242/dev.042911. Epub 2010 Mar 24.

8.

ATF2 maintains a subset of neural progenitors through CBF1/Notch independent Hes-1 expression and synergistically activates the expression of Hes-1 in Notch-dependent neural progenitors.

Sanalkumar R, Indulekha CL, Divya TS, Divya MS, Anto RJ, Vinod B, Vidyanand S, Jagatha B, Venugopal S, James J.

J Neurochem. 2010 May;113(4):807-18. doi: 10.1111/j.1471-4159.2010.06574.x. Epub 2010 Jan 8.

9.

Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment.

Qu X, Afelik S, Jensen JN, Bukys MA, Kobberup S, Schmerr M, Xiao F, Nyeng P, Veronica Albertoni M, Grapin-Botton A, Jensen J.

Dev Biol. 2013 Apr 1;376(1):1-12. doi: 10.1016/j.ydbio.2013.01.021. Epub 2013 Jan 29.

10.

Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling.

Guiu J, Shimizu R, D'Altri T, Fraser ST, Hatakeyama J, Bresnick EH, Kageyama R, Dzierzak E, Yamamoto M, Espinosa L, Bigas A.

J Exp Med. 2013 Jan 14;210(1):71-84. doi: 10.1084/jem.20120993. Epub 2012 Dec 24.

11.

Conditional ablation of Notch signaling in pancreatic development.

Nakhai H, Siveke JT, Klein B, Mendoza-Torres L, Mazur PK, Algül H, Radtke F, Strobl L, Zimber-Strobl U, Schmid RM.

Development. 2008 Aug;135(16):2757-65. doi: 10.1242/dev.013722. Epub 2008 Jul 17.

12.

Rbp-j regulates expansion of pancreatic epithelial cells and their differentiation into exocrine cells during mouse development.

Fujikura J, Hosoda K, Kawaguchi Y, Noguchi M, Iwakura H, Odori S, Mori E, Tomita T, Hirata M, Ebihara K, Masuzaki H, Fukuda A, Furuyama K, Tanigaki K, Yabe D, Nakao K.

Dev Dyn. 2007 Oct;236(10):2779-91.

13.

Antagonistic regulation of p57kip2 by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest.

Zalc A, Hayashi S, Auradé F, Bröhl D, Chang T, Mademtzoglou D, Mourikis P, Yao Z, Cao Y, Birchmeier C, Relaix F.

Development. 2014 Jul;141(14):2780-90. doi: 10.1242/dev.110155.

14.

Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms.

Ou-Yang HF, Zhang HW, Wu CG, Zhang P, Zhang J, Li JC, Hou LH, He F, Ti XY, Song LQ, Zhang SZ, Feng L, Qi HW, Han H.

Mol Cell Biochem. 2009 Jan;320(1-2):109-14. doi: 10.1007/s11010-008-9912-4. Epub 2008 Sep 6.

PMID:
18777163
15.

Hes1 Controls Exocrine Cell Plasticity and Restricts Development of Pancreatic Ductal Adenocarcinoma in a Mouse Model.

Hidalgo-Sastre A, Brodylo RL, Lubeseder-Martellato C, Sipos B, Steiger K, Lee M, von Figura G, Grünwald B, Zhong S, Trajkovic-Arsic M, Neff F, Schmid RM, Siveke JT.

Am J Pathol. 2016 Nov;186(11):2934-2944. doi: 10.1016/j.ajpath.2016.07.025. Epub 2016 Sep 14.

PMID:
27639167
16.

Multiple roles of Notch signaling in the regulation of epidermal development.

Moriyama M, Durham AD, Moriyama H, Hasegawa K, Nishikawa S, Radtke F, Osawa M.

Dev Cell. 2008 Apr;14(4):594-604. doi: 10.1016/j.devcel.2008.01.017.

17.

Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity.

Wall DS, Mears AJ, McNeill B, Mazerolle C, Thurig S, Wang Y, Kageyama R, Wallace VA.

J Cell Biol. 2009 Jan 12;184(1):101-12. doi: 10.1083/jcb.200805155. Epub 2009 Jan 5.

18.

Notch-Rbpj signaling is required for the development of noradrenergic neurons in the mouse locus coeruleus.

Shi M, Hu ZL, Zheng MH, Song NN, Huang Y, Zhao G, Han H, Ding YQ.

J Cell Sci. 2012 Sep 15;125(Pt 18):4320-32. doi: 10.1242/jcs.102152. Epub 2012 Jun 20.

19.
20.

Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression.

Kim TH, Shivdasani RA.

J Biol Chem. 2011 Apr 1;286(13):11427-33. doi: 10.1074/jbc.M110.188797. Epub 2011 Jan 31.

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