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Items: 1 to 20 of 101

1.

Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter.

Barnard TJ, Gumbart J, Peterson JH, Noinaj N, Easley NC, Dautin N, Kuszak AJ, Tajkhorshid E, Bernstein HD, Buchanan SK.

J Mol Biol. 2012 Jan 6;415(1):128-42. doi: 10.1016/j.jmb.2011.10.049. Epub 2011 Nov 7.

2.

Crystal structure of the passenger domain of the Escherichia coli autotransporter EspP.

Khan S, Mian HS, Sandercock LE, Chirgadze NY, Pai EF.

J Mol Biol. 2011 Nov 11;413(5):985-1000. doi: 10.1016/j.jmb.2011.09.028. Epub 2011 Sep 22.

3.

Autotransporter structure reveals intra-barrel cleavage followed by conformational changes.

Barnard TJ, Dautin N, Lukacik P, Bernstein HD, Buchanan SK.

Nat Struct Mol Biol. 2007 Dec;14(12):1214-20. Epub 2007 Nov 11.

4.
5.

Cleavage of a bacterial autotransporter by an evolutionarily convergent autocatalytic mechanism.

Dautin N, Barnard TJ, Anderson DE, Bernstein HD.

EMBO J. 2007 Apr 4;26(7):1942-52. Epub 2007 Mar 8.

6.

Stepwise folding of an autotransporter passenger domain is not essential for its secretion.

Kang'ethe W, Bernstein HD.

J Biol Chem. 2013 Dec 6;288(49):35028-38. doi: 10.1074/jbc.M113.515635. Epub 2013 Oct 28.

7.
8.

Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis.

Brown NG, Shanker S, Prasad BV, Palzkill T.

J Biol Chem. 2009 Nov 27;284(48):33703-12. doi: 10.1074/jbc.M109.053819. Epub 2009 Oct 6.

9.

Structure and function relationship of the autotransport and proteolytic activity of EspP from Shiga toxin-producing Escherichia coli.

Brockmeyer J, Spelten S, Kuczius T, Bielaszewska M, Karch H.

PLoS One. 2009 Jul 1;4(7):e6100. doi: 10.1371/journal.pone.0006100.

10.

Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.

Zarivach R, Deng W, Vuckovic M, Felise HB, Nguyen HV, Miller SI, Finlay BB, Strynadka NC.

Nature. 2008 May 1;453(7191):124-7. doi: 10.1038/nature06832.

PMID:
18451864
11.

Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing.

Ding Y, Xu MQ, Ghosh I, Chen X, Ferrandon S, Lesage G, Rao Z.

J Biol Chem. 2003 Oct 3;278(40):39133-42. Epub 2003 Jul 23.

12.

Sequential and spatially restricted interactions of assembly factors with an autotransporter beta domain.

Ieva R, Tian P, Peterson JH, Bernstein HD.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):E383-91. doi: 10.1073/pnas.1103827108. Epub 2011 Jun 6.

13.

Efficient secretion of a folded protein domain by a monomeric bacterial autotransporter.

Skillman KM, Barnard TJ, Peterson JH, Ghirlando R, Bernstein HD.

Mol Microbiol. 2005 Nov;58(4):945-58.

14.

Hydroxide and proton migration in aquaporins.

Jensen MØ, Röthlisberger U, Rovira C.

Biophys J. 2005 Sep;89(3):1744-59. Epub 2005 Jun 10.

15.

The thiolase reaction mechanism: the importance of Asn316 and His348 for stabilizing the enolate intermediate of the Claisen condensation.

Meriläinen G, Poikela V, Kursula P, Wierenga RK.

Biochemistry. 2009 Nov 24;48(46):11011-25. doi: 10.1021/bi901069h.

PMID:
19842716
16.

Molecular basis for the structural stability of an enclosed β-barrel loop.

Tian P, Bernstein HD.

J Mol Biol. 2010 Sep 17;402(2):475-89. doi: 10.1016/j.jmb.2010.07.035. Epub 2010 Jul 23.

17.

X-ray crystal structure of the passenger domain of plasmid encoded toxin(Pet), an autotransporter enterotoxin from enteroaggregative Escherichia coli (EAEC).

Domingo Meza-Aguilar J, Fromme P, Torres-Larios A, Mendoza-Hernández G, Hernandez-Chiñas U, Arreguin-Espinosa de Los Monteros RA, Eslava Campos CA, Fromme R.

Biochem Biophys Res Commun. 2014 Mar 7;445(2):439-44. doi: 10.1016/j.bbrc.2014.02.016. Epub 2014 Feb 12.

18.

The active site of a lon protease from Methanococcus jannaschii distinctly differs from the canonical catalytic Dyad of Lon proteases.

Im YJ, Na Y, Kang GB, Rho SH, Kim MK, Lee JH, Chung CH, Eom SH.

J Biol Chem. 2004 Dec 17;279(51):53451-7. Epub 2004 Sep 28.

19.

A QM/QM investigation of the hUNG2 reaction surface: the untold tale of a catalytic residue.

Przybylski JL, Wetmore SD.

Biochemistry. 2011 May 17;50(19):4218-27. doi: 10.1021/bi2003394. Epub 2011 Apr 20.

PMID:
21473605
20.

Incorporation of a polypeptide segment into the beta-domain pore during the assembly of a bacterial autotransporter.

Ieva R, Skillman KM, Bernstein HD.

Mol Microbiol. 2008 Jan;67(1):188-201. Epub 2007 Nov 27.

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