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Items: 1 to 20 of 105

1.

Negative cross-talk between calcium-sensing receptor and β-catenin signaling systems in colonic epithelium.

Rey O, Chang W, Bikle D, Rozengurt N, Young SH, Rozengurt E.

J Biol Chem. 2012 Jan 6;287(2):1158-67. doi: 10.1074/jbc.M111.274589. Epub 2011 Nov 17.

2.

Regulation of E-cadherin and beta-catenin by Ca2+ in colon carcinoma is dependent on calcium-sensing receptor expression and function.

Bhagavathula N, Hanosh AW, Nerusu KC, Appelman H, Chakrabarty S, Varani J.

Int J Cancer. 2007 Oct 1;121(7):1455-62.

4.

Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552.

Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E.

Am J Physiol Cell Physiol. 2016 Apr 1;310(7):C542-57. doi: 10.1152/ajpcell.00302.2015. Epub 2016 Jan 6.

5.

The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon.

Aggarwal A, Prinz-Wohlgenannt M, Gröschel C, Tennakoon S, Meshcheryakova A, Chang W, Brown EM, Mechtcheriakova D, Kállay E.

Mol Cancer. 2015 Mar 18;14:61. doi: 10.1186/s12943-015-0330-4.

6.

Calcium, calcium-sensing receptor and growth control in the colonic mucosa.

Varani J.

Histol Histopathol. 2011 Jun;26(6):769-79. doi: 10.14670/HH-26.769. Review.

7.

Calcium, calcium-sensing receptor and colon cancer.

Whitfield JF.

Cancer Lett. 2009 Mar 8;275(1):9-16. doi: 10.1016/j.canlet.2008.07.001. Epub 2008 Aug 23. Review.

PMID:
18725175
8.

Calcium sensing receptor suppresses human pancreatic tumorigenesis through a novel NCX1/Ca(2+)/β-catenin signaling pathway.

Tang B, Chow JY, Dong TX, Yang SM, Lu DS, Carethers JM, Dong H.

Cancer Lett. 2016 Jul 10;377(1):44-54. doi: 10.1016/j.canlet.2016.04.027. Epub 2016 Apr 20.

PMID:
27108064
9.

Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells.

MacLeod RJ, Hayes M, Pacheco I.

Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G403-11. Epub 2007 Apr 26.

PMID:
17463182
10.

Active vitamin D potentiates the anti-neoplastic effects of calcium in the colon: A cross talk through the calcium-sensing receptor.

Aggarwal A, Höbaus J, Tennakoon S, Prinz-Wohlgenannt M, Graça J, Price SA, Heffeter P, Berger W, Baumgartner-Parzer S, Kállay E.

J Steroid Biochem Mol Biol. 2016 Jan;155(Pt B):231-8. doi: 10.1016/j.jsbmb.2015.02.006. Epub 2015 Mar 7.

11.

CaSR function in the intestine: Hormone secretion, electrolyte absorption and secretion, paracrine non-canonical Wnt signaling and colonic crypt cell proliferation.

Macleod RJ.

Best Pract Res Clin Endocrinol Metab. 2013 Jun;27(3):385-402. doi: 10.1016/j.beem.2013.05.005. Epub 2013 Jun 21. Review.

PMID:
23856267
12.

The calcium-sensing receptor: A promising target for prevention of colorectal cancer.

Aggarwal A, Prinz-Wohlgenannt M, Tennakoon S, Höbaus J, Boudot C, Mentaverri R, Brown EM, Baumgartner-Parzer S, Kállay E.

Biochim Biophys Acta. 2015 Sep;1853(9):2158-67. doi: 10.1016/j.bbamcr.2015.02.011. Epub 2015 Feb 18.

13.

Peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses colonic epithelial cell turnover and colon carcinogenesis through inhibition of the beta-catenin/T cell factor (TCF) pathway.

Fujisawa T, Nakajima A, Fujisawa N, Takahashi H, Ikeda I, Tomimoto A, Yonemitsu K, Nakajima N, Kudo C, Wada K, Kubota N, Terauchi Y, Kadowaki T, Nakagama H, Blumberg RS.

J Pharmacol Sci. 2008 Apr;106(4):627-38. Epub 2008 Apr 5.

14.

γ-Glutamyl cysteine and γ-glutamyl valine inhibit TNF-α signaling in intestinal epithelial cells and reduce inflammation in a mouse model of colitis via allosteric activation of the calcium-sensing receptor.

Zhang H, Kovacs-Nolan J, Kodera T, Eto Y, Mine Y.

Biochim Biophys Acta. 2015 May;1852(5):792-804. doi: 10.1016/j.bbadis.2014.12.023. Epub 2015 Jan 3.

15.

Dual alterations in casein kinase I-epsilon and GSK-3beta modulate beta-catenin stability in hyperproliferating colonic epithelia.

Umar S, Wang Y, Morris AP, Sellin JH.

Am J Physiol Gastrointest Liver Physiol. 2007 Feb;292(2):G599-607. Epub 2006 Oct 19.

PMID:
17053159
16.

Functional expression of the extracellular calcium sensing receptor (CaSR) in equine umbilical cord matrix size-sieved stem cells.

Martino NA, Lange-Consiglio A, Cremonesi F, Valentini L, Caira M, Guaricci AC, Ambruosi B, Sciorsci RL, Lacalandra GM, Reshkin SJ, Dell'Aquila ME.

PLoS One. 2011 Mar 17;6(3):e17714. doi: 10.1371/journal.pone.0017714.

17.

Molecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretion.

Xie R, Dong X, Wong C, Vallon V, Tang B, Sun J, Yang S, Dong H.

J Biol Chem. 2014 Dec 12;289(50):34642-53. doi: 10.1074/jbc.M114.592774. Epub 2014 Oct 20.

18.

Calcium-sensing receptor stimulates Cl(-)- and SCFA-dependent but inhibits cAMP-dependent HCO3(-) secretion in colon.

Tang L, Peng M, Liu L, Chang W, Binder HJ, Cheng SX.

Am J Physiol Gastrointest Liver Physiol. 2015 May 15;308(10):G874-83. doi: 10.1152/ajpgi.00341.2014. Epub 2015 Mar 19.

19.

Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane.

Jouret F, Wu J, Hull M, Rajendran V, Mayr B, Schöfl C, Geibel J, Caplan MJ.

J Cell Sci. 2013 Nov 15;126(Pt 22):5132-42. doi: 10.1242/jcs.127555. Epub 2013 Sep 6.

20.

Extracellular calcium sensing receptor stimulation in human colonic epithelial cells induces intracellular calcium oscillations and proliferation inhibition.

Rey O, Young SH, Jacamo R, Moyer MP, Rozengurt E.

J Cell Physiol. 2010 Oct;225(1):73-83. doi: 10.1002/jcp.22198.

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