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Items: 1 to 20 of 103

1.

Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study.

Leng S, Stidley CA, Liu Y, Edlund CK, Willink RP, Han Y, Landi MT, Thun M, Picchi MA, Bruse SE, Crowell RE, Van Den Berg D, Caporaso NE, Amos CI, Siegfried JM, Tesfaigzi Y, Gilliland FD, Belinsky SA.

Cancer Res. 2012 Feb 1;72(3):707-15. doi: 10.1158/0008-5472.CAN-11-3194. Epub 2011 Dec 2.

2.

15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers.

Leng S, Liu Y, Weissfeld JL, Thomas CL, Han Y, Picchi MA, Edlund CK, Willink RP, Gaither Davis AL, Do KC, Nukui T, Zhang X, Burki EA, Van Den Berg D, Romkes M, Gauderman WJ, Crowell RE, Tesfaigzi Y, Stidley CA, Amos CI, Siegfried JM, Gilliland FD, Belinsky SA.

J Natl Cancer Inst. 2015 Feb 23;107(5). pii: djv035. doi: 10.1093/jnci/djv035.

3.

Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers.

Belinsky SA, Palmisano WA, Gilliland FD, Crooks LA, Divine KK, Winters SA, Grimes MJ, Harms HJ, Tellez CS, Smith TM, Moots PP, Lechner JF, Stidley CA, Crowell RE.

Cancer Res. 2002 Apr 15;62(8):2370-7.

4.

Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers.

Wu YH, Tsai Chang JH, Cheng YW, Wu TC, Chen CY, Lee H.

Oncogene. 2007 Jul 19;26(33):4761-73. Epub 2007 Feb 26.

PMID:
17325666
5.

Similar DNA methylation pattern in lung tumours from smokers and never-smokers with second-hand tobacco smoke exposure.

Scesnaite A, Jarmalaite S, Mutanen P, Anttila S, Nyberg F, Benhamou S, Boffetta P, Husgafvel-Pursiainen K.

Mutagenesis. 2012 Jul;27(4):423-9. doi: 10.1093/mutage/ger092. Epub 2012 Jan 4.

PMID:
22217548
6.

Differential DNA hypermethylation of critical genes mediates the stage-specific tobacco smoke-induced neoplastic progression of lung cancer.

Russo AL, Thiagalingam A, Pan H, Califano J, Cheng KH, Ponte JF, Chinnappan D, Nemani P, Sidransky D, Thiagalingam S.

Clin Cancer Res. 2005 Apr 1;11(7):2466-70.

7.

Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.

Scherf DB, Sarkisyan N, Jacobsson H, Claus R, Bermejo JL, Peil B, Gu L, Muley T, Meister M, Dienemann H, Plass C, Risch A.

Oncogene. 2013 Jul 11;32(28):3329-38. doi: 10.1038/onc.2012.344. Epub 2012 Sep 3.

8.

Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.

Leng S, Wu G, Collins LB, Thomas CL, Tellez CS, Jauregui AR, Picchi MA, Zhang X, Juri DE, Desai D, Amin SG, Crowell RE, Stidley CA, Liu Y, Swenberg JA, Lin Y, Wathelet MG, Gilliland FD, Belinsky SA.

Cancer Res. 2015 Aug 1;75(15):3108-17. doi: 10.1158/0008-5472.CAN-15-0243. Epub 2015 Jul 16.

9.

Altered regulation of DNA ligase IV activity by aberrant promoter DNA methylation and gene amplification in colorectal cancer.

Kuhmann C, Li C, Kloor M, Salou M, Weigel C, Schmidt CR, Ng LW, Tsui WW, Leung SY, Yuen ST, Becker N, Weichenhan D, Plass C, Schmezer P, Chan TL, Popanda O.

Hum Mol Genet. 2014 Apr 15;23(8):2043-54. doi: 10.1093/hmg/ddt599. Epub 2013 Nov 26.

PMID:
24282031
10.
11.

Aberrant p16 promoter methylation in smokers and former smokers with nonsmall cell lung cancer.

Jarmalaite S, Kannio A, Anttila S, Lazutka JR, Husgafvel-Pursiainen K.

Int J Cancer. 2003 Oct 10;106(6):913-8.

12.

A case-control study of the association of the polymorphisms and haplotypes of DNA ligase I with lung and upper-aerodigestive-tract cancers.

Lee YC, Morgenstern H, Greenland S, Tashkin DP, Papp J, Sinsheimer J, Cao W, Hashibe M, You NC, Mao JT, Cozen W, Mack TM, Zhang ZF.

Int J Cancer. 2008 Apr 1;122(7):1630-8.

13.

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.

Wang X, Chorley BN, Pittman GS, Kleeberger SR, Brothers J 2nd, Liu G, Spira A, Bell DA.

PLoS One. 2010 Aug 3;5(8):e11934. doi: 10.1371/journal.pone.0011934.

14.

The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.

Leng S, Bernauer AM, Hong C, Do KC, Yingling CM, Flores KG, Tessema M, Tellez CS, Willink RP, Burki EA, Picchi MA, Stidley CA, Prados MD, Costello JF, Gilliland FD, Crowell RE, Belinsky SA.

Clin Cancer Res. 2011 Apr 1;17(7):2014-23. doi: 10.1158/1078-0432.CCR-10-3026. Epub 2011 Feb 25.

15.

Promoter hypermethylation of multiple genes in early gastric adenocarcinoma and precancerous lesions.

Zou XP, Zhang B, Zhang XQ, Chen M, Cao J, Liu WJ.

Hum Pathol. 2009 Nov;40(11):1534-42. doi: 10.1016/j.humpath.2009.01.029. Epub 2009 Aug 19.

PMID:
19695681
16.

Promoter hypermethylation profile of kidney cancer with new proapoptotic p53 target genes and clinical implications.

Christoph F, Weikert S, Kempkensteffen C, Krause H, Schostak M, K├Âllermann J, Miller K, Schrader M.

Clin Cancer Res. 2006 Sep 1;12(17):5040-6.

17.

Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers.

Liu Y, Gao W, Siegfried JM, Weissfeld JL, Luketich JD, Keohavong P.

BMC Cancer. 2007 May 3;7:74.

18.

Gene promoter methylation in plasma and sputum increases with lung cancer risk.

Belinsky SA, Klinge DM, Dekker JD, Smith MW, Bocklage TJ, Gilliland FD, Crowell RE, Karp DD, Stidley CA, Picchi MA.

Clin Cancer Res. 2005 Sep 15;11(18):6505-11.

19.

Detection of RASSF1A aberrant promoter hypermethylation in sputum from chronic smokers and ductal carcinoma in situ from breast cancer patients.

Honorio S, Agathanggelou A, Schuermann M, Pankow W, Viacava P, Maher ER, Latif F.

Oncogene. 2003 Jan 9;22(1):147-50.

PMID:
12527916
20.

PTEN, RASSF1 and DAPK site-specific hypermethylation and outcome in surgically treated stage I and II nonsmall cell lung cancer patients.

Buckingham L, Penfield Faber L, Kim A, Liptay M, Barger C, Basu S, Fidler M, Walters K, Bonomi P, Coon J.

Int J Cancer. 2010 Apr 1;126(7):1630-9. doi: 10.1002/ijc.24896.

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