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Items: 1 to 20 of 116

1.

Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy.

Li Z, Garner AL, Gloeckner C, Janda KD, Carlow CK.

PLoS Negl Trop Dis. 2011 Nov;5(11):e1411. doi: 10.1371/journal.pntd.0001411. Epub 2011 Nov 29.

2.

Filamentation temperature-sensitive protein Z (FtsZ) of Wolbachia, endosymbiont of Wuchereria bancrofti: a potential target for anti-filarial chemotherapy.

Sharma R, Hoti SL, Vasuki V, Sankari T, Meena RL, Das PK.

Acta Trop. 2013 Mar;125(3):330-8. doi: 10.1016/j.actatropica.2012.12.004. Epub 2012 Dec 19.

PMID:
23262214
3.

The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target.

Wu B, Novelli J, Foster J, Vaisvila R, Conway L, Ingram J, Ganatra M, Rao AU, Hamza I, Slatko B.

PLoS Negl Trop Dis. 2009 Jul 14;3(7):e475. doi: 10.1371/journal.pntd.0000475.

4.

Homology modeling of NAD+-dependent DNA ligase of the Wolbachia endosymbiont of Brugia malayi and its drug target potential using dispiro-cycloalkanones.

Shrivastava N, Nag JK, Pandey J, Tripathi RP, Shah P, Siddiqi MI, Misra-Bhattacharya S.

Antimicrob Agents Chemother. 2015 Jul;59(7):3736-47. doi: 10.1128/AAC.03449-14. Epub 2015 Apr 6.

5.

Cloning, expression and characterization of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) from Wolbachia endosymbiont of human lymphatic filarial parasite Brugia malayi.

Shahab M, Verma M, Pathak M, Mitra K, Misra-Bhattacharya S.

PLoS One. 2014 Jun 18;9(6):e99884. doi: 10.1371/journal.pone.0099884. eCollection 2014.

6.
7.

Sequencing and analysis of a 63 kb bacterial artificial chromosome insert from the Wolbachia endosymbiont of the human filarial parasite Brugia malayi.

Ware J, Moran L, Foster J, Posfai J, Vincze T, Guiliano D, Blaxter M, Eisen J, Slatko B.

Int J Parasitol. 2002 Feb;32(2):159-66.

PMID:
11812492
8.

The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: a candidate target for anti-filarial therapies.

Foster JM, Raverdy S, Ganatra MB, Colussi PA, Taron CH, Carlow CK.

Parasitol Res. 2009 Apr;104(5):1047-52. doi: 10.1007/s00436-008-1287-7. Epub 2008 Nov 29.

PMID:
19043737
9.

Molecular characterization of an rsmD-like rRNA methyltransferase from the Wolbachia endosymbiont of Brugia malayi and antifilarial activity of specific inhibitors of the enzyme.

Rana AK, Chandra S, Siddiqi MI, Misra-Bhattacharya S.

Antimicrob Agents Chemother. 2013 Aug;57(8):3843-56. doi: 10.1128/AAC.02264-12. Epub 2013 Jun 3.

10.

Preliminary analysis to target pyruvate phosphate dikinase from wolbachia endosymbiont of Brugia malayi for designing anti-filarial agents.

Palayam M, Lakshminarayanan K, Radhakrishnan M, Krishnaswamy G.

Interdiscip Sci. 2012 Mar;4(1):74-82. doi: 10.1007/s12539-011-0109-2. Epub 2012 Mar 6.

PMID:
22392278
11.

Prior killing of intracellular bacteria Wolbachia reduces inflammatory reactions and improves antifilarial efficacy of diethylcarbamazine in rodent model of Brugia malayi.

Shakya S, Bajpai P, Sharma S, Misra-Bhattacharya S.

Parasitol Res. 2008 Apr;102(5):963-72. doi: 10.1007/s00436-007-0861-8. Epub 2008 Jan 8.

PMID:
18180957
12.

Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi.

Holman AG, Davis PJ, Foster JM, Carlow CK, Kumar S.

BMC Microbiol. 2009 Nov 28;9:243. doi: 10.1186/1471-2180-9-243.

13.

The Wolbachia endosymbiont of Brugia malayi has an active pyruvate phosphate dikinase.

Raverdy S, Foster JM, Roopenian E, Carlow CK.

Mol Biochem Parasitol. 2008 Aug;160(2):163-6. doi: 10.1016/j.molbiopara.2008.04.014. Epub 2008 May 4.

PMID:
18539347
14.

Glucose and Glycogen Metabolism in Brugia malayi Is Associated with Wolbachia Symbiont Fitness.

Voronin D, Bachu S, Shlossman M, Unnasch TR, Ghedin E, Lustigman S.

PLoS One. 2016 Apr 14;11(4):e0153812. doi: 10.1371/journal.pone.0153812. eCollection 2016.

15.

Tetracycline treatment targeting Wolbachia affects expression of an array of proteins in Brugia malayi parasite.

Dangi A, Vedi S, Nag JK, Paithankar S, Singh MP, Kar SK, Dube A, Misra-Bhattacharya S.

Proteomics. 2009 Sep;9(17):4192-208. doi: 10.1002/pmic.200800324.

PMID:
19722191
16.
17.

Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria.

Keffer JL, Huecas S, Hammill JT, Wipf P, Andreu JM, Bewley CA.

Bioorg Med Chem. 2013 Sep 15;21(18):5673-8. doi: 10.1016/j.bmc.2013.07.033. Epub 2013 Jul 25.

18.

Molecular characterization of NAD+-dependent DNA ligase from Wolbachia endosymbiont of lymphatic filarial parasite Brugia malayi.

Shrivastava N, Nag JK, Misra-Bhattacharya S.

PLoS One. 2012;7(7):e41113. doi: 10.1371/journal.pone.0041113. Epub 2012 Jul 16.

19.

Wolbachia translation initiation factor-1 is copiously expressed by the adult, microfilariae and infective larvae of Brugia malayi and competitively inhibited by tetracycline.

Nag JK, Shrivastava N, Tiwari M, Gupta Cl, Bajpai P, Chahar D, Misra-Bhattacharya S.

Acta Trop. 2014 Oct;138:51-9. doi: 10.1016/j.actatropica.2014.04.033. Epub 2014 Jun 11.

PMID:
24929215
20.

Population dynamics of Wolbachia bacterial endosymbionts in Brugia malayi.

McGarry HF, Egerton GL, Taylor MJ.

Mol Biochem Parasitol. 2004 May;135(1):57-67.

PMID:
15287587

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