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Items: 1 to 20 of 113


Cutting edge: A role for inside-out signaling in TCR regulation of CD28 ligand binding.

Sanchez-Lockhart M, Kim M, Miller J.

J Immunol. 2011 Dec 1;187(11):5515-9. doi: 10.4049/jimmunol.1102497. Epub 2011 Nov 7.


T cell receptor signaling can directly enhance the avidity of CD28 ligand binding.

Sanchez-Lockhart M, Rojas AV, Fettis MM, Bauserman R, Higa TR, Miao H, Waugh RE, Miller J.

PLoS One. 2014 Feb 24;9(2):e89263. doi: 10.1371/journal.pone.0089263. eCollection 2014.


Signals and sequences that control CD28 localization to the central region of the immunological synapse.

Sanchez-Lockhart M, Graf B, Miller J.

J Immunol. 2008 Dec 1;181(11):7639-48.


Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.

Yokosuka T, Saito T.

Immunol Rev. 2009 May;229(1):27-40. doi: 10.1111/j.1600-065X.2009.00779.x. Review.


Two pathways of costimulation through CD28.

Miller J, Baker C, Cook K, Graf B, Sanchez-Lockhart M, Sharp K, Wang X, Yang B, Yoshida T.

Immunol Res. 2009 Dec;45(2-3):159-72. doi: 10.1007/s12026-009-8097-6. Epub 2009 Feb 13. Review.


TCRs genetically linked to CD28 and CD3ε do not mispair with endogenous TCR chains and mediate enhanced T cell persistence and anti-melanoma activity.

Govers C, Sebestyén Z, Roszik J, van Brakel M, Berrevoets C, Szöőr Á, Panoutsopoulou K, Broertjes M, Van T, Vereb G, Szöllősi J, Debets R.

J Immunol. 2014 Nov 15;193(10):5315-26. doi: 10.4049/jimmunol.1302074. Epub 2014 Oct 15.


CD28 sensitizes TCR Ca²⁺ signaling during Ag-independent polarization of plasma membrane rafts.

Byrum JN, Van Komen JS, Rodgers W.

J Immunol. 2013 Sep 15;191(6):3073-81. doi: 10.4049/jimmunol.1300485. Epub 2013 Aug 21.


Recruitment of Sprouty1 to immune synapse regulates T cell receptor signaling.

Lee JS, Lee JE, Oh YM, Park JB, Choi H, Choi CY, Kim IH, Lee SH, Choi K.

J Immunol. 2009 Dec 1;183(11):7178-86. doi: 10.4049/jimmunol.0803799. Epub 2009 Nov 13.


Negative regulation of TCR signaling by linker for activation of X cells via phosphotyrosine-dependent and -independent mechanisms.

Shapiro MJ, Nguyen CT, Aghajanian H, Zhang W, Shapiro VS.

J Immunol. 2008 Nov 15;181(10):7055-61.


Regulation of NF-κB induction by TCR/CD28.

Cheng J, Montecalvo A, Kane LP.

Immunol Res. 2011 Aug;50(2-3):113-7. doi: 10.1007/s12026-011-8216-z. Review.


Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists.

Lühder F, Huang Y, Dennehy KM, Guntermann C, Müller I, Winkler E, Kerkau T, Ikemizu S, Davis SJ, Hanke T, Hünig T.

J Exp Med. 2003 Apr 21;197(8):955-66.


Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation.

Tao X, Constant S, Jorritsma P, Bottomly K.

J Immunol. 1997 Dec 15;159(12):5956-63.


Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis.

Le Bras S, Foucault I, Foussat A, Brignone C, Acuto O, Deckert M.

J Biol Chem. 2004 Apr 9;279(15):15550-60. Epub 2004 Jan 16.


CD28 signal enhances apoptosis of CD8 T cells after strong TCR ligation.

Yu XZ, Martin PJ, Anasetti C.

J Immunol. 2003 Mar 15;170(6):3002-6.


A CD28-associated signaling pathway leading to cytokine gene transcription and T cell proliferation without TCR engagement.

Siefken R, Klein-Hessling S, Serfling E, Kurrle R, Schwinzer R.

J Immunol. 1998 Aug 15;161(4):1645-51.


Cutting edge: monovalency of CD28 maintains the antigen dependence of T cell costimulatory responses.

Dennehy KM, Elias F, Zeder-Lutz G, Ding X, Altschuh D, Lühder F, Hünig T.

J Immunol. 2006 May 15;176(10):5725-9.

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