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Items: 1 to 20 of 114

1.

RNF34 is a cold-regulated E3 ubiquitin ligase for PGC-1α and modulates brown fat cell metabolism.

Wei P, Pan D, Mao C, Wang YX.

Mol Cell Biol. 2012 Jan;32(2):266-75. doi: 10.1128/MCB.05674-11.

2.

Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.

Trausch-Azar JS, Abed M, Orian A, Schwartz AL.

J Cell Physiol. 2015 Apr;230(4):842-52. doi: 10.1002/jcp.24812.

3.

Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.

Hondares E, Rosell M, Díaz-Delfín J, Olmos Y, Monsalve M, Iglesias R, Villarroya F, Giralt M.

J Biol Chem. 2011 Dec 16;286(50):43112-22. doi: 10.1074/jbc.M111.252775.

4.

Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis.

Park JH, Kang HJ, Lee YK, Kang H, Kim J, Chung JH, Chang JS, McPherron AC, Lee SB.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6074-9. doi: 10.1073/pnas.1504391112.

5.

Transcriptional control of brown fat determination by PRDM16.

Seale P, Kajimura S, Yang W, Chin S, Rohas LM, Uldry M, Tavernier G, Langin D, Spiegelman BM.

Cell Metab. 2007 Jul;6(1):38-54.

6.

NT-PGC-1α protein is sufficient to link β3-adrenergic receptor activation to transcriptional and physiological components of adaptive thermogenesis.

Chang JS, Fernand V, Zhang Y, Shin J, Jun HJ, Joshi Y, Gettys TW.

J Biol Chem. 2012 Mar 16;287(12):9100-11. doi: 10.1074/jbc.M111.320200.

7.

SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis.

Olson BL, Hock MB, Ekholm-Reed S, Wohlschlegel JA, Dev KK, Kralli A, Reed SI.

Genes Dev. 2008 Jan 15;22(2):252-64. doi: 10.1101/gad.1624208.

8.

Intramolecular control of protein stability, subnuclear compartmentalization, and coactivator function of peroxisome proliferator-activated receptor gamma coactivator 1alpha.

Sano M, Tokudome S, Shimizu N, Yoshikawa N, Ogawa C, Shirakawa K, Endo J, Katayama T, Yuasa S, Ieda M, Makino S, Hattori F, Tanaka H, Fukuda K.

J Biol Chem. 2007 Aug 31;282(35):25970-80.

9.

Dietary fat interacts with QTLs controlling induction of Pgc-1 alpha and Ucp1 during conversion of white to brown fat.

Coulter AA, Bearden CM, Liu X, Koza RA, Kozak LP.

Physiol Genomics. 2003 Jul 7;14(2):139-47.

PMID:
12746468
10.

Ring finger protein 34 (RNF34) interacts with and promotes γ-aminobutyric acid type-A receptor degradation via ubiquitination of the γ2 subunit.

Jin H, Chiou TT, Serwanski DR, Miralles CP, Pinal N, De Blas AL.

J Biol Chem. 2014 Oct 17;289(42):29420-36. doi: 10.1074/jbc.M114.603068.

11.

The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes.

Wang L, Liu J, Saha P, Huang J, Chan L, Spiegelman B, Moore DD.

Cell Metab. 2005 Oct;2(4):227-38.

12.

Combinatorial transcription factor regulation of the cyclic AMP-response element on the Pgc-1alpha promoter in white 3T3-L1 and brown HIB-1B preadipocytes.

Karamitri A, Shore AM, Docherty K, Speakman JR, Lomax MA.

J Biol Chem. 2009 Jul 31;284(31):20738-52. doi: 10.1074/jbc.M109.021766.

13.

Twist-1 is a PPARdelta-inducible, negative-feedback regulator of PGC-1alpha in brown fat metabolism.

Pan D, Fujimoto M, Lopes A, Wang YX.

Cell. 2009 Apr 3;137(1):73-86. doi: 10.1016/j.cell.2009.01.051.

14.

The E3 ligase RNF34 is a novel negative regulator of the NOD1 pathway.

Zhang R, Zhao J, Song Y, Wang X, Wang L, Xu J, Song C, Liu F.

Cell Physiol Biochem. 2014;33(6):1954-62.

15.

Defective thermoregulation, impaired lipid metabolism, but preserved adrenergic induction of gene expression in brown fat of mice lacking C/EBPbeta.

Carmona MC, Hondares E, Rodríguez de la Concepción ML, Rodríguez-Sureda V, Peinado-Onsurbe J, Poli V, Iglesias R, Villarroya F, Giralt M.

Biochem J. 2005 Jul 1;389(Pt 1):47-56.

16.

The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.

Tron AE, Arai T, Duda DM, Kuwabara H, Olszewski JL, Fujiwara Y, Bahamon BN, Signoretti S, Schulman BA, DeCaprio JA.

Mol Cell. 2012 Apr 13;46(1):67-78. doi: 10.1016/j.molcel.2012.02.005.

17.

ERRγ enhances UCP1 expression and fatty acid oxidation in brown adipocytes.

Dixen K, Basse AL, Murholm M, Isidor MS, Hansen LH, Petersen MC, Madsen L, Petrovic N, Nedergaard J, Quistorff B, Hansen JB.

Obesity (Silver Spring). 2013 Mar;21(3):516-24. doi: 10.1002/oby.20067.

18.

FBXL5 modulates HIF-1α transcriptional activity by degradation of CITED2.

Machado-Oliveira G, Guerreiro E, Matias AC, Facucho-Oliveira J, Pacheco-Leyva I, Bragança J.

Arch Biochem Biophys. 2015 Jun 15;576:61-72. doi: 10.1016/j.abb.2015.04.012.

PMID:
25956243
19.

Regulation of Brown and White Adipocyte Transcriptome by the Transcriptional Coactivator NT-PGC-1α.

Kim J, Fernand VE, Henagan TM, Shin J, Huypens P, Newman S, Gettys TW, Chang JS.

PLoS One. 2016 Jul 25;11(7):e0159990. doi: 10.1371/journal.pone.0159990.

20.

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