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Items: 1 to 20 of 99

1.

The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2.

Gan Z, Burkart-Hartman EM, Han DH, Finck B, Leone TC, Smith EY, Ayala JE, Holloszy J, Kelly DP.

Genes Dev. 2011 Dec 15;25(24):2619-30. doi: 10.1101/gad.178434.111. Epub 2011 Dec 1.

2.

Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.

Burkart EM, Sambandam N, Han X, Gross RW, Courtois M, Gierasch CM, Shoghi K, Welch MJ, Kelly DP.

J Clin Invest. 2007 Dec;117(12):3930-9.

3.

The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet.

Pérez-Schindler J, Svensson K, Vargas-Fernández E, Santos G, Wahli W, Handschin C.

Diabetologia. 2014 Nov;57(11):2405-12. doi: 10.1007/s00125-014-3352-3. Epub 2014 Aug 13.

4.

Transcriptional profiling reveals divergent roles of PPARalpha and PPARbeta/delta in regulation of gene expression in mouse liver.

Sanderson LM, Boekschoten MV, Desvergne B, Müller M, Kersten S.

Physiol Genomics. 2010 Mar 3;41(1):42-52. doi: 10.1152/physiolgenomics.00127.2009. Epub 2009 Dec 15. Erratum in: Physiol Genomics. 2010 Jul 7;42(2):317.

5.

Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle.

Liang X, Liu L, Fu T, Zhou Q, Zhou D, Xiao L, Liu J, Kong Y, Xie H, Yi F, Lai L, Vega RB, Kelly DP, Smith SR, Gan Z.

J Biol Chem. 2016 Dec 2;291(49):25306-25318. Epub 2016 Oct 13.

PMID:
27738103
6.

PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.

Salvadó L, Barroso E, Gómez-Foix AM, Palomer X, Michalik L, Wahli W, Vázquez-Carrera M.

Diabetologia. 2014 Oct;57(10):2126-35. doi: 10.1007/s00125-014-3331-8. Epub 2014 Jul 26.

PMID:
25063273
7.
8.

trans-Cinnamaldehyde stimulates mitochondrial biogenesis through PGC-1α and PPARβ/δ leading to enhanced GLUT4 expression.

Gannon NP, Schnuck JK, Mermier CM, Conn CA, Vaughan RA.

Biochimie. 2015 Dec;119:45-51. doi: 10.1016/j.biochi.2015.10.001. Epub 2015 Oct 9.

PMID:
26449747
9.

Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise.

Kannisto K, Chibalin A, Glinghammar B, Zierath JR, Hamsten A, Ehrenborg E.

Int J Mol Med. 2006 Jan;17(1):45-52.

PMID:
16328010
10.

Leucine stimulates PPARβ/δ-dependent mitochondrial biogenesis and oxidative metabolism with enhanced GLUT4 content and glucose uptake in myotubes.

Schnuck JK, Sunderland KL, Gannon NP, Kuennen MR, Vaughan RA.

Biochimie. 2016 Sep-Oct;128-129:1-7. doi: 10.1016/j.biochi.2016.06.009. Epub 2016 Jun 23.

PMID:
27345255
11.

Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.

Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, Way JM, Winegar DA, Corton JC, Dohm GL, Kraus WE.

J Biol Chem. 2002 Jul 19;277(29):26089-97. Epub 2002 May 6.

12.

Calcineurin regulates skeletal muscle metabolism via coordinated changes in gene expression.

Long YC, Glund S, Garcia-Roves PM, Zierath JR.

J Biol Chem. 2007 Jan 19;282(3):1607-14. Epub 2006 Nov 15.

13.

Peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism.

Gilde AJ, van der Lee KA, Willemsen PH, Chinetti G, van der Leij FR, van der Vusse GJ, Staels B, van Bilsen M.

Circ Res. 2003 Mar 21;92(5):518-24. Epub 2003 Feb 6.

14.

Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism.

Gan Z, Rumsey J, Hazen BC, Lai L, Leone TC, Vega RB, Xie H, Conley KE, Auwerx J, Smith SR, Olson EN, Kralli A, Kelly DP.

J Clin Invest. 2013 Jun;123(6):2564-75. doi: 10.1172/JCI67652. Epub 2013 May 8.

15.

α-Lipoic acid up-regulates expression of peroxisome proliferator-activated receptor β in skeletal muscle: involvement of the JNK signaling pathway.

Rousseau AS, Sibille B, Murdaca J, Mothe-Satney I, Grimaldi PA, Neels JG.

FASEB J. 2016 Mar;30(3):1287-99. doi: 10.1096/fj.15-280453. Epub 2015 Dec 9.

16.

Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy.

Planavila A, Laguna JC, Vázquez-Carrera M.

J Biol Chem. 2005 Apr 29;280(17):17464-71. Epub 2005 Feb 22.

17.

Double gene deletion reveals the lack of cooperation between PPARalpha and PPARbeta in skeletal muscle.

Bedu E, Desplanches D, Pequignot J, Bordier B, Desvergne B.

Biochem Biophys Res Commun. 2007 Jun 15;357(4):877-81. Epub 2007 Apr 9.

PMID:
17466944
18.

Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells.

Abbot EL, McCormack JG, Reynet C, Hassall DG, Buchan KW, Yeaman SJ.

FEBS J. 2005 Jun;272(12):3004-14.

19.

Peroxisome proliferator-activated receptor β/δ induces myogenesis by modulating myostatin activity.

Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R.

J Biol Chem. 2012 Apr 13;287(16):12935-51. doi: 10.1074/jbc.M111.319145. Epub 2012 Feb 23. Retraction in: J Biol Chem. 2016 Jul 1;291(27):14391.

20.

A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.

Finck BN, Bernal-Mizrachi C, Han DH, Coleman T, Sambandam N, LaRiviere LL, Holloszy JO, Semenkovich CF, Kelly DP.

Cell Metab. 2005 Feb;1(2):133-44.

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