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A subset of methylated CpG sites differentiate psoriatic from normal skin.

Roberson ED, Liu Y, Ryan C, Joyce CE, Duan S, Cao L, Martin A, Liao W, Menter A, Bowcock AM.

J Invest Dermatol. 2012 Mar;132(3 Pt 1):583-92. doi: 10.1038/jid.2011.348. Epub 2011 Nov 10.


Whole-genome DNA methylation in skin lesions from patients with psoriasis vulgaris.

Zhang P, Zhao M, Liang G, Yin G, Huang D, Su F, Zhai H, Wang L, Su Y, Lu Q.

J Autoimmun. 2013 Mar;41:17-24. doi: 10.1016/j.jaut.2013.01.001. Epub 2013 Jan 29.


A role for epigenetics in psoriasis: methylated Cytosine-Guanine sites differentiate lesional from nonlesional skin and from normal skin.

Gudjonsson JE, Krueger G.

J Invest Dermatol. 2012 Mar;132(3 Pt 1):506-8. doi: 10.1038/jid.2011.364.


Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α.

Langkilde A, Olsen LC, Sætrom P, Drabløs F, Besenbacher S, Raaby L, Johansen C, Iversen L.

PLoS One. 2016 Dec 22;11(12):e0167437. doi: 10.1371/journal.pone.0167437. eCollection 2016.


Epigenome-Wide Association Analysis Identified Nine Skin DNA Methylation Loci for Psoriasis.

Zhou F, Wang W, Shen C, Li H, Zuo X, Zheng X, Yue M, Zhang C, Yu L, Chen M, Zhu C, Yin X, Tang M, Li Y, Chen G, Wang Z, Liu S, Zhou Y, Zhang F, Zhang W, Li C, Yang S, Sun L, Zhang X.

J Invest Dermatol. 2016 Apr;136(4):779-87. doi: 10.1016/j.jid.2015.12.029. Epub 2015 Dec 29.


Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis.

Zhou F, Shen C, Xu J, Gao J, Zheng X, Ko R, Dou J, Cheng Y, Zhu C, Xu S, Tang X, Zuo X, Yin X, Cui Y, Sun L, Tsoi LC, Hsu YH, Yang S, Zhang X.

Clin Epigenetics. 2016 Dec 5;8:131. doi: 10.1186/s13148-016-0297-z. eCollection 2016.


Effect of Adalimumab on Gene Expression Profiles of Psoriatic Skin and Blood.

Chow M, Lai K, Ahn R, Gupta R, Arron S, Liao W.

J Drugs Dermatol. 2016 Aug 1;15(8):988-94.


Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin.

Gudjonsson JE, Ding J, Li X, Nair RP, Tejasvi T, Qin ZS, Ghosh D, Aphale A, Gumucio DL, Voorhees JJ, Abecasis GR, Elder JT.

J Invest Dermatol. 2009 Dec;129(12):2795-804. doi: 10.1038/jid.2009.173. Epub 2009 Jul 2.


Reproducible Novel Transcriptional Differences Between Psoriatic Lesional and Non-Lesional Skin Show Increased Inflammation and Metabolism.

Aires DJ, Rockwell G, Menter A, Nielson C, Wick J, Sedivy S, Tawfik O, Bowcock A, Sinha AA.

J Drugs Dermatol. 2015 Aug;14(8):794-800.


Adalimumab for severe psoriasis and psoriatic arthritis: an open-label study in 30 patients previously treated with other biologics.

Papoutsaki M, Chimenti MS, Costanzo A, Talamonti M, Zangrilli A, Giunta A, Bianchi L, Chimenti S.

J Am Acad Dermatol. 2007 Aug;57(2):269-75. Epub 2007 Jun 18.


Genomic imprinting in psoriasis and atopic dermatitis: A review.

Nguyen CM, Liao W.

J Dermatol Sci. 2015 Nov;80(2):89-93. doi: 10.1016/j.jdermsci.2015.08.004. Epub 2015 Aug 24. Review.


Hypermethylation of HLA-C may be an epigenetic marker in psoriasis.

Chen M, Wang Y, Yao X, Li C, Jiang M, Cui P, Wang B.

J Dermatol Sci. 2016 Jul;83(1):10-6. doi: 10.1016/j.jdermsci.2016.04.003. Epub 2016 Apr 14.


Expression of genes involved in the regulation of p16 in psoriatic involved skin.

Mark EB, Jonsson M, Asp J, Wennberg AM, Mölne L, Lindahl A.

Arch Dermatol Res. 2006 Apr;297(10):459-67. Epub 2006 Mar 22.


Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN.

Keermann M, Kõks S, Reimann E, Prans E, Abram K, Kingo K.

BMC Genomics. 2015 Apr 19;16:322. doi: 10.1186/s12864-015-1508-2.


Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies.

Bowcock AM, Shannon W, Du F, Duncan J, Cao K, Aftergut K, Catier J, Fernandez-Vina MA, Menter A.

Hum Mol Genet. 2001 Aug 15;10(17):1793-805.


Gene expression profiling of Japanese psoriatic skin reveals an increased activity in molecular stress and immune response signals.

Kulski JK, Kenworthy W, Bellgard M, Taplin R, Okamoto K, Oka A, Mabuchi T, Ozawa A, Tamiya G, Inoko H.

J Mol Med (Berl). 2005 Dec;83(12):964-75. Epub 2005 Nov 11.


Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models.

Gudjonsson JE, Ding J, Johnston A, Tejasvi T, Guzman AM, Nair RP, Voorhees JJ, Abecasis GR, Elder JT.

J Invest Dermatol. 2010 Jul;130(7):1829-40. doi: 10.1038/jid.2010.36. Epub 2010 Mar 11.


DNA methylation and gene expression changes in monozygotic twins discordant for psoriasis: identification of epigenetically dysregulated genes.

Gervin K, Vigeland MD, Mattingsdal M, Hammerø M, Nygård H, Olsen AO, Brandt I, Harris JR, Undlien DE, Lyle R.

PLoS Genet. 2012 Jan;8(1):e1002454. doi: 10.1371/journal.pgen.1002454. Epub 2012 Jan 19.


[The methylation locus and frequency pattern on p16 INK4a gene promoter CpG in epidermis of patients with psoriasis].

Chen M, Cui PG, Yao X, Cao YH, Gong JQ, Li AS, Chen ZQ.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Dec;24(6):674-6. Chinese.


MiRNA expression in psoriatic skin: reciprocal regulation of hsa-miR-99a and IGF-1R.

Lerman G, Avivi C, Mardoukh C, Barzilai A, Tessone A, Gradus B, Pavlotsky F, Barshack I, Polak-Charcon S, Orenstein A, Hornstein E, Sidi Y, Avni D.

PLoS One. 2011;6(6):e20916. doi: 10.1371/journal.pone.0020916. Epub 2011 Jun 7.

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